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  <xsd:element id="abus_CumulativeContributionforProduct" name="CumulativeContributionforProduct" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
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  <xsd:element abstract="true" id="abus_DocumentAndEntityInformationAbstract" name="DocumentAndEntityInformationAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
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  <xsd:element id="abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" name="EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_EnantigenMember" name="EnantigenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward" name="FairValueLiabilitiesMeasuredonRecurringBasisRollForward" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_FairValueOfWarrantsExercisedInThePeriod" name="FairValueOfWarrantsExercisedInThePeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_InProcessResearchandDevelopmentAntigenInhibitorsMember" name="InProcessResearchandDevelopmentAntigenInhibitorsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_InProcessResearchandDevelopmentImmuneModulatorsMember" name="InProcessResearchandDevelopmentImmuneModulatorsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_InProcessResearchandDevelopmentcccDNASterilizersMember" name="InProcessResearchandDevelopmentcccDNASterilizersMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability" name="IncreaseDecreaseInFairValueOfContingentConsiderationLiability" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
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  <xsd:element id="abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions" name="IncreaseDecreaseinFairValueofLiabilityClassifiedOptions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense" name="LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense" name="LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="abus_LicenseUpfrontPayment" name="LicenseUpfrontPayment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="abus_LicensingFeesMilestoneAndRoyaltyPaymentsAbstract" name="LicensingFeesMilestoneAndRoyaltyPaymentsAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_LoanPayableAbstract" name="LoanPayableAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_MarqiboCommercialSalesMember" name="MarqiboCommercialSalesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_MarqiboMember" name="MarqiboMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_MaximumContributionForProduct" name="MaximumContributionForProduct" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="abus_MilestonePayment" name="MilestonePayment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="abus_MonsantoMember" name="MonsantoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_NumberOfChemotherapyProductsWithWorldwideLicenses" name="NumberOfChemotherapyProductsWithWorldwideLicenses" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="abus_Numberofseriesofcompounds" name="Numberofseriesofcompounds" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="abus_OptionExercisedContractualOptionRevenueAmount" name="OptionExercisedContractualOptionRevenueAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="abus_OptionalExercisedContractualOptionAmount" name="OptionalExercisedContractualOptionAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="abus_OtherMilestoneandRoyaltyPaymentsMember" name="OtherMilestoneandRoyaltyPaymentsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_PADCo.Member" name="PADCo.Member" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_PercentOfCostsFundedByTPC" name="PercentOfCostsFundedByTPC" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_PotentialContractFundingAmount" name="PotentialContractFundingAmount" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_ProgramsInPreClinicalDevelopment" name="ProgramsInPreClinicalDevelopment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="abus_PromissoryNoteMember" name="PromissoryNoteMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments" name="ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments" name="ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment" name="ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_ResearchFundingPeriod" name="ResearchFundingPeriod" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_ResearchFundingPeriodRenewableOption" name="ResearchFundingPeriodRenewableOption" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_RestrictedInvestmentTerm" name="RestrictedInvestmentTerm" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_RoyaltiesPaidOrAccrued" name="RoyaltiesPaidOrAccrued" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="abus_RoyaltyGuaranteesCommitmentsPercentage" name="RoyaltyGuaranteesCommitmentsPercentage" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_RoyaltyPayable" name="RoyaltyPayable" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="abus_TalonTherapeuticsMember" name="TalonTherapeuticsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_WarrantsExercised" name="WarrantsExercised" nillable="true" substitutionGroup="xbrli:item" type="xbrli:sharesItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_WeightedAverageNumberOfCommonSharesAbstract" name="WeightedAverageNumberOfCommonSharesAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="abus_WellsFargoMember" name="WellsFargoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements" name="WhollyOwnedSubsidiariesIncludedinFinancialStatements" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
</xsd:schema>





