Significant accounting policies
Significant Accounting Policies [Text Block]
Share-Based Compensation Expense Allocation, Income Statement Location [Axis]
Share-Based Compensation Expense Allocation, Income Statement Location [Axis]
Share-Based Compensation Expense Allocation, Income Statement Location
Statistical Measurement [Domain]
Statistical Measurement [Domain]
Investments in marketable securities
Investment, Policy [Policy Text Block]
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Weighted average number of common shares
Weighted Average Number Of Common Shares [Abstract]
Weighted average number of common shares
Settled Litigation
Settled Litigation [Member]
Total deferred tax assets
Deferred Tax Assets (Liabilities), Gross
Deferred Tax Assets (Liabilities), Gross
Award Timing Predetermined
Award Timing Predetermined [Flag]
Related Party Transaction [Axis]
Related Party Transaction [Axis]
Entity File Number
Entity File Number
Additional paid-in capital
Additional Paid-in Capital [Member]
Liability Related To Future Royalties [Roll Forward]
Liability Related To Future Royalties [Roll Forward]
Liability Related To Future Royalties
Impairment of property and equipment
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Tabular List, Table
Tabular List [Table Text Block]
Leases [Abstract]
Leases [Abstract]
Permanent and other differences
Effective Income Tax Rate Reconciliation, Permanent And Other Reconciling Items, Amount
Effective Income Tax Rate Reconciliation, Permanent And Other Reconciling Items, Amount
Recent accounting pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
License Agreement Milestone payment maximum
License Agreement Milestone payment maximum
License Agreement Milestone payment maximum
Interest income
Interest Income, Interest-Earning Asset
Deferred license revenue, non-current
Deferred Revenue, Noncurrent
OMERS
OMERS [Member]
OMERS
Type of Restructuring [Domain]
Type of Restructuring [Domain]
Tax credits: research and development credits
Federal R&D credit
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
License
License [Member]
Gross Unrealized Loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Basic (in USD per share)
Basic net loss attributable to common shareholders per share (in USD per share)
Earnings Per Share, Basic
Adjustment to Compensation:
Adjustment to Compensation [Axis]
Related party transactions
Related Party Transactions Disclosure [Text Block]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Accounts payable and accrued liabilities
Increase (Decrease) in Accounts Payable and Accrued Liabilities
Bona fide collaboration Percentage [Member]
Bona fide collaboration Percentage
Bona fide collaboration Percentage
Liabilities
Liabilities, Fair Value Disclosure [Abstract]
Number of shares remaining for issuance
Common Stock, Capital Shares Reserved for Future Issuance
Royalty guarantees commitments percentage
Royalty Guarantees Commitments Percentage
Represents the royalty guarantees commitments percentage.
US treasury bills
US Treasury Bill Securities [Member]
Schedule of revenue recognized under collaborations, contracts and licensing agreements
Collaborative Arrangement and Arrangement Other than Collaborative [Table Text Block]
Stock, Class of Stock [Table]
Stock, Class of Stock [Table]
Discount rate
Measurement Input, Discount Rate [Member]
Schedule of Segment Reporting Information, by Segment
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Issuance of common shares upon settlement of RSUs (in shares)
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Issuance of common shares pursuant to exercise of ESPP options (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Revenue, remaining performance obligation, amount
Revenue, Remaining Performance Obligation, Amount
Measurement Input Type [Domain]
Measurement Input Type [Domain]
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Principles of consolidation
Consolidation, Policy [Policy Text Block]
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Deductible stock options
Deferred Tax Assets, Tax Deferred Expense, Compensation And Benefits, Stock Options
Deferred Tax Assets, Tax Deferred Expense, Compensation And Benefits, Stock Options
Options outstanding and expected to vest
Stock options
Share-Based Payment Arrangement, Option [Member]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Cash and cash equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Income taxes paid
Income Taxes Paid
Grantee Status [Domain]
Grantee Status [Domain]
Litigation settlement amount awarded
Litigation Settlement, Amount Awarded from Other Party
Percent
Effective Income Tax Rate Reconciliation, Percent [Abstract]
U.S. research and experimental expenditures capitalization
Deferred Tax Assets, Tax Deferred Expense
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Total stockholders' equity
Beginning balance
Ending balance
Equity, Attributable to Parent
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Debt Securities, Available-for-sale [Table]
Debt Securities, Available-for-Sale [Table]
Insider Trading Policies and Procedures [Line Items]
Stock-based compensation expense
Share-Based Payment Arrangement, Expense
Schedule of property and equipment
Property, Plant and Equipment [Table Text Block]
Tax Period [Domain]
Tax Period [Domain]
Current assets:
Assets, Current [Abstract]
Arbutus Plans
Arbutus Plans [Member]
Arbutus Plans [Member]
Total liabilities and stockholders' equity
Liabilities and Equity
Foreign currency translation and functional currency conversion
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Fair Value, Measurements, Recurring
Fair Value, Recurring [Member]
Number of optioned common shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Concentrations of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Liabilities and stockholders' equity
Liabilities and Equity [Abstract]
Domestic tax effects:
State and Local Jurisdiction [Member]
Cover [Abstract]
Cash and cash equivalents
Cash Equivalents, Fair Value
Cash and Cash Equivalents, Fair Value Disclosure
Other
Deferred Tax Assets, Other
Maximum
Maximum [Member]
Equity Method Investment [Table]
Equity Method Investment [Table]
General Business Tax Credit Carryforward
General Business Tax Credit Carryforward [Member]
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Schedule of lease maturity
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Registration Statement [Axis]
Registration Statement [Axis]
Registration Statement
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Pay vs Performance Disclosure [Line Items]
Present value of lease payments
Operating Lease, Liability
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Qilu
Qilu [Member]
Qilu
Entity Shell Company
Entity Shell Company
Proceeds from sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment
Change in deferred license revenue
Increase (Decrease) in Deferred Revenue
Stockholders’ equity
Statement of Stockholders' Equity [Abstract]
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Company Selected Measure Amount
Company Selected Measure Amount
2028
Lessee, Operating Lease, Liability, to be Paid, Year Three
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Measurement Input Type [Axis]
Measurement Input Type [Axis]
Name
Measure Name
Restructuring Reserve
Restructuring Reserve
Schedule of income before income tax, domestic and foreign
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Domestic
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Schedule of allocation of stock-based compensation
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Lease liability, current
Operating Lease, Liability, Current
Class of Stock [Line Items]
Class of Stock [Line Items]
Document Fiscal Period Focus
Document Fiscal Period Focus
Award Timing Method
Award Timing Method [Text Block]
Litigation Case [Domain]
Litigation Case [Domain]
Furniture and fixtures
Furniture and Fixtures [Member]
Award Type [Axis]
Award Type [Axis]
Outstanding debt
Long-Term Debt
Legal Entity [Axis]
Legal Entity [Axis]
Total assets
Assets
Research and development costs
Research, Development, and Computer Software, Policy [Policy Text Block]
Investment, Name [Domain]
Investment, Name [Domain]
Stock-based compensation
Share-Based Payment Arrangement [Policy Text Block]
Non-cash royalty revenue
Non-Cash Royalty [Member]
Non-Cash Royalty
Trading Symbol
Trading Symbol
2029
Lessee, Operating Lease, Liability, to be Paid, Year Four
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Research and development employee expense, lab supplies and overhead
Research and development employee expense, lab supplies and overhead
Research and development employee expense, lab supplies and overhead
Laboratory equipment
Lab equipment
Laboratory Equipment [Member]
Represents the laboratory equipment.
Deferred income taxes
Income Tax, Policy [Policy Text Block]
Entity Address, City or Town
Entity Address, City or Town
OPERATING ACTIVITIES
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Tax credits: research and development credits
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Adjustments and reconciling items
Segment Reporting, Other Segment Item, Amount
Effect of foreign exchange rate changes on cash and cash equivalents
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Restricted Stock Units (RSUs)
Restricted Stock Units (RSUs) [Member]
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Assets
Assets, Fair Value Disclosure [Abstract]
Restructuring expense
Restructuring Costs
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Debt Securities, Available-for-sale [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Number of options outstanding (in shares)
Balance - Number of optioned common shares (in shares)
Balance - Number of optioned common shares (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Restructuring And Workforce Reduction
Restructuring And Workforce Reduction [Member]
Restructuring And Workforce Reduction
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Level 2
Fair Value, Inputs, Level 2 [Member]
Document Financial Statement Error Correction [Flag]
Document Financial Statement Error Correction [Flag]
Provincial tax
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
Equity method investments
Equity Method Investments
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
US government bonds
US Government Bonds [Member]
US Government Bonds [Member]
Business Combination [Domain]
Business Combination [Domain]
Common shares, shares outstanding (in shares)
Common Stock, Shares, Outstanding
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table]
Share-Based Payment Arrangement, Option, Exercise Price Range [Table]
Aggregate share sales price
Common Stock, Value, Subscriptions
Effective annual interest rate of royalty liability
Effective Annual Interest Rate Of Royalty Liability
Effective Annual Interest Rate Of Royalty Liability
Investments in marketable securities
Marketable Securities [Table Text Block]
Plan Name [Axis]
Plan Name [Axis]
Property and equipment
Property, Plant and Equipment, Policy [Policy Text Block]
PEO
PEO [Member]
Lease Contractual Term [Domain]
Lease Contractual Term [Domain]
Discount rate on shares
Common Stock, Discount On Shares, Percentage
Common Stock, Discount On Shares, Percentage
Severance and continuing benefits
Employee Severance [Member]
Disposition of investments in marketable securities
Proceeds from Sale, Maturity and Collection of Investments
Interest income
Investment Income, Interest
Net change in operating items:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Issuance of common shares pursuant to exercise of stock options
Stock Issued During Period, Value, Stock Options Exercised
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Products and Services [Table]
Nature of Operation, Product Information, Concentration of Risk [Table]
Expected volatility (historical)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Deficit
Retained Earnings [Member]
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Income Tax Jurisdiction [Axis]
Income Tax Jurisdiction [Axis]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Restatement Determination Date
Restatement Determination Date
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Share-Based Payment Arrangement [Abstract]
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Income Statement [Abstract]
Income Statement [Abstract]
Income tax expense
Income Tax Expense (Benefit)
Sale of Stock [Domain]
Sale of Stock [Domain]
Investments in marketable securities, current
Investments, Fair Value Disclosure
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Product and Service [Domain]
Product and Service [Domain]
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost, Current
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Schedule of changes in fair value of contingent consideration
Business Combination, Contingent Consideration [Table Text Block]
Cost
Property, Plant and Equipment, Gross
Cash, cash equivalents and short-term investments
Cash, Cash Equivalents, and Short-Term Investments
Restructuring
Share-Based Compensation Expense Allocation, Restructuring Charges [Member]
Share-Based Compensation Expense Allocation, Restructuring Charges
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Total
Liabilities, Fair Value Disclosure
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Issuance of common shares pursuant to exercise of stock options
Proceeds from Stock Options Exercised
City Area Code
City Area Code
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Cash payment for collaborations
Proceeds from Collaborators
All Trading Arrangements
All Trading Arrangements [Member]
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Royalty interest sold, maximum royalties for buyer
Royalty Interest Sold, Maximum Royalties For Buyer
Royalty Interest Sold, Maximum Royalties For Buyer
Investment tax credits available to reduce Canadian federal income taxes
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
INVESTING ACTIVITIES
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
General and administrative
General and Administrative Expense
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Investments in marketable securities, non-current
Long-Term Investments
Related Party Transactions [Abstract]
Related Party Transactions [Abstract]
Audit Information [Abstract]
Audit Information
Effective Income Tax Rate Reconciliation [Table]
Effective Income Tax Rate Reconciliation [Table]
Equity Method Investments and Joint Ventures [Abstract]
Equity Method Investments and Joint Ventures [Abstract]
Number of wholly-owned subsidiaries
Number Of Wholly-Owned Subsidiaries
Number Of Wholly-Owned Subsidiaries
Payroll accruals
Accrued Payroll Current
Accrued Payroll Current
Debt Securities, Realized Gain (Loss)
Debt Securities, Realized Gain (Loss)
Useful lives (in years)
Property, Plant and Equipment, Useful Life
Percent of litigation settlement to be received after costs
Percent Of Litigation Settlement To Be Received, After Costs
Percent Of Litigation Settlement To Be Received, After Costs
Subsequent event
Subsequent Event [Member]
Schedule of weighted average Black-Scholes option-pricing assumptions and resultant fair values
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Effective Income Tax Rate Reconciliation [Line Items]
Effective Income Tax Rate Reconciliation [Line Items]
Schedule of Equity Method Investments [Line Items]
Schedule of Equity Method Investments [Line Items]
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
Schedule of lease cost
Lease, Cost [Table Text Block]
PEO Total Compensation Amount
PEO Total Compensation Amount
Depreciation and amortization
Depreciation
Depreciation
Money market funds
Money Market Funds [Member]
Collaborations and licenses
Collaboration And Contracts [Member]
Collaboration And Contracts [Member]
Accrued interest payable
Deferred Tax Asset, Interest Carryforward
Lease Contractual Term [Axis]
Lease Contractual Term [Axis]
Other milestone and royalty payments
Other Milestones and Royalty Payments [Member]
Other Milestones and Royalty Payments
Royalties from sales of ONPATTRO
Onpattro - Cash Royalty [Member]
Onpattro - Cash Royalty
Research and Development, Contract to Perform for Others [Table]
Research and Development, Contract to Perform for Others [Table]
Equity Components [Axis]
Equity Components [Axis]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Auditor Name
Auditor Name
Organization
Nature of Operations [Text Block]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Number of reportable segments
Number of Reportable Segments
Contingent consideration, liability, measurement input
Business Combination, Contingent Consideration, Liability, Measurement Input
Fixed lease payment
Fixed Lease, Cost
Fixed Lease, Cost
Restructuring Cost and Reserve [Line Items]
Restructuring Cost and Reserve [Line Items]
Other Performance Measure, Amount
Other Performance Measure, Amount
Weighted average exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Entity Address, State or Province
Entity Address, State or Province
Related Party [Domain]
Related and Nonrelated Parties [Domain]
Total current liabilities
Liabilities, Current
Amount
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract]
Litigation Status [Axis]
Litigation Status [Axis]
Individual:
Individual [Axis]
Income Tax Jurisdiction [Domain]
Income Tax Jurisdiction [Domain]
Contingencies and Commitments [Line Items]
Contingencies and Commitments [Line Items]
Document Annual Report
Document Annual Report
Entity [Domain]
Entity [Domain]
Accrual of lease-related operating expenses
Other Restructuring [Member]
Net cash provided by investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Transaction costs related to sale of future royalties
Transaction Costs Related To Sale Of Future Royalties
Transaction Costs Related To Sale Of Future Royalties
Document Fiscal Year Focus
Document Fiscal Year Focus
Basis of presentation
Basis of Accounting, Policy [Policy Text Block]
Right of use asset
Operating Lease, Right-of-Use Asset
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Ownership interest (percent)
Subsidiary, Ownership Percentage, Noncontrolling Owner
Canadian research and development deductions
Deferred Tax Asset, In-Process Research and Development
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Entity Interactive Data Current
Entity Interactive Data Current
Non-cash impairment of lease right-of-use asset
Use Rights [Member]
Operating Lease, Cost
Operating Lease, Cost
Plan Name [Domain]
Plan Name [Domain]
Unearned compensation expense, recognition period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Issuance of common shares pursuant to exercise of options (in shares)
Options exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Equity [Abstract]
Equity [Abstract]
Sale of future royalties
Liabilities Related To Sale Of Future Royalties [Text Block]
Liabilities Related To Sale Of Future Royalties
Revenue from collaborations and licenses
Revenue from Contract with Customer [Policy Text Block]
Non-taxable and non-deductible items: stock options
Stock-based compensation
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Segment Reporting Disclosure
Segment Reporting Disclosure [Text Block]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Property, Plant and Equipment, Type [Axis]
Long-Lived Tangible Asset [Axis]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Ownership [Domain]
Ownership [Domain]
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Leases
Lessee, Leases [Policy Text Block]
Common shares reserved for issuance
Employee Stock Ownership Plan (ESOP), Shares in ESOP
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Other non-current assets
Other Assets, Noncurrent
Entity Central Index Key
Entity Central Index Key
PEO Name
PEO Name
Revenue
Total revenue
Revenues
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Foreign tax rate differential
Difference due to income taxed at foreign rates
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount
Contingent consideration
Fair value of contingent consideration (in $000s)
Contingent consideration
Liability at beginning of the period
Liability at end of the period
Business Combination, Contingent Consideration, Liability, Noncurrent
Arrangement Duration
Trading Arrangement Duration
Schedule of Segment Reporting Information, by Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Computer and office equipment
Computer hardware and software
Computer Equipment [Member]
Segments [Axis]
Segments [Axis]
Prepaid expenses and other assets
Increase (Decrease) in Prepaid Expense and Other Assets
Exercise Price
Award Exercise Price
Entity Filer Category
Entity Filer Category
Class of Stock [Domain]
Class of Stock [Domain]
Local Phone Number
Local Phone Number
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Canadian federal and provincial income tax rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Issuance of common shares pursuant to the Open Market Sale Agreement
Proceeds from Issuance of Common Stock, Open Market Sale agreement
Proceeds from Issuance of Common Stock, Open Market Sale agreement
Shares price (in USD per share)
Share Price
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Stock-based compensation
Share-Based Payment Arrangement [Text Block]
Equity method investment
Deferred Tax Assets, Equity Method Investments
Imdusiran IM-PROVE I, II & III clinical trials expense
Imdusiran IM-PROVE I, II & III clinical trials expense
Imdusiran IM-PROVE I, II & III clinical trials expense
Assets
Assets [Abstract]
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Schedule of estimated useful lives of property and equipment
Property, Plant and Equipment, Estimated Useful Lives [Table Text Block]
Tabular disclosure of property, plant and equipment, estimated useful lives.
Restricted stock units forfeited, canceled or expired (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Fair value measurements
Fair Value Disclosures [Text Block]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Entity Address, Address Line One
Entity Address, Address Line One
Deferred revenue
Deferred Revenue
Research and development
Research and Development Expense
Restricted stock units forfeited, canceled or expired (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures and Expirations
Accumulated other comprehensive loss
AOCI Attributable to Parent [Member]
Investment, Name [Axis]
Investment, Name [Axis]
Lease liability, non-current
Operating Lease, Liability, Noncurrent
Entity Voluntary Filers
Entity Voluntary Filers
AB-101-001 Phase 1a/1b clinical trial expense
AB-101-001 Phase 1a/b clinical trial expense
AB-101-001 Phase 1a/b clinical trial expense
Premium percentage on closing stock price
Premium on Closing Stock Price
Premium on Closing Stock Price
Royalty interest, Percent interest
Royalty interest, Percent interest
Royalty interest, % interest
Equity method investment, percentage or revenue entitled
Equity Method Investment, Percentage Of Revenue Entitled
Equity Method Investment, Percentage Of Revenue Entitled
Ownership [Axis]
Ownership [Axis]
Royalty, percentage of interest sold
Royalty, Percentage of Interest Sold
Royalty, Percentage of Interest Sold
Restructuring, Settlement and Impairment Provisions
Restructuring, Settlement and Impairment Provisions
2016 and 2011 Plans
2016 And 2011 Plans [Member]
2016 And 2011 Plans
Fair Value as of Grant Date
Award Grant Date Fair Value
Property, Plant and Equipment [Abstract]
Property, Plant and Equipment [Abstract]
Entity Registrant Name
Entity Registrant Name
Dec 2024 Registration Statements
Dec 2024 Registration Stmts [Member]
Dec 2024 Registration Stmts
Discount rate
Lessee, Operating Lease, Discount Rate
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
ONPATTRO, global net sales
ONPATTRO, global net sales [Member]
ONPATTRO, global net sales
Net operating losses
Operating Loss Carryforwards
Investment tax credit carryforward
Investment Tax Credit Carryforward [Member]
Purchase of investments in marketable securities
Payments to Acquire Investments
Dec 2024 Prospectus Supplement
Dec 2024 Prospectus Supplement [Member]
Dec 2024 Prospectus Supplement
Title and Position [Domain]
Title and Position [Domain]
Unearned compensation expense
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Domestic provincial tax effects:
State and Local Tax Jurisdiction, Other [Member]
Total
Assets, Fair Value Disclosure
Number of loss positions
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Restricted stock units granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted
Counterparty Name [Domain]
Counterparty Name [Domain]
2027
Lessee, Operating Lease, Liability, to be Paid, Year Two
Net accretion of investments in marketable securities
Accretion (Amortization) of Discounts and Premiums, Investments
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Components of Deferred Tax Assets [Line Items]
Tax Credit Carryforward [Line Items]
Weighted-average term remaining
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Accrued Investment Income Receivable
Accrued Investment Income Receivable
Schedule of accounts payable and accrued liabilities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Related Party [Axis]
Related and Nonrelated Parties [Axis]
Weighted average grant date fair value (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Title
Trading Arrangement, Individual Title
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Royalty interest sold, percentage of sales, annual revenue threshold of highest tier
Royalty Interest Sold, Percentage Of Sales, Annual Revenue Threshold Of Highest Tier
Royalty Interest Sold, Percentage Of Sales, Annual Revenue Threshold Of Highest Tier
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Restatement Determination Date:
Restatement Determination Date [Axis]
Research and development accruals
Accrued Research and Development, Current
Accrued Research and Development, Current
Non-PEO NEO
Non-PEO NEO [Member]
Intrinsic value of stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Restructuring and Related Costs
Restructuring and Related Costs [Table Text Block]
Issuance of common shares pursuant to exercise of ESPP
Stock Issued During Period, Value, Employee Stock Purchase Plan
Deferred tax assets, operating loss carryforwards, subject to expiration
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Royalty payable
Royalty Payable
Represents the royalty payable.
Other Liabilities Disclosure [Line Items]
Other Liabilities Disclosure [Line Items]
Other Liabilities Disclosure [Line Items]
Sale of Stock [Axis]
Sale of Stock [Axis]
Gross Unrealized Gain
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Name
Trading Arrangement, Individual Name
Equity Award [Domain]
Award Type [Domain]
One-Time Upfront Cash Payment
One-Time Upfront Cash Payment [Member]
One-Time Upfront Cash Payment
2026
Lessee, Operating Lease, Liability, to be Paid, Year One
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Leasehold improvements
Leasehold Improvements [Member]
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Compensation Amount
Outstanding Recovery Compensation Amount
Expected dividends
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Foreign tax rate differential
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Balance at beginning of period (in dollars per share)
Balance at end of period (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Restructuring Type [Axis]
Restructuring Type [Axis]
Change in fair value of contingent consideration
Increase in fair value of contingent consideration
Increase in fair value of liability
Business Combination, Contingent Consideration, Change in Contingent Consideration, Liability, Increase (Decrease)
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Revenue
Revenues [Abstract]
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Consulting Services
Consulting Services [Member]
Consulting Services
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Vested stock options
Vested [Member]
Vested [Member]
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Non-cash royalty revenue
Liability From Sale Of Future Royalties, Non Cash Royalty Income
Liability From Sale Of Future Royalties, Non Cash Royalty Income
Tax value in excess of accounting value in lease inducements
Tax value in excess of accounting value in lease inducements
Represents the deferred tax asset tax value in excess of accounting value in lease inducements.
Financial Instruments [Domain]
Financial Instruments [Domain]
Unrealized gain (loss) on available-for-sale securities
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Litigation Case [Axis]
Litigation Case [Axis]
Genevant
Genevant
Genevant Sciences Corporation [Member]
Genevant Sciences Corporation [Member]
United States
Foreign Tax Jurisdiction [Member]
Auditor Firm ID
Auditor Firm ID
Investment tax credits available to reduce provincial income taxes
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
Segments [Domain]
Segments [Domain]
Additional damages sought, pending appeals process
Loss Contingency, Damages Sought, Value
Foreign
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Performance shares
Performance Shares [Member]
Investments in marketable securities
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Other deferred costs, gross
Other Deferred Costs, Gross
Non-cash interest expense
Liability From Sale Of Future Royalties, Non Cash Expense
Liability From Sale Of Future Royalties, Non Cash Expense
Minimum
Minimum [Member]
Income Tax Authority, Name [Domain]
Income Tax Authority, Name [Domain]
Other
Effective Income Tax Rate Reconciliation, Tax Credit, Other, Percent
Issuance of common shares pursuant to the Open Market Sale Agreement
Stock Issued During Period, Value, New Issues, Open Market Sale Agreement
Stock Issued During Period, Value, New Issues, Open Market Sale Agreement
Non-cash stock compensation modification expense
Special Termination Benefits [Member]
Amortization of other deferred charges
Amortization of Other Deferred Charges
Accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Net loss attributable to common shareholders per share
Earnings Per Share, Policy [Policy Text Block]
Company Selected Measure Name
Company Selected Measure Name
Probability of success
Probability of Sucess [Member]
Probability of Sucess
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Cash paid for amounts included in the measurement of lease liabilities
Operating Lease, Payments
Issuance of common shares pursuant to ESPP
Proceeds from Stock Plans
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
All Executive Categories
All Executive Categories [Member]
Schedule of components of deferred tax assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Issued and outstanding: 192,531,225 and 189,963,492 as of December 31, 2025 and 2024, respectively.
Common Stock, Value, Issued
Tax Period [Axis]
Tax Period [Axis]
Premiums earned, net
Premiums Earned, Net
Restructuring Plan [Domain]
Restructuring Plan [Domain]
Investments in marketable securities, current
Short-Term Investments
Employee
Share-Based Payment Arrangement, Employee [Member]
Contingencies and commitments
Commitments and Contingencies Disclosure [Text Block]
Revenue recognized for tax purposes in excess of revenue recognized for accounting purposes
Revenue recognized for tax purposes in excess of revenue recognized for accounting purposes
Represents the deferred tax asset revenue recognized for tax purpose in excess of revenue recognized for accounting purposes.
Title and Position [Axis]
Title and Position [Axis]
Diluted (in shares)
Weighted average number of common shares - diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Weighted Average Grant Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested Options Forfeited, Weighted Average Grant Date Fair Value
Business Combination [Axis]
Business Combination [Axis]
Entity Small Business
Entity Small Business
Income Tax Disclosure [Abstract]
Income Tax Disclosure [Abstract]
Costs related to collaboration
Other Cost and Expense, Operating
Document Transition Report
Document Transition Report
Investment in Genevant
Equity Method Investments [Policy Text Block]
US corporate bonds
US Corporate Bonds [Member]
US Corporate Bonds
Ownership interest in equity method investment (as a percent)
Equity Method Investment, Ownership Percentage
Underlying Securities
Award Underlying Securities Amount
Net deferred tax assets (liabilities)
Deferred Tax Assets, Net
Equity Component [Domain]
Equity Component [Domain]
Document Period End Date
Document Period End Date
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Maximum royalty payment
License Agreement Maximum Development And Regulatory Milestone Payments Per Royalty
License Agreement Maximum Development And Regulatory Royalty Payment per Royalty
Options forfeited, canceled or expired (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period
Income taxes
Income Tax Disclosure [Text Block]
Accounts payable and accrued liabilities
Supplemental Balance Sheet Disclosures [Text Block]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Revenue from Contract with Customer [Abstract]
Revenue from Contract with Customer [Abstract]
Non-cash royalty revenue
Non-cash royalty revenue
Non Cash Royalty Revenue Related To Sale Of Future Royalties
Non Cash Royalty Revenue Related To Sale Of Future Royalties
Annual Revenue Threshold
Annual Revenue Threshold
Annual Revenue Threshold
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Line Items]
Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items]
Document Type
Document Type
Restricted stock units (in shares)
Balance at beginning of period (in shares)
Balance at end of period (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Level 3
Fair Value, Inputs, Level 3 [Member]
Name
Outstanding Recovery, Individual Name
Additional paid-in capital
Additional Paid in Capital
Product and Service [Axis]
Product and Service [Axis]
Proceeds from issuance of common stock
Proceeds from issuance of common stock
Proceeds from Issuance of Common Stock
Variable lease payment
Variable Lease, Cost
Activity related to net liability
Liabilities Related To Sale Of Future Royalties Roll Forward [Table Text Block]
Liabilities Related To Sale Of Future Royalties Roll Forward
Litigation Status [Domain]
Litigation Status [Domain]
All Individuals
All Individuals [Member]
Contract close-out costs
Contract Termination [Member]
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Share-Based Compensation Expense Allocation, Income Statement Location [Domain]
Share-Based Compensation Expense Allocation, Income Statement Location [Domain]
Share-Based Compensation Expense Allocation, Income Statement Location [Domain]
Acquisition of property and equipment
Payments to Acquire Property, Plant, and Equipment
Name
Forgone Recovery, Individual Name
Total current assets
Assets, Current
Statistical Measurement [Axis]
Statistical Measurement [Axis]
Non-cash interest expense
Non Cash Interest Expense Related To Sale Of Future Royalties
Non Cash Interest Expense Related To Sale Of Future Royalties
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Segment Reporting Information, Profit (Loss) [Abstract]
Segment net loss
Segment net loss
Other Liabilities Disclosure [Abstract]
Other Liabilities Disclosure [Abstract]
Severance And Employee Benefit Costs and Lease Expenses
Severance And Employee Benefit Costs and Lease Expenses [Member]
Severance And Employee Benefit Costs and Lease Expenses
Options forfeited, canceled or expired - Weighted average exercise price (in CAD and USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Intrinsic value of options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Common Stock, Shares Authorized, Unlimited [Fixed List]
Common Stock, Shares Authorized, Unlimited [Fixed List]
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Unrealized gain on available-for-sale securities
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Current liabilities:
Liabilities, Current [Abstract]
Research and development credits
Deferred Tax Assets, Tax Credit Carryforwards, Research
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Fair Value, Liabilities Measured on Recurring Basis [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis [Roll Forward]
Total operating expenses
Operating Expenses
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Level 1
Fair Value, Inputs, Level 1 [Member]
U.S. Federal research and development credits
Deferred Tax Assets, Tax Credit Carryforwards
Foreign exchange gain / (loss)
Gain (Loss), Foreign Currency Transaction, before Tax
Development and regulatory milestones payment per licensed compound series, maximum
License Agreement Maximum Development And Regulatory Milestone Payments Per License
License Agreement, Maximum Development and Regulatory Milestone Payments Per License
Deferred license revenue, current
Deferred Revenue, Current
Related Party Transaction [Table]
Related Party Transaction [Table]
Diluted (in USD per share)
Diluted net loss attributable to common shareholders per share (in USD per share)
Earnings Per Share, Diluted
Other
Effective Income Tax Rate Reconciliation, Tax Credit, Other, Amount
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Title of 12(b) Security
Title of 12(b) Security
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Other
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Amount
Service, Other
Service, Other [Member]
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Number of shares issued under agreement
Sale of Stock, Number of Shares Issued in Transaction
Arbutus Inc.
Arbutus Inc. [Member]
Arbutus Inc. [Member]
Loss per share
Earnings Per Share [Abstract]
Restructuring Plan [Axis]
Restructuring Plan [Axis]
2030
Lessee, Operating Lease, Liability, to be Paid, Year Five
Total other income
Nonoperating Income (Expense)
Investments, Debt and Equity Securities [Abstract]
Investments, Debt and Equity Securities [Abstract]
Auditor Location
Auditor Location
Blumberg and Drexel
Blumberg and Drexel [Member]
Blumberg and Drexel [Member]
Investment in Genevant
Equity Method Investments and Joint Ventures Disclosure [Text Block]
Research and development
Share-Based Compensation Expense Allocation, Research And Development [Member]
Share-Based Compensation Expense Allocation, Research And Development
Comprehensive loss
Comprehensive Income, Policy [Policy Text Block]
Federal
Domestic Tax Jurisdiction [Member]
Less: interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Other segment expense
Other segment expense
Other segment expense
Tax Credit Carryforward [Axis]
Tax Credit Carryforward [Axis]
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Options exercised - Weighted average exercise price (in CAD and USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Barinthus
Barinthus [Member]
Barinthus
Issuance of common shares pursuant to the Open Market Sales Agreement (in shares)
Stock Issued During Period, Shares, New Issues, Open Market Sale Agreement
Stock Issued During Period, Shares, New Issues, Open Market Sale Agreement
Award Timing Disclosures [Line Items]
Options granted - Weighted average exercise price (in CAD and USD per share)
Options granted - Weighted average exercise price (in CAD and USD per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Qilu Pharmaceutical Co., Ltd.
Qilu Pharmaceutical Co, LTD. [Member]
Qilu Pharmaceutical Co, LTD.
Fair Value, Measurement Frequency [Domain]
Measurement Frequency [Domain]
Property and equipment
Property, Plant and Equipment Disclosure [Text Block]
Total lease payments
Lessee, Operating Lease, Liability, to be Paid
Issuance of common shares pursuant to exercise of options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Exercised
Other early research and development programs expense
Other Research and Development Expense
Shareholders' equity
Equity [Text Block]
Liability related to sale of future royalties
Net liability related to sale of future royalties - beginning balance
Net liability related to sale of future royalties - ending balance
Liability Related To Sale Of Future Royalties, Noncurrent
Liability Related To Sale Of Future Royalties, Noncurrent
Naftzger Plan
Naftzger Plan [Member]
Naftzger Plan
Registration Statement [Domain]
Registration Statement [Domain]
Registration Statement [Domain]
Net loss
Net loss
Consolidated net loss
Net Income (Loss) Attributable to Parent
Subsequent Event [Table]
Subsequent Event [Table]
Expiration Date
Trading Arrangement Expiration Date
Pending Litigation
Pending Litigation [Member]
Restructuring
Restructuring, Impairment, and Other Activities Disclosure [Text Block]
Other liabilities
Increase (Decrease) in Other Operating Liabilities
Schedule of effective income tax rate reconciliation
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Option vesting period (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Property and equipment, net of accumulated depreciation and impairment
Net book value
Property, Plant and Equipment, Net
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Restructuring costs
Restructuring Charges
Adoption Date
Trading Arrangement Adoption Date
Payment (in $000s)
Business Combination, Contingent Consideration, Range of Outcomes, Maximum, Amount
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Accounts receivable
Increase (Decrease) in Accounts Receivable
Tax abatement
Effective Income Tax Rate Reconciliation, Tax Abatement, Percent
Effective Income Tax Rate Reconciliation, Tax Abatement, Percent
Restructuring Cost [Table]
Restructuring Cost [Table]
Components of Deferred Tax Assets [Table]
Tax Credit Carryforward [Table]
Entity Current Reporting Status
Entity Current Reporting Status
General and administrative
Share-Based Compensation Expense Allocation, General And Administrative Expense [Member]
Share-Based Compensation Expense Allocation, General And Administrative Expense
Moderna V. Genevant's And Arbutus' LNP Delivery Technology
Moderna V. Genevant's And Arbutus' LNP Delivery Technology [Member]
Moderna V. Genevant's And Arbutus' LNP Delivery Technology
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Percent of costs related to collaboration
Percent of Costs related to Collaboration
Percent of Costs related to Collaboration
Loss from operations
Operating Income (Loss)
Deficit
Retained Earnings (Accumulated Deficit)
Non-cash impairment of leasehold improvements and laboratory equipment
Leaseholds and Leasehold Improvements [Member]
Computed taxes (benefits) at Canadian federal and provincial tax rates
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Gain on sale of property and equipment
Gain on sale of property and equipment
Gain (Loss) on Disposition of Property Plant Equipment
Financial Instrument [Axis]
Financial Instrument [Axis]
Non-cash items:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Executive Category:
Executive Category [Axis]
Non-taxable and non-deductible items: stock options
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Provincial tax
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Stock-based compensation expense related to ESPP (less than)
Employee Stock Ownership Plan (ESOP), Compensation Expense
Plan modification cost
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
Class of Stock [Axis]
Class of Stock [Axis]
Current Fiscal Year End Date
Current Fiscal Year End Date
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Expected life (in years)
Expected average option term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Payables and Accruals [Abstract]
Payables and Accruals [Abstract]
Weighted-Average Grant-Date Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Statement [Table]
Statement [Table]
Number of positions eliminated
Restructuring and Related Cost, Number of Positions Eliminated
Sub-licensing revenue, percentage
Sub-licensing revenue Percentage
Sub-licensing revenue Percentage
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Collaborations and royalty entitlements
Collaborative Arrangement Disclosure [Text Block]
FINANCING ACTIVITIES
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Shares, Issued, Beginning Balance
Ending balance (in shares)
Shares, Issued
Schedule of assets and liabilities measured at fair value on a recurring basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Anti-dilutive common shares excluded from calculation of income per common share (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Accounts payable and accrued liabilities
Accounts payable and accrued liabilities
Accounts Payable and Accrued Liabilities, Current
Amendment Flag
Amendment Flag
Number of stock-based compensation awards approved to be issued (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Loss before income taxes
Income (Loss) Attributable to Parent, before Tax
Investment tax credits
Deferred Tax Assets, Investments
Leases
Lessee, Operating Leases [Text Block]
Termination Date
Trading Arrangement Termination Date
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Gross proceeds from royalty interest sold
Gross Proceeds From Royalty Interest Sold
Gross Proceeds From Royalty Interest Sold
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Measure:
Measure [Axis]
Weighted average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Schedule of stock option activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Property, Plant and Equipment, Type [Domain]
Long-Lived Tangible Asset [Domain]
Issuance of common shares upon settlement of RSUs
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures
Basic (in shares)
Weighted average number of common shares - basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Director
Director [Member]
Related Party Transaction [Domain]
Related Party Transaction [Domain]
Subsequent Events [Abstract]
Subsequent Events [Abstract]
Segment Reporting [Abstract]
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Other income
Nonoperating Income (Expense) [Abstract]
Entity Tax Identification Number
Entity Tax Identification Number
Grantee Status [Axis]
Grantee Status [Axis]
Operating expenses
Costs and Expenses [Abstract]
Deferred Income, Revenue Recognized
Deferred Income, Revenue Recognized
Income Tax Authority, Name [Axis]
Income Tax Authority, Name [Axis]
Enantigen's Selling Shareholders
Enantigen's Selling Shareholders [Member]
Enantigen's Selling Shareholders
Contingencies and Commitments [Table]
Contingencies and Commitments [Table]
Balance - Weighted average exercise price (in CAD and USD per share)
Balance - Weighted average exercise price (in CAD and USD per share)
Options outstanding, Weighted average exercise price (in USD per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Trade accounts payable
Accounts Payable, Trade, Current
Restructuring and Related Activities [Abstract]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Directors and Executives
Directors And Executives [Member]
Directors And Executives
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Common shares, shares issued (in shares)
Common Stock, Shares, Issued
Weighted-average remaining lease term (years)
Operating Lease, Weighted Average Remaining Lease Term
Options granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Enantigen
Enantigen [Member]
Enantigen
Royalties from sales of ONPATTRO
Onpattro - Non-cash Royalty [Member]
Onpattro - Non-cash Royalty
Use of estimates
Use of Estimates, Policy [Policy Text Block]
Entity Public Float
Entity Public Float
Interest expense
Interest Expense, Nonoperating
Trading Arrangement:
Trading Arrangement [Axis]
Total Shareholder Return Amount
Total Shareholder Return Amount
Enantigen Therapeutics, Inc
Enantigen Therapeutics, Inc [Member]
Enantigen Therapeutics, Inc
Number of options outstanding (in shares)
Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding
Subsequent events
Subsequent Events [Text Block]
Insider Trading Arrangements [Line Items]
Security Exchange Name
Security Exchange Name
Number
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward]
Jefferies LLC
Jefferies LLC [Member]
Jefferies LLC
Total liabilities
Liabilities
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Sale Agreement
Open Market Sale Agreement [Member]
Open Market Sale Agreement
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Number of royalty entitlements
Alnylam Entitlements
Alnylam Entitlements
Tax abatement
Effective Income Tax Rate Reconciliation, Tax Abatement, Amount
Effective Income Tax Rate Reconciliation, Tax Abatement, Amount
Amortization
Deferred Tax Assets, Tax Deferred Expense, Other
Book amortization in excess of tax
Book amortization in excess of tax
Represents the deferred tax asset book amortization in excess of tax.
Statement [Line Items]
Statement [Line Items]
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Cash and cash equivalents
Cash and Cash Equivalent
Fair Value Measurement Inputs and Valuation Techniques [Table]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Counterparty Name [Axis]
Counterparty Name [Axis]
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Research tax credit carryforward
Research Tax Credit Carryforward [Member]
Number of additional shares authorized (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Corporate Headquarters Located 701 Veterans Circle, Warminster, Pennsylvania
Corporate Headquarters Located 701 Veterans Circle, Warminster, Pennsylvania [Member]
Corporate Headquarters Located 701 Veterans Circle, Warminster, Pennsylvania
Common Shares
Common Stock [Member]
Fair Value
Debt Securities, Available-for-Sale
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name [Domain]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Non-NEOs
Non-NEOs [Member]
(Decrease) / increase in cash and cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Professional fee accruals
Accrued Professional Fees, Current