

<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilities" xlink:href="abus-20180331.xsd#AccountsPayableAndAccruedLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilitiesDetails" xlink:href="abus-20180331.xsd#AccountsPayableAndAccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilitiesTables" xlink:href="abus-20180331.xsd#AccountsPayableAndAccruedLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreements" xlink:href="abus-20180331.xsd#CollaborationsContractsAndLicensingAgreements" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:href="abus-20180331.xsd#CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:href="abus-20180331.xsd#CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsTables" xlink:href="abus-20180331.xsd#CollaborationsContractsAndLicensingAgreementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ConcentrationsOfCreditRisk" xlink:href="abus-20180331.xsd#ConcentrationsOfCreditRisk" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ConcentrationsOfCreditRiskDetails" xlink:href="abus-20180331.xsd#ConcentrationsOfCreditRiskDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CondensedConsolidatedBalanceSheets" xlink:href="abus-20180331.xsd#CondensedConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:href="abus-20180331.xsd#CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CondensedConsolidatedStatementOfStockholdersEquity" xlink:href="abus-20180331.xsd#CondensedConsolidatedStatementOfStockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/CondensedConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:href="abus-20180331.xsd#CondensedConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ConsolidatedStatementsOfCashFlow" xlink:href="abus-20180331.xsd#ConsolidatedStatementsOfCashFlow" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ContingenciesAndCommitments" xlink:href="abus-20180331.xsd#ContingenciesAndCommitments" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ContingenciesAndCommitmentsDetails" xlink:href="abus-20180331.xsd#ContingenciesAndCommitmentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/DocumentAndEntityInformation" xlink:href="abus-20180331.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/IntangibleAssetsAndGoodwill" xlink:href="abus-20180331.xsd#IntangibleAssetsAndGoodwill" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillNarrativeDetails" xlink:href="abus-20180331.xsd#IntangibleAssetsAndGoodwillNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:href="abus-20180331.xsd#IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillTables" xlink:href="abus-20180331.xsd#IntangibleAssetsAndGoodwillTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/LoanPayable" xlink:href="abus-20180331.xsd#LoanPayable" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/LoanPayableDetails" xlink:href="abus-20180331.xsd#LoanPayableDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/LoanPayableTables" xlink:href="abus-20180331.xsd#LoanPayableTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/NatureOfBusinessAndFutureOperations" xlink:href="abus-20180331.xsd#NatureOfBusinessAndFutureOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ShareCapital" xlink:href="abus-20180331.xsd#ShareCapital" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/ShareCapitalDetails" xlink:href="abus-20180331.xsd#ShareCapitalDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPolicies" xlink:href="abus-20180331.xsd#SignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesChangesInFairValueOfContingentConsiderationDetails" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesChangesInFairValueOfContingentConsiderationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesChangesInFairValueOfLiabilityClassifiedStockOptionsDetails" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesChangesInFairValueOfLiabilityClassifiedStockOptionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesNarrativeDetails" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesPolicies" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SignificantAccountingPoliciesTables" xlink:href="abus-20180331.xsd#SignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SiteConsolidationDetails" xlink:href="abus-20180331.xsd#SiteConsolidationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SiteConsolidationNotes" xlink:href="abus-20180331.xsd#SiteConsolidationNotes" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SiteConsolidationTables" xlink:href="abus-20180331.xsd#SiteConsolidationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SubsequentEvents" xlink:href="abus-20180331.xsd#SubsequentEvents" xlink:type="simple" />
  <link:roleRef roleURI="http://arbutusbio.com/role/SubsequentEventsDetails" xlink:href="abus-20180331.xsd#SubsequentEventsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilities" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_5D396869F87C59859D1DFE2F8EFAB65E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_96D754CE36E55DAEB61F7300CE6888AC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_5D396869F87C59859D1DFE2F8EFAB65E" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_96D754CE36E55DAEB61F7300CE6888AC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsPayableTradeCurrent" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_3DC2802DF1325551AACA67AA9B430822" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_3DC2802DF1325551AACA67AA9B430822" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AccruedResearchAndDevelopment" xlink:label="loc_abus_AccruedResearchAndDevelopment_FE317E9466785CBEBCCE5BDE8C17178A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_abus_AccruedResearchAndDevelopment_FE317E9466785CBEBCCE5BDE8C17178A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccruedProfessionalFeesCurrent" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_112C847CBA19500A8C6E6DC5F1EFCF40" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_112C847CBA19500A8C6E6DC5F1EFCF40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LeaseIncentivePayableCurrent" xlink:label="loc_us-gaap_LeaseIncentivePayableCurrent_714973850FC05B9690E92B461097F8D1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_us-gaap_LeaseIncentivePayableCurrent_714973850FC05B9690E92B461097F8D1" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AccruedPayrollCurrent" xlink:label="loc_abus_AccruedPayrollCurrent_4AA9BEFA34EC5849B32CCFAD4CDF0C98" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_abus_AccruedPayrollCurrent_4AA9BEFA34EC5849B32CCFAD4CDF0C98" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_68A6B6D44EC6504196840DC2B503131F" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_68A6B6D44EC6504196840DC2B503131F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_CBD91698156D5D489CD1EC1663776889" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_36DDA760EC7853F698023C27CBBEADE1" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_CBD91698156D5D489CD1EC1663776889" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/AccountsPayableAndAccruedLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_19E0F8D6D9705EFD8F5BE512EE2B744E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_98B96C81F205524CB1B1ED7FFFBCBE04" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_19E0F8D6D9705EFD8F5BE512EE2B744E" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_98B96C81F205524CB1B1ED7FFFBCBE04" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueDisclosureAbstract" xlink:label="loc_us-gaap_DeferredRevenueDisclosureAbstract_A65E8925E0D75360B20F969DC2BB1FBD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_01CCD1043A955B7F888EF1C28020C5FE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredRevenueDisclosureAbstract_A65E8925E0D75360B20F969DC2BB1FBD" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_01CCD1043A955B7F888EF1C28020C5FE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueDisclosureAbstract" xlink:label="loc_us-gaap_DeferredRevenueDisclosureAbstract_14B6FFB9F61EAE1100872269112F688D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable" xlink:label="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_62E218105F81CA1CA74B2269112F9827" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredRevenueDisclosureAbstract_14B6FFB9F61EAE1100872269112F688D" xlink:to="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_62E218105F81CA1CA74B2269112F9827" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_EC7582E089632F7691472269112FAC89" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_62E218105F81CA1CA74B2269112F9827" xlink:to="loc_us-gaap_CounterpartyNameAxis_EC7582E089632F7691472269112FAC89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CounterpartyNameAxis_EC7582E089632F7691472269112FAC89" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AlexionMember" xlink:label="loc_abus_AlexionMember_13039BDFFFD8C72667592269112F4F99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:to="loc_abus_AlexionMember_13039BDFFFD8C72667592269112F4F99" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_GritstoneMember" xlink:label="loc_abus_GritstoneMember_FEAA4D38E913596B8C832295EF3C7710" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:to="loc_abus_GritstoneMember_FEAA4D38E913596B8C832295EF3C7710" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_TalonTherapeuticsMember" xlink:label="loc_abus_TalonTherapeuticsMember_137636B9B2534FF69DE22269112FCB32" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:to="loc_abus_TalonTherapeuticsMember_137636B9B2534FF69DE22269112FCB32" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_MarqiboMember" xlink:label="loc_abus_MarqiboMember_3AE763C110DBAB346A992269112FCE55" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_9E77E0A41F91BC6CB03E2269112F2510" xlink:to="loc_abus_MarqiboMember_3AE763C110DBAB346A992269112FCE55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_198F03EF9EF78B8BBCE12269112F590A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_62E218105F81CA1CA74B2269112F9827" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_198F03EF9EF78B8BBCE12269112F590A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_82AD5F92C9AF9D09251E2269112FC456" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_198F03EF9EF78B8BBCE12269112F590A" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_82AD5F92C9AF9D09251E2269112FC456" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_MarqiboCommercialSalesMember" xlink:label="loc_abus_MarqiboCommercialSalesMember_BFCFA3962D488EF2843C2269112F5DF0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_82AD5F92C9AF9D09251E2269112FC456" xlink:to="loc_abus_MarqiboCommercialSalesMember_BFCFA3962D488EF2843C2269112F5DF0" xlink:type="arc" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_82AD5F92C9AF9D09251E2269112FC456" xlink:to="loc_abus_MarqiboMember_3AE763C110DBAB346A992269112FCE55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_62E218105F81CA1CA74B2269112F9827" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_LicenseUpfrontPayment" xlink:label="loc_abus_LicenseUpfrontPayment_07CD2CABCF51EA342315226911300560" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_abus_LicenseUpfrontPayment_07CD2CABCF51EA342315226911300560" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="loc_us-gaap_DeferredRevenueCurrent_3F3FC3D18AE17CD04F492295EF179F16" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_us-gaap_DeferredRevenueCurrent_3F3FC3D18AE17CD04F492295EF179F16" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueRevenueRecognized1" xlink:label="loc_us-gaap_DeferredRevenueRevenueRecognized1_50A88B75F74AD486B8A92294762C061E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_us-gaap_DeferredRevenueRevenueRecognized1_50A88B75F74AD486B8A92294762C061E" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_NumberOfChemotherapyProductsWithWorldwideLicenses" xlink:label="loc_abus_NumberOfChemotherapyProductsWithWorldwideLicenses_B62B1237C2A5EC3CB37B226911301C89" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_abus_NumberOfChemotherapyProductsWithWorldwideLicenses_B62B1237C2A5EC3CB37B226911301C89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ContractsRevenue" xlink:label="loc_us-gaap_ContractsRevenue_EC8826846ABEC41DA5D122691130C5DE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_us-gaap_ContractsRevenue_EC8826846ABEC41DA5D122691130C5DE" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_PotentialContractFundingAmount" xlink:label="loc_abus_PotentialContractFundingAmount_590810CE62B46E78492D22691130A6A1" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_abus_PotentialContractFundingAmount_590810CE62B46E78492D22691130A6A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RoyaltyRevenue" xlink:label="loc_us-gaap_RoyaltyRevenue_7ECEBBDB78D2A50D7D7B2269113088C3" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_us-gaap_RoyaltyRevenue_7ECEBBDB78D2A50D7D7B2269113088C3" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AccruedContractRevenuePercentage" xlink:label="loc_abus_AccruedContractRevenuePercentage_443A082A39AC05247B85226911307B82" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_1A1AC83613982B5D355422691130384E" xlink:to="loc_abus_AccruedContractRevenuePercentage_443A082A39AC05247B85226911307B82" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueDisclosureAbstract" xlink:label="loc_us-gaap_DeferredRevenueDisclosureAbstract_D4D57A068B7C2BF636F722691134DDC4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_76200552D06464C74ECF226911347074" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredRevenueDisclosureAbstract_D4D57A068B7C2BF636F722691134DDC4" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_76200552D06464C74ECF226911347074" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_379125D7314A03B2064E226911342972" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_76200552D06464C74ECF226911347074" xlink:to="loc_us-gaap_CounterpartyNameAxis_379125D7314A03B2064E226911342972" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CounterpartyNameAxis_379125D7314A03B2064E226911342972" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AlexionMember" xlink:label="loc_abus_AlexionMember_305C04E9A885029428CE2269113422C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:to="loc_abus_AlexionMember_305C04E9A885029428CE2269113422C4" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_GritstoneMember" xlink:label="loc_abus_GritstoneMember_911AE801D69189C5A37322691134413C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:to="loc_abus_GritstoneMember_911AE801D69189C5A37322691134413C" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_OtherMilestoneandRoyaltyPaymentsMember" xlink:label="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_5156CF4F685AACF8E575226911344456" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:to="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_5156CF4F685AACF8E575226911344456" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_DoDMember" xlink:label="loc_abus_DoDMember_8C1D7AE978CAC2BEA92F226911342063" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_F83113D78D1D1CB1ADE822691134764B" xlink:to="loc_abus_DoDMember_8C1D7AE978CAC2BEA92F226911342063" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_76200552D06464C74ECF226911347074" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ContractsRevenue" xlink:label="loc_us-gaap_ContractsRevenue_DD7E531483CD0D8A71412269113454F6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:to="loc_us-gaap_ContractsRevenue_DD7E531483CD0D8A71412269113454F6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LicensesRevenue" xlink:label="loc_us-gaap_LicensesRevenue_3E35A0CC58DDD84CC05522691134CDC7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:to="loc_us-gaap_LicensesRevenue_3E35A0CC58DDD84CC05522691134CDC7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_EDEED029B3C9AD5C505722691134FBF5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:to="loc_us-gaap_Revenues_EDEED029B3C9AD5C505722691134FBF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="loc_us-gaap_DeferredRevenueCurrent_3A6484C6E7381293928B22691134C46D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:to="loc_us-gaap_DeferredRevenueCurrent_3A6484C6E7381293928B22691134C46D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenue" xlink:label="loc_us-gaap_DeferredRevenue_B6FEB5B042387218E35B22691134278F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_A35F7B1E64ED6F39FF9F22691134DD7F" xlink:to="loc_us-gaap_DeferredRevenue_B6FEB5B042387218E35B22691134278F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CollaborationsContractsAndLicensingAgreementsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueDisclosureAbstract" xlink:label="loc_us-gaap_DeferredRevenueDisclosureAbstract_2B8AB30B8E5E64ACDFEB18A51C78F04B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock_710B77E841885291829B18A51C781B45" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredRevenueDisclosureAbstract_2B8AB30B8E5E64ACDFEB18A51C78F04B" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock_710B77E841885291829B18A51C781B45" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueByArrangementDisclosureTextBlock" xlink:label="loc_us-gaap_DeferredRevenueByArrangementDisclosureTextBlock_131F184E0269692350E418A5C24DB8D5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DeferredRevenueDisclosureAbstract_2B8AB30B8E5E64ACDFEB18A51C78F04B" xlink:to="loc_us-gaap_DeferredRevenueByArrangementDisclosureTextBlock_131F184E0269692350E418A5C24DB8D5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ConcentrationsOfCreditRisk" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_5B27583EB42651A5AAC3052A00A48B33" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ConcentrationRiskDisclosureTextBlock" xlink:label="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_430F608C2AD85BB28489A6457B43F829" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_5B27583EB42651A5AAC3052A00A48B33" xlink:to="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_430F608C2AD85BB28489A6457B43F829" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ConcentrationsOfCreditRiskDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_71432198E4615ECFAE7F8735BE740C0E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsReceivableNet" xlink:label="loc_us-gaap_AccountsReceivableNet_1177A65CAA525F9AA627551F55FD7E4C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_71432198E4615ECFAE7F8735BE740C0E" xlink:to="loc_us-gaap_AccountsReceivableNet_1177A65CAA525F9AA627551F55FD7E4C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_A702628E733C95B1B7D82268EDCC702C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_A702628E733C95B1B7D82268EDCC702C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ShortTermInvestments" xlink:label="loc_us-gaap_ShortTermInvestments_D5C9EEFA21C38022486E2268EDCDB1C9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_ShortTermInvestments_D5C9EEFA21C38022486E2268EDCDB1C9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_93444D318007CAC6AB012268EDCDF9F2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_93444D318007CAC6AB012268EDCDF9F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_UnbilledReceivablesCurrent" xlink:label="loc_us-gaap_UnbilledReceivablesCurrent_3629B8177E15441105AC2268EDCDEB38" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_UnbilledReceivablesCurrent_3629B8177E15441105AC2268EDCDEB38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaap_IncomeTaxesReceivable_D6943304523224725B2F2268EDCD61DF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_IncomeTaxesReceivable_D6943304523224725B2F2268EDCD61DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_D7EC44489F2F6C8A843B2268EDCD3E99" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_8A5059A23285929E8B552268EDCC6192" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_D7EC44489F2F6C8A843B2268EDCD3E99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_A8CC02EBB01BD516225E2268EDCD61C0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_AssetsCurrent_A8CC02EBB01BD516225E2268EDCD61C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestrictedInvestmentsNoncurrent" xlink:label="loc_us-gaap_RestrictedInvestmentsNoncurrent_587B15F1E77F3A5494B82268EDCD88E5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_RestrictedInvestmentsNoncurrent_587B15F1E77F3A5494B82268EDCD88E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LongTermInvestments" xlink:label="loc_us-gaap_LongTermInvestments_A404C19CFDDA5B65726B2268EDCD1674" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_LongTermInvestments_A404C19CFDDA5B65726B2268EDCD1674" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_F15C38540E26D18674492268EDCD105B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_F15C38540E26D18674492268EDCD105B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_6F9F7F62D031146A1A242268EDCD853D" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_6F9F7F62D031146A1A242268EDCD853D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_7DF1812ECBC9165BA7FB2268EDCD3C82" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_7DF1812ECBC9165BA7FB2268EDCD3C82" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_EBC20ADA27B3207A08C32268EDCD6E95" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_EBC20ADA27B3207A08C32268EDCD6E95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_EF05F6CAD3BA170351152268EDCD6EA6" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_A63C00ED0D0D40B05B8C2268EDCCBAFB" xlink:to="loc_us-gaap_Goodwill_EF05F6CAD3BA170351152268EDCD6EA6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_59237E259A64193623EE2268EDCD6300" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_Assets_59237E259A64193623EE2268EDCD6300" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_C1938BF978B0E9B0C33E2268EDCD7B96" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_C1938BF978B0E9B0C33E2268EDCD7B96" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRevenueCurrent" xlink:label="loc_us-gaap_DeferredRevenueCurrent_34968A5DEFC480E31F022268EDCE5F7C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:to="loc_us-gaap_DeferredRevenueCurrent_34968A5DEFC480E31F022268EDCE5F7C" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstanding" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstanding_D26A8E38C2ACB6F9964B2268EDCE3E12" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstanding_D26A8E38C2ACB6F9964B2268EDCE3E12" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_WarrantsAndRightsOutstanding" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_A87908CE2325C09C3FC52268EDCE31AB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9943A5EE45AC81F380952268EDCD7E9F" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_A87908CE2325C09C3FC52268EDCE31AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_B120499BAB535BBCED142268EDCE8845" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_LiabilitiesCurrent_B120499BAB535BBCED142268EDCE8845" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredRentCreditNoncurrent" xlink:label="loc_us-gaap_DeferredRentCreditNoncurrent_A4DF5558C80E006CA16F2268EDCE3669" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_DeferredRentCreditNoncurrent_A4DF5558C80E006CA16F2268EDCE3669" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LongTermLoansPayable" xlink:label="loc_us-gaap_LongTermLoansPayable_D32BBC1CC4C6320CB53D2268EDCE377C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_LongTermLoansPayable_D32BBC1CC4C6320CB53D2268EDCE377C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_B21AB3D46401460339022268EDCE3EF0" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_B21AB3D46401460339022268EDCE3EF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DeferredTaxLiabilitiesNoncurrent" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesNoncurrent_B56D9A9F1C9BD14B1E2E2268EDCECD38" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_3C2B6CAA2719A9CFDED92268EDCD7C0C" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesNoncurrent_B56D9A9F1C9BD14B1E2E2268EDCECD38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_C2A44B0DD15582F7305F2268EDCE5739" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_Liabilities_C2A44B0DD15582F7305F2268EDCE5739" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount" xlink:label="loc_us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount_7A80CEFF6CFAED731C092268EDCECB4C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount_7A80CEFF6CFAED731C092268EDCECB4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_FA80B378D01F23085A302268EDCECD7B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_CommonStockValue_FA80B378D01F23085A302268EDCECD7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaap_AdditionalPaidInCapital_B5162E4FCF86FCD8525D2268EDCE7A06" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_AdditionalPaidInCapital_B5162E4FCF86FCD8525D2268EDCE7A06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_AC9C73D784D5B06EF7862268EDCEA440" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_AC9C73D784D5B06EF7862268EDCEA440" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_89B8D7BDB6EC300A8FCE2268EDCE2FB2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_89B8D7BDB6EC300A8FCE2268EDCE2FB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_8588AA43ED1B2B72D1E22268EDCE316A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_69EFAF267717A7A7C1FD2268EDCEFF89" xlink:to="loc_us-gaap_StockholdersEquity_8588AA43ED1B2B72D1E22268EDCE316A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_0823A56910674C34C5592268EDCFFC80" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_F458CB53023622C05FDD2268EDCB34E3" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_0823A56910674C34C5592268EDCFFC80" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_60B06E72E3623965675F2275677EFEB9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_60B06E72E3623965675F2275677EFEB9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="loc_us-gaap_PreferredStockSharesIssued_0498588920896B0580D222763620EDED" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_PreferredStockSharesIssued_0498588920896B0580D222763620EDED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_FEF82345094340B351C522768BB35292" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_FEF82345094340B351C522768BB35292" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockNoParValue" xlink:label="loc_us-gaap_CommonStockNoParValue_BDC209A30BBB6CBEE5692268EC9ADC91" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_CommonStockNoParValue_BDC209A30BBB6CBEE5692268EC9ADC91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_15414181258D49B0C42F2268EC9AA390" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_CommonStockSharesIssued_15414181258D49B0C42F2268EC9AA390" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_BA9C65DA5D118096EDF92268EC9A437E" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_0268214E8397ABC429FF2268EC9A62EB" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_BA9C65DA5D118096EDF92268EC9A437E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CondensedConsolidatedStatementOfStockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_370A6B205BDCB8E4026D2269115AC944" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_77C0C47C90B8087A88A42269115AA29C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_370A6B205BDCB8E4026D2269115AC944" xlink:to="loc_us-gaap_StatementTable_77C0C47C90B8087A88A42269115AA29C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_81751A3B8B8F92B4F71A2269115ADD2F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_77C0C47C90B8087A88A42269115AA29C" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_81751A3B8B8F92B4F71A2269115ADD2F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_81751A3B8B8F92B4F71A2269115ADD2F" xlink:to="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="loc_us-gaap_PreferredStockMember_E0A4997023439BB31CA42269115BCFCE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:to="loc_us-gaap_PreferredStockMember_E0A4997023439BB31CA42269115BCFCE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_C95A72ACC8D63E7789112269115A2B48" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:to="loc_us-gaap_CommonStockMember_C95A72ACC8D63E7789112269115A2B48" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_BF48EE902670C38B3FCD2269115B6840" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_BF48EE902670C38B3FCD2269115B6840" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_F9665BAB32F8566A0BB92269115B2644" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:to="loc_us-gaap_RetainedEarningsMember_F9665BAB32F8566A0BB92269115B2644" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_32D43595A97968EBB2442269115B3CA7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_7329771AE3B8C579A6E02269115AFA1F" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_32D43595A97968EBB2442269115B3CA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_77C0C47C90B8087A88A42269115AA29C" xlink:to="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_07352254398CDD668E3A2269115BC8D5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_SharesIssued_07352254398CDD668E3A2269115BC8D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_594156AFB8F80455A03E2269115B0778" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_StockholdersEquity_594156AFB8F80455A03E2269115B0778" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="loc_us-gaap_PreferredStockSharesIssued_BD0D694940DB262C8B412269115B0119" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_PreferredStockSharesIssued_BD0D694940DB262C8B412269115B0119" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaap_PreferredStockValue_2B5475E4AFF536F4C25E2269115B7B8D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_PreferredStockValue_2B5475E4AFF536F4C25E2269115B7B8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockAccretionOfRedemptionDiscount" xlink:label="loc_us-gaap_PreferredStockAccretionOfRedemptionDiscount_13D0EF73E7EEA90D8C182269115B8DA6" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_PreferredStockAccretionOfRedemptionDiscount_13D0EF73E7EEA90D8C182269115B8DA6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_FCF5A056233060355BE12269115B1AD4" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_FCF5A056233060355BE12269115B1AD4" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards" xlink:label="loc_abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards_6FF3088D45726D81718E2269115BAC77" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards_6FF3088D45726D81718E2269115BAC77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_4026B5FE06B5E6DFF3D52269115B75EC" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_4026B5FE06B5E6DFF3D52269115B75EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_85139949EFDC5533316F2269115B031D" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_85139949EFDC5533316F2269115B031D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_51386DAEB38F50AD51C42269115B8EDF" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_NetIncomeLoss_51386DAEB38F50AD51C42269115B8EDF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_503204B3BAA39E19CBDD2269115B1B7B" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_SharesIssued_503204B3BAA39E19CBDD2269115B1B7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_744BCA33BCF4EAACC5BC2269115B5CFC" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_StockholdersEquity_744BCA33BCF4EAACC5BC2269115B5CFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_3280718F668C0867D4142283A67866B1" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_DD97260C75916C810FB82269115B0EAF" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_3280718F668C0867D4142283A67866B1" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/CondensedConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RevenuesAbstract" xlink:label="loc_us-gaap_RevenuesAbstract_436B4071F609A45F52E522D24D56C299" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_RevenuesAbstract_436B4071F609A45F52E522D24D56C299" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_C767642E91B372B6D31422D24D56259B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_436B4071F609A45F52E522D24D56C299" xlink:to="loc_us-gaap_Revenues_C767642E91B372B6D31422D24D56259B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_OperatingExpensesAbstract" xlink:label="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_C76AAECE82762B64857322D24D561A9A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_C76AAECE82762B64857322D24D561A9A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_4A50CCBC35C3B1A6CC9E22D24D567596" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_4A50CCBC35C3B1A6CC9E22D24D567596" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_66291545303F0A65FC5B22D24D563B2D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:to="loc_us-gaap_Depreciation_66291545303F0A65FC5B22D24D563B2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_FADF2341CBEBDBA17ACD22D24D56E9C5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:to="loc_us-gaap_RestructuringCharges_FADF2341CBEBDBA17ACD22D24D56E9C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaap_OperatingExpenses_B1D7470C7B7ED47FB56B22D24D5746F2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_F0F470BEA7C7942A084722D24D561082" xlink:to="loc_us-gaap_OperatingExpenses_B1D7470C7B7ED47FB56B22D24D5746F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_57377F5EA92474252D0D22D24D57149D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_OperatingIncomeLoss_57377F5EA92474252D0D22D24D57149D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_InvestmentIncomeInterest" xlink:label="loc_us-gaap_InvestmentIncomeInterest_4148403BE26AA8E0D89822D24D57F4AF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_InvestmentIncomeInterest_4148403BE26AA8E0D89822D24D57F4AF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_C19D3115EB9F3F9E9C2B22D24D5772F1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_InterestExpense_C19D3115EB9F3F9E9C2B22D24D5772F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_E3F5DA2E2923069FA53622D24D57F215" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_E3F5DA2E2923069FA53622D24D57F215" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueOptionChangesInFairValueGainLoss1" xlink:label="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_FCFFD9EC497164A3AE4822D24D57786A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_FCFFD9EC497164A3AE4822D24D57786A" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability" xlink:label="loc_abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability_E94A169BC1A1DBBFBA2822D24D577B5E" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability_E94A169BC1A1DBBFBA2822D24D577B5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_F19701187E2332450B3A22D24D5786E8" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_F19701187E2332450B3A22D24D5786E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_3EA718688A75AC5B0AA022D24D5794D2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_9FE3C5835262468B377522D24D573654" xlink:to="loc_us-gaap_NetIncomeLoss_3EA718688A75AC5B0AA022D24D5794D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockDividendsAndOtherAdjustments" xlink:label="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_C4DA424D6447402E594022D24D576356" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_C4DA424D6447402E594022D24D576356" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_69ED9E0DAA24CEC9578022D24D571B45" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_69ED9E0DAA24CEC9578022D24D571B45" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="loc_us-gaap_EarningsPerShareAbstract_432BE0E1B97BC245799C22D24D57E92E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_us-gaap_EarningsPerShareAbstract_432BE0E1B97BC245799C22D24D57E92E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_5D1C8F7B328C1D19198622D24D57E3A2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareAbstract_432BE0E1B97BC245799C22D24D57E92E" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_5D1C8F7B328C1D19198622D24D57E3A2" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_WeightedAverageNumberOfCommonSharesAbstract" xlink:label="loc_abus_WeightedAverageNumberOfCommonSharesAbstract_D5779A68F6B6713980CC22D24D575D91" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_82992EBC5DEE3E01C02922D24D5685CF" xlink:to="loc_abus_WeightedAverageNumberOfCommonSharesAbstract_D5779A68F6B6713980CC22D24D575D91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_CFF1B395317A12E349FC22D24D570369" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_WeightedAverageNumberOfCommonSharesAbstract_D5779A68F6B6713980CC22D24D575D91" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_CFF1B395317A12E349FC22D24D570369" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ConsolidatedStatementsOfCashFlow" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_400DA846E425786741F522D24D48D5C8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_FDB2CAF44D698F11A79D22D24D48BAB0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_400DA846E425786741F522D24D48D5C8" xlink:to="loc_us-gaap_StatementTable_FDB2CAF44D698F11A79D22D24D48BAB0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_1649198A295BD1408E3E22D24D48497F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_FDB2CAF44D698F11A79D22D24D48BAB0" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_1649198A295BD1408E3E22D24D48497F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_57409D4CEA555131D82F22D24D489A81" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_1649198A295BD1408E3E22D24D48497F" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_57409D4CEA555131D82F22D24D489A81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_464AEDE756B510866CCD22D24D48C8EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_57409D4CEA555131D82F22D24D489A81" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_464AEDE756B510866CCD22D24D48C8EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_C25021BF91FA482F43B922D24D48836A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_57409D4CEA555131D82F22D24D489A81" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_C25021BF91FA482F43B922D24D48836A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_FDB2CAF44D698F11A79D22D24D48BAB0" xlink:to="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_80B04600B1035ED65C4522D24D489645" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:to="loc_us-gaap_NetIncomeLoss_80B04600B1035ED65C4522D24D489645" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:to="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_99E6BE35E7E0BFE0782622D24D4833B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:to="loc_us-gaap_Depreciation_99E6BE35E7E0BFE0782622D24D4833B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_C19757B11758E5CBBAB722D24D48F066" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:to="loc_us-gaap_ShareBasedCompensation_C19757B11758E5CBBAB722D24D48F066" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossUnrealized" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_37BF96608B7D1A5EA9F322D24D4874E8" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_37BF96608B7D1A5EA9F322D24D4874E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueOptionChangesInFairValueGainLoss1" xlink:label="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_5C378550E556BF1FA94522D24D48A396" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:to="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_5C378550E556BF1FA94522D24D48A396" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_439ED93621FBA74C39E522D24D486A6B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_BB25AEC1746C80916F1D22D24D48E00B" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_439ED93621FBA74C39E522D24D486A6B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_92BD525AE91FFBF65F4322D24D49A2A5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_92BD525AE91FFBF65F4322D24D49A2A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_461A4AB4D4B011A2694222D24D49FCCA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_461A4AB4D4B011A2694222D24D49FCCA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_8DA06F6DA35B5F06066422D24D491FB2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_8DA06F6DA35B5F06066422D24D491FB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_A769B9AD53551F1514EF22D24D493F2A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_A769B9AD53551F1514EF22D24D493F2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredRevenue" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_956FBF48EDA072E6A8EC22D24D496520" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInDeferredRevenue_956FBF48EDA072E6A8EC22D24D496520" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IncreaseDecreaseInRestructuringReserve" xlink:label="loc_us-gaap_IncreaseDecreaseInRestructuringReserve_502412C47C8A39CD212A22D24D490BE2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_07CF1B6C0269D9CCA81C22D24D49986B" xlink:to="loc_us-gaap_IncreaseDecreaseInRestructuringReserve_502412C47C8A39CD212A22D24D490BE2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_203A3148A6D177E4944F22D24D493899" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_B4AEC70089F1561C9D1322D24D48C694" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_203A3148A6D177E4944F22D24D493899" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CF097EA3F5C5881C9D6422D24D491B21" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CF097EA3F5C5881C9D6422D24D491B21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PaymentsForProceedsFromInvestments" xlink:label="loc_us-gaap_PaymentsForProceedsFromInvestments_7FBE37E4DA1A0D969DBB22D24D494AD8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CF097EA3F5C5881C9D6422D24D491B21" xlink:to="loc_us-gaap_PaymentsForProceedsFromInvestments_7FBE37E4DA1A0D969DBB22D24D494AD8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_C71E56A920D94715463C22D24D4903E0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CF097EA3F5C5881C9D6422D24D491B21" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_C71E56A920D94715463C22D24D4903E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9C98A3E66D862F56962522D24D496308" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_CF097EA3F5C5881C9D6422D24D491B21" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9C98A3E66D862F56962522D24D496308" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepaymentsOfNotesPayable" xlink:label="loc_us-gaap_RepaymentsOfNotesPayable_ECCEE86DF93E9AF250F922D24D49442C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:to="loc_us-gaap_RepaymentsOfNotesPayable_ECCEE86DF93E9AF250F922D24D49442C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_6166E2E59206E26C791F22D24D49C83D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_6166E2E59206E26C791F22D24D49C83D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_6C5CAA61FF1B849C599F22D24D49A2B7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_6C5CAA61FF1B849C599F22D24D49A2B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_BF4970E5E08AB4B1898322D24D49BC51" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_BF4970E5E08AB4B1898322D24D49BC51" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_5CA58CA94568B25084D822D24D4AE044" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_BCDCFE5E5D041AD71E0722D24D498A6F" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_5CA58CA94568B25084D822D24D4AE044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_8DAC402BB0C78360F8A822D24D4A9B65" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_8DAC402BB0C78360F8A822D24D4A9B65" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_829514EC63F9A6C8885022D24D4A628D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_829514EC63F9A6C8885022D24D4A628D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_A1E9D78270629026AE5022D24D4AB7D8" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_A1E9D78270629026AE5022D24D4AB7D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_490E8EB3FC5E063EB13C22D24D4A4881" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_490E8EB3FC5E063EB13C22D24D4A4881" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_3EFC57054192571D3E3422D24D4A2F7D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_B1A2914D82FFECC4FC7922D24D4864F6" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_3EFC57054192571D3E3422D24D4A2F7D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_0307EEA1B9DE4B4AA7C222D24D4A253D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_3EFC57054192571D3E3422D24D4A2F7D" xlink:to="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_0307EEA1B9DE4B4AA7C222D24D4A253D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_67DE030E26CF53E8EFEF22D24D4A2B0D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_0307EEA1B9DE4B4AA7C222D24D4A253D" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_67DE030E26CF53E8EFEF22D24D4A2B0D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ContingenciesAndCommitments" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_06559FC593D75F08982A8AB0470C2D6B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_C16C503FFED05469B49E5ADD72CF059A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_06559FC593D75F08982A8AB0470C2D6B" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_C16C503FFED05469B49E5ADD72CF059A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ContingenciesAndCommitmentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_FD0075BDC55356BAA39E6E6744BD4D10" xlink:type="locator" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ContingenciesandCommitmentsTable" xlink:label="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_FD0075BDC55356BAA39E6E6744BD4D10" xlink:to="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProductOrServiceAxis" xlink:label="loc_us-gaap_ProductOrServiceAxis_6F62322AC4175DE5B9ECBB9AFD528C33" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_us-gaap_ProductOrServiceAxis_6F62322AC4175DE5B9ECBB9AFD528C33" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProductsAndServicesDomain" xlink:label="loc_us-gaap_ProductsAndServicesDomain_18F0C21779035D089F2652D05F853848" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductOrServiceAxis_6F62322AC4175DE5B9ECBB9AFD528C33" xlink:to="loc_us-gaap_ProductsAndServicesDomain_18F0C21779035D089F2652D05F853848" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_MarqiboMember" xlink:label="loc_abus_MarqiboMember_A92E115EB1205722B988FFEB3F63B29F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductsAndServicesDomain_18F0C21779035D089F2652D05F853848" xlink:to="loc_abus_MarqiboMember_A92E115EB1205722B988FFEB3F63B29F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_69C6B197989D5BEE99FB097D3FE1149F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_us-gaap_CounterpartyNameAxis_69C6B197989D5BEE99FB097D3FE1149F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_5DC8EBE97CF05603A292B817FDD40750" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CounterpartyNameAxis_69C6B197989D5BEE99FB097D3FE1149F" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_5DC8EBE97CF05603A292B817FDD40750" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_BlumbergandDrexelMember" xlink:label="loc_abus_BlumbergandDrexelMember_4E42ECA3044A5A33AA38A5DC10424DE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_5DC8EBE97CF05603A292B817FDD40750" xlink:to="loc_abus_BlumbergandDrexelMember_4E42ECA3044A5A33AA38A5DC10424DE0" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_BlumbergMember" xlink:label="loc_abus_BlumbergMember_04007A722F025E5CA0AFCE23690E9102" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_5DC8EBE97CF05603A292B817FDD40750" xlink:to="loc_abus_BlumbergMember_04007A722F025E5CA0AFCE23690E9102" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_07B3FD7C919D59379C3FA1C99917F80F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_dei_LegalEntityAxis_07B3FD7C919D59379C3FA1C99917F80F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_AFBACE9699585D768DE7BBE1DC05A527" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_07B3FD7C919D59379C3FA1C99917F80F" xlink:to="loc_dei_EntityDomain_AFBACE9699585D768DE7BBE1DC05A527" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ArbutusInc.Member" xlink:label="loc_abus_ArbutusInc.Member_F47EE74853F35FCBA961B675383E03AC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_AFBACE9699585D768DE7BBE1DC05A527" xlink:to="loc_abus_ArbutusInc.Member_F47EE74853F35FCBA961B675383E03AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_84493EF37C0155CB9F5F85A8689C6FF1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_us-gaap_LitigationCaseAxis_84493EF37C0155CB9F5F85A8689C6FF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_A795684A3AC35843B273132069C02B9F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseAxis_84493EF37C0155CB9F5F85A8689C6FF1" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_A795684A3AC35843B273132069C02B9F" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ArbitrationWithTheUniversityOfBritishColumbiaMember" xlink:label="loc_abus_ArbitrationWithTheUniversityOfBritishColumbiaMember_E262E910656C5527AA150F691799C084" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_A795684A3AC35843B273132069C02B9F" xlink:to="loc_abus_ArbitrationWithTheUniversityOfBritishColumbiaMember_E262E910656C5527AA150F691799C084" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_997E6BFC2BB657AF89633363F7A6BAD1" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_997E6BFC2BB657AF89633363F7A6BAD1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_394554BDE25A537694462C05494CC58B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_997E6BFC2BB657AF89633363F7A6BAD1" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_394554BDE25A537694462C05494CC58B" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EnantigenMember" xlink:label="loc_abus_EnantigenMember_A0545962F994580F8F75EA2458ED90D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_394554BDE25A537694462C05494CC58B" xlink:to="loc_abus_EnantigenMember_A0545962F994580F8F75EA2458ED90D7" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ContingenciesandCommitmentsLineItems" xlink:label="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_D7D568EEF008548BBD9CE8381E46C62F" xlink:to="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_PercentOfCostsFundedByTPC" xlink:label="loc_abus_PercentOfCostsFundedByTPC_B3F8CC8FDE0F52D2AD3177050AA813F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_PercentOfCostsFundedByTPC_B3F8CC8FDE0F52D2AD3177050AA813F4" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_MaximumContributionForProduct" xlink:label="loc_abus_MaximumContributionForProduct_100C826F2D7059B988878B3800F28631" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_MaximumContributionForProduct_100C826F2D7059B988878B3800F28631" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_CumulativeContributionforProduct" xlink:label="loc_abus_CumulativeContributionforProduct_03AFFA8FB372511A90C771EB1F6F6F71" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_CumulativeContributionforProduct_03AFFA8FB372511A90C771EB1F6F6F71" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RoyaltyGuaranteesCommitmentsPercentage" xlink:label="loc_abus_RoyaltyGuaranteesCommitmentsPercentage_ABE9DD7C19BA573E8F6AE6C32E05C7A6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_RoyaltyGuaranteesCommitmentsPercentage_ABE9DD7C19BA573E8F6AE6C32E05C7A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RoyaltyRevenue" xlink:label="loc_us-gaap_RoyaltyRevenue_0F91905463C752BAB714294BFB8AF2CB" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_RoyaltyRevenue_0F91905463C752BAB714294BFB8AF2CB" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RoyaltyPayable" xlink:label="loc_abus_RoyaltyPayable_A499A9AAA4175D55B47A7071FE3BA5A1" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_RoyaltyPayable_A499A9AAA4175D55B47A7071FE3BA5A1" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RoyaltiesPaidOrAccrued" xlink:label="loc_abus_RoyaltiesPaidOrAccrued_ADFCF3FC29F65996B6ED03AF57522AC2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_RoyaltiesPaidOrAccrued_ADFCF3FC29F65996B6ED03AF57522AC2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ContractualObligation" xlink:label="loc_us-gaap_ContractualObligation_045FEB89B31D568D8FBC3A3D0A1106C2" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_ContractualObligation_045FEB89B31D568D8FBC3A3D0A1106C2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LossContingencyDamagesSoughtValue" xlink:label="loc_us-gaap_LossContingencyDamagesSoughtValue_71BED39FFA2E51259CA2C500B3E09509" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_LossContingencyDamagesSoughtValue_71BED39FFA2E51259CA2C500B3E09509" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_Numberoflegalproceedings" xlink:label="loc_abus_Numberoflegalproceedings_DD7F5AF5B7A95455A0CF4891458ECB0E" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_Numberoflegalproceedings_DD7F5AF5B7A95455A0CF4891458ECB0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_0DA677E98336516DA6599090CC27C422" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_0DA677E98336516DA6599090CC27C422" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ProgramsInPreClinicalDevelopment" xlink:label="loc_abus_ProgramsInPreClinicalDevelopment_3DB581A40FE652A788530414E7DCC7E7" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ProgramsInPreClinicalDevelopment_3DB581A40FE652A788530414E7DCC7E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_C6BED36E9D225ADC9C1312C8C9CE85D5" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_C6BED36E9D225ADC9C1312C8C9CE85D5" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_Numberofseriesofcompounds" xlink:label="loc_abus_Numberofseriesofcompounds_2E0B0E6C273051478B5BCC44F4CF5E60" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_Numberofseriesofcompounds_2E0B0E6C273051478B5BCC44F4CF5E60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LicenseCosts" xlink:label="loc_us-gaap_LicenseCosts_2470ABC82935520FAEF63085E3496172" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_us-gaap_LicenseCosts_2470ABC82935520FAEF63085E3496172" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense" xlink:label="loc_abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense_2EF2E641D1265C8C9394E067AB2FBDF7" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense_2EF2E641D1265C8C9394E067AB2FBDF7" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense" xlink:label="loc_abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense_225D52685918586698336F258439BF71" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense_225D52685918586698336F258439BF71" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ContractualObligationAmountOfResearchFundingPerYear" xlink:label="loc_abus_ContractualObligationAmountOfResearchFundingPerYear_DAF7CDD013BC55A5A7000483ED812317" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ContractualObligationAmountOfResearchFundingPerYear_DAF7CDD013BC55A5A7000483ED812317" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingPeriodNumberofRenewableOptions" xlink:label="loc_abus_ResearchFundingPeriodNumberofRenewableOptions_8FFCF7CDAAAA5CE5B6AC9480D06D988D" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingPeriodNumberofRenewableOptions_8FFCF7CDAAAA5CE5B6AC9480D06D988D" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingPeriod" xlink:label="loc_abus_ResearchFundingPeriod_C6CBAE09FA0B55A48EC3BC7EC84B3248" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingPeriod_C6CBAE09FA0B55A48EC3BC7EC84B3248" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingPeriodRenewableOption" xlink:label="loc_abus_ResearchFundingPeriodRenewableOption_A2053EEEDEBB5EA0B19682739AC1893F" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingPeriodRenewableOption_A2053EEEDEBB5EA0B19682739AC1893F" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment_A84D4EE760925863A6C4E05587160007" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment_A84D4EE760925863A6C4E05587160007" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments_9C388A23B3C8541E9FB05D0789352132" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments_9C388A23B3C8541E9FB05D0789352132" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments_0DF2F595EF6B56389D1B1529031CB6B7" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_869C3653C0C8504B9F8AC5E5F14AB9DD" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments_0DF2F595EF6B56389D1B1529031CB6B7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/DocumentAndEntityInformation" xlink:type="extended">
    <link:loc xlink:href="abus-20180331.xsd#abus_DocumentAndEntityInformationAbstract" xlink:label="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_6D447F8ECC375EF8B60577B5F87E62B5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_DocumentType_6D447F8ECC375EF8B60577B5F87E62B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_10E0E44F618E5C89B8E67F8A1A50BB3D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_AmendmentFlag_10E0E44F618E5C89B8E67F8A1A50BB3D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_8B9E8626D2395C90A39762284AF11BAE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_DocumentPeriodEndDate_8B9E8626D2395C90A39762284AF11BAE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_64DABE5F59B55E68B9000834C564065F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_EntityRegistrantName_64DABE5F59B55E68B9000834C564065F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_530F137C6FF35B5A9C9658B04FA561CF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_EntityCentralIndexKey_530F137C6FF35B5A9C9658B04FA561CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_B25A33E872415FC8AC6A99335A23E850" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_CurrentFiscalYearEndDate_B25A33E872415FC8AC6A99335A23E850" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_E28BE03A05D556F1880B08AE42CDA6A2" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_EntityFilerCategory_E28BE03A05D556F1880B08AE42CDA6A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_580A73DF7B7E5107A0C0212FC5923DFB" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_580A73DF7B7E5107A0C0212FC5923DFB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_5A645CFF63CF5B70A0D8E8CDBE537ACF" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_EntityCurrentReportingStatus_5A645CFF63CF5B70A0D8E8CDBE537ACF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_12A5BF62C39B5CC39DA3125200575EA0" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_DocumentFiscalYearFocus_12A5BF62C39B5CC39DA3125200575EA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_F2D2982ABC6755EEB2FCE6C453D58569" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_4072391F45E1508CBE8DF1948E3C3FFA" xlink:to="loc_dei_DocumentFiscalPeriodFocus_F2D2982ABC6755EEB2FCE6C453D58569" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/IntangibleAssetsAndGoodwill" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_E22CAE1F99035F639B4534D9D0546072" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_C52CF386989F5E2AA3DD9E4C474BE29C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_E22CAE1F99035F639B4534D9D0546072" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_C52CF386989F5E2AA3DD9E4C474BE29C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_769C8FC0BD85545FA37C15BC46F20732" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_6A0499A206E654F0A718C54EF65838DE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_769C8FC0BD85545FA37C15BC46F20732" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_6A0499A206E654F0A718C54EF65838DE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_194E0C25A252522A8BBA871955C5116C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_4ABE1D595B145A01B2F1B927FCA144BA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_194E0C25A252522A8BBA871955C5116C" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_4ABE1D595B145A01B2F1B927FCA144BA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_FEF7A163D99758BAA7F1DCBCE91C291B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_4ABE1D595B145A01B2F1B927FCA144BA" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_FEF7A163D99758BAA7F1DCBCE91C291B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_01CE9E67FB725DE194A070881B791B67" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_FEF7A163D99758BAA7F1DCBCE91C291B" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_01CE9E67FB725DE194A070881B791B67" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_InProcessResearchandDevelopmentImmuneModulatorsMember" xlink:label="loc_abus_InProcessResearchandDevelopmentImmuneModulatorsMember_A5312321F8765D4E898BADFDA243A435" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_01CE9E67FB725DE194A070881B791B67" xlink:to="loc_abus_InProcessResearchandDevelopmentImmuneModulatorsMember_A5312321F8765D4E898BADFDA243A435" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_InProcessResearchandDevelopmentAntigenInhibitorsMember" xlink:label="loc_abus_InProcessResearchandDevelopmentAntigenInhibitorsMember_D19BB3604ACE5DA3904EE296C3ABE9B3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_01CE9E67FB725DE194A070881B791B67" xlink:to="loc_abus_InProcessResearchandDevelopmentAntigenInhibitorsMember_D19BB3604ACE5DA3904EE296C3ABE9B3" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_InProcessResearchandDevelopmentcccDNASterilizersMember" xlink:label="loc_abus_InProcessResearchandDevelopmentcccDNASterilizersMember_767153E2437E5D92AEA9E7247295E15B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_01CE9E67FB725DE194A070881B791B67" xlink:to="loc_abus_InProcessResearchandDevelopmentcccDNASterilizersMember_767153E2437E5D92AEA9E7247295E15B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_8677DF622F8E5D568E0A35117487803E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_4ABE1D595B145A01B2F1B927FCA144BA" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_8677DF622F8E5D568E0A35117487803E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F740E7F1669651C5A392DB14E92BFC63" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_8677DF622F8E5D568E0A35117487803E" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_F740E7F1669651C5A392DB14E92BFC63" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/IntangibleAssetsAndGoodwillTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_241ACF3F0F165ACFADD07398A5732E30" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_FE8A234E84CA5D17906DC4D0E42A6634" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_241ACF3F0F165ACFADD07398A5732E30" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_FE8A234E84CA5D17906DC4D0E42A6634" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/LoanPayable" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_E95A2F731672DFB445A82269112448F5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_0B434E6FA37D3D05A55122691124C46C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_E95A2F731672DFB445A82269112448F5" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_0B434E6FA37D3D05A55122691124C46C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/LoanPayableDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_D0EF668FEB524BB825E822BECA47CFFD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_D0EF668FEB524BB825E822BECA47CFFD" xlink:to="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_FC1CD9AE3F2D5B9D543822BECA47B463" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:to="loc_us-gaap_CounterpartyNameAxis_FC1CD9AE3F2D5B9D543822BECA47B463" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_C9A62691BB32ACD6802D22BECA47692D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CounterpartyNameAxis_FC1CD9AE3F2D5B9D543822BECA47B463" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_C9A62691BB32ACD6802D22BECA47692D" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_WellsFargoMember" xlink:label="loc_abus_WellsFargoMember_FE0DE8C4CF61A2B7551222BECA474442" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_C9A62691BB32ACD6802D22BECA47692D" xlink:to="loc_abus_WellsFargoMember_FE0DE8C4CF61A2B7551222BECA474442" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_1FC897337529285FC16F22BECA47A6D2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_1FC897337529285FC16F22BECA47A6D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_1307065AF833F47580B622BECA47B71B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_1FC897337529285FC16F22BECA47A6D2" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_1307065AF833F47580B622BECA47B71B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LoansPayableMember" xlink:label="loc_us-gaap_LoansPayableMember_7C23420E450649C852CD22BECA47D539" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_1307065AF833F47580B622BECA47B71B" xlink:to="loc_us-gaap_LoansPayableMember_7C23420E450649C852CD22BECA47D539" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_A449EDED4773486BFAAA22BECA4750DE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:to="loc_us-gaap_DebtInstrumentAxis_A449EDED4773486BFAAA22BECA4750DE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_DAA0D8E2D2D45118DBC522BECA481473" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_A449EDED4773486BFAAA22BECA4750DE" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_DAA0D8E2D2D45118DBC522BECA481473" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_PromissoryNoteMember" xlink:label="loc_abus_PromissoryNoteMember_637895842D9C332AA06B22BECA482197" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_DAA0D8E2D2D45118DBC522BECA481473" xlink:to="loc_abus_PromissoryNoteMember_637895842D9C332AA06B22BECA482197" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_8B3EE78F81A6F1808F6F22BECA488206" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:to="loc_us-gaap_VariableRateAxis_8B3EE78F81A6F1808F6F22BECA488206" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_FF62310762D22F0F8D6C22BECA48DDD7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_8B3EE78F81A6F1808F6F22BECA488206" xlink:to="loc_us-gaap_VariableRateDomain_FF62310762D22F0F8D6C22BECA48DDD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_07EC2792E810AD69A2A722BECA48493B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_FF62310762D22F0F8D6C22BECA48DDD7" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_07EC2792E810AD69A2A722BECA48493B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_31B1CA62ADAF2FB14D9E22BECA47B5F7" xlink:to="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentTerm" xlink:label="loc_us-gaap_DebtInstrumentTerm_DFEC3E66B5A6D36983F822CC9068581F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:to="loc_us-gaap_DebtInstrumentTerm_DFEC3E66B5A6D36983F822CC9068581F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_E8A7DAE6BD4D3C1CC61422BECA488DFC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_E8A7DAE6BD4D3C1CC61422BECA488DFC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_4B424AD456624FE07EB922BECA48B5F9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_4B424AD456624FE07EB922BECA48B5F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ShortTermInvestments" xlink:label="loc_us-gaap_ShortTermInvestments_7D415CDB45A6FC7E553822BECA480453" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:to="loc_us-gaap_ShortTermInvestments_7D415CDB45A6FC7E553822BECA480453" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RestrictedInvestmentTerm" xlink:label="loc_abus_RestrictedInvestmentTerm_83FBF4E722AD89344CBE22BECA48CA05" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_1618504925D175CB10AC22BECA489524" xlink:to="loc_abus_RestrictedInvestmentTerm_83FBF4E722AD89344CBE22BECA48CA05" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/LoanPayableTables" xlink:type="extended" />
  <link:presentationLink xlink:role="http://arbutusbio.com/role/NatureOfBusinessAndFutureOperations" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_11AD34F9997B5E34B390F6F99FE8CBFE" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NatureOfOperations" xlink:label="loc_us-gaap_NatureOfOperations_BF8D7678C0A85AD894A3680B84BD5E0B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_11AD34F9997B5E34B390F6F99FE8CBFE" xlink:to="loc_us-gaap_NatureOfOperations_BF8D7678C0A85AD894A3680B84BD5E0B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ShareCapital" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_F4F57E0F738ABA4320C722678BB27C07" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_381D87E9906B96D8402422678BB2ACEF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_F4F57E0F738ABA4320C722678BB27C07" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_381D87E9906B96D8402422678BB2ACEF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/ShareCapitalDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_241B3294A33C96C2D5A022BECA579DE8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_DEC2884FE52F9C40525C22BECA57AE04" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_241B3294A33C96C2D5A022BECA579DE8" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_DEC2884FE52F9C40525C22BECA57AE04" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_32A109267C20BEA9E67022BECA570B78" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_DEC2884FE52F9C40525C22BECA57AE04" xlink:to="loc_us-gaap_CounterpartyNameAxis_32A109267C20BEA9E67022BECA570B78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_8285A044F319F28D305C22BECA571B30" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CounterpartyNameAxis_32A109267C20BEA9E67022BECA570B78" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_8285A044F319F28D305C22BECA571B30" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RoivantSciencesLtdMember" xlink:label="loc_abus_RoivantSciencesLtdMember_EBB8377581CA81A63C9622BECA58B17E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_8285A044F319F28D305C22BECA571B30" xlink:to="loc_abus_RoivantSciencesLtdMember_EBB8377581CA81A63C9622BECA58B17E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaap_StatementClassOfStockAxis_E5CA4A00A92AC8278D0622BECA58F2F3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_DEC2884FE52F9C40525C22BECA57AE04" xlink:to="loc_us-gaap_StatementClassOfStockAxis_E5CA4A00A92AC8278D0622BECA58F2F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaap_ClassOfStockDomain_CD7525160562C41487D922BECA587C6F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_E5CA4A00A92AC8278D0622BECA58F2F3" xlink:to="loc_us-gaap_ClassOfStockDomain_CD7525160562C41487D922BECA587C6F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ConvertiblePreferredStockMember" xlink:label="loc_us-gaap_ConvertiblePreferredStockMember_ED019017FA2FF2ABB4F522BECA58BC07" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_CD7525160562C41487D922BECA587C6F" xlink:to="loc_us-gaap_ConvertiblePreferredStockMember_ED019017FA2FF2ABB4F522BECA58BC07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ClassOfStockLineItems" xlink:label="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_DEC2884FE52F9C40525C22BECA57AE04" xlink:to="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_84D8EB80C0292600D27122BECA58293D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_84D8EB80C0292600D27122BECA58293D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2191A5F00F18978A087E22BECA589B46" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_2191A5F00F18978A087E22BECA589B46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockDividendRatePercentage" xlink:label="loc_us-gaap_PreferredStockDividendRatePercentage_37950ACB323C22ECF2BF22BECA58AB07" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_us-gaap_PreferredStockDividendRatePercentage_37950ACB323C22ECF2BF22BECA58AB07" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion" xlink:label="loc_abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion_81709DF8DA9BE2153B1F22BECA585455" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion_81709DF8DA9BE2153B1F22BECA585455" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_NoncontrollingInterestInvestmentCommitmentPeriod" xlink:label="loc_abus_NoncontrollingInterestInvestmentCommitmentPeriod_911688EC1B92AA5FEE1322BECA58308D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_abus_NoncontrollingInterestInvestmentCommitmentPeriod_911688EC1B92AA5FEE1322BECA58308D" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners" xlink:label="loc_abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners_4DCBB4422A183526C7CF22BECA586A4B" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners_4DCBB4422A183526C7CF22BECA586A4B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_1F988A450704D53BA22D22BECA58DBE7" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_D4D66862BF43C94C64CA22BECA58A9D1" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_1F988A450704D53BA22D22BECA58DBE7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_8A25E4BA0B82522B9A2C77876AD3E515" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3021993779885DC7B514F3BC0FB915D9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8A25E4BA0B82522B9A2C77876AD3E515" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_3021993779885DC7B514F3BC0FB915D9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_85375DFE78F7192E191922BECA7C9FD3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable" xlink:label="loc_us-gaap_FairValueByBalanceSheetGroupingTable_F84EB26832B38CE823D922BECA7C7CA1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_85375DFE78F7192E191922BECA7C9FD3" xlink:to="loc_us-gaap_FairValueByBalanceSheetGroupingTable_F84EB26832B38CE823D922BECA7C7CA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_CA37F9BAE8A9AD17C82D22BECA7C56EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_F84EB26832B38CE823D922BECA7C7CA1" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_CA37F9BAE8A9AD17C82D22BECA7C56EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_F8DF6BC9C4C99A24219122BECA7C2FBD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_CA37F9BAE8A9AD17C82D22BECA7C56EA" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_F8DF6BC9C4C99A24219122BECA7C2FBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_CAF5588EC64204389DF222BECA7C32CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_F8DF6BC9C4C99A24219122BECA7C2FBD" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_CAF5588EC64204389DF222BECA7C32CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_AF64BB994D17A83C32A622BECA7C8998" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_F8DF6BC9C4C99A24219122BECA7C2FBD" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_AF64BB994D17A83C32A622BECA7C8998" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:label="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_AA7EE044411CD8F2E4D922BECA7C1C88" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_F84EB26832B38CE823D922BECA7C7CA1" xlink:to="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_AA7EE044411CD8F2E4D922BECA7C1C88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_AA7EE044411CD8F2E4D922BECA7C1C88" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_591E7CC4B5338EACC1F322BECA7CF231" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_591E7CC4B5338EACC1F322BECA7CF231" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_InvestmentsFairValueDisclosure" xlink:label="loc_us-gaap_InvestmentsFairValueDisclosure_B29BBFF3C2176866844222BECA7C5FBD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:to="loc_us-gaap_InvestmentsFairValueDisclosure_B29BBFF3C2176866844222BECA7C5FBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestrictedInvestmentsAtFairValue" xlink:label="loc_us-gaap_RestrictedInvestmentsAtFairValue_2F8C0FCA9EE5F8F606C622BECA7C9CCB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:to="loc_us-gaap_RestrictedInvestmentsAtFairValue_2F8C0FCA9EE5F8F606C622BECA7C9CCB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_D0B582C38C5DBAC3A4FA22BECA7CFABF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_596DA2E41594B71B89B922BECA7C1DD7" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_D0B582C38C5DBAC3A4FA22BECA7CFABF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_AA7EE044411CD8F2E4D922BECA7C1C88" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_2DA61A71E1012550009122BECA7D7C3B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_2DA61A71E1012550009122BECA7D7C3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_20A3FEEC2862947B990E22BECA7D414D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_20A3FEEC2862947B990E22BECA7D414D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_BEF95461F96BF8F80BC922BECA7D49DA" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:to="loc_us-gaap_RestructuringReserve_BEF95461F96BF8F80BC922BECA7D49DA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureRecurring" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureRecurring_F74BC90723750A67276322BECA7D1D28" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_BDE868676C43F1AA2AAE22BECA7C2C35" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureRecurring_F74BC90723750A67276322BECA7D1D28" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesChangesInFairValueOfContingentConsiderationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_193B07BA4AE0132AA76622691142C3F9" xlink:type="locator" />
    <link:loc xlink:href="abus-20180331.xsd#abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward" xlink:label="loc_abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward_4CEA805CD3E82C88C49C22691142A1A9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_193B07BA4AE0132AA76622691142C3F9" xlink:to="loc_abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward_4CEA805CD3E82C88C49C22691142A1A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_48A7982140409F12BDA62269114291CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward_4CEA805CD3E82C88C49C22691142A1A9" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_48A7982140409F12BDA62269114291CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_969137939463FEB6CFA022691142DCCC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward_4CEA805CD3E82C88C49C22691142A1A9" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_969137939463FEB6CFA022691142DCCC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_48EFD6FA125396231EC6226911426FCF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_BusinessCombinationContingentConsiderationArrangementsChangeinAmountofContingentConsiderationFairValueLiabilityRollForward_4CEA805CD3E82C88C49C22691142A1A9" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_48EFD6FA125396231EC6226911426FCF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesChangesInFairValueOfLiabilityClassifiedStockOptionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_8BBF6C0C86FD568C94599F185D09C741" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_B3756A3C265C57B8B26BD48CD16E1A91" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_8BBF6C0C86FD568C94599F185D09C741" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_B3756A3C265C57B8B26BD48CD16E1A91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_CF3338EEE45154179DCC62EB143AAA25" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_B3756A3C265C57B8B26BD48CD16E1A91" xlink:to="loc_us-gaap_AwardTypeAxis_CF3338EEE45154179DCC62EB143AAA25" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1E36C0E3E3E4516D97AAF9BEF4619B5E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_CF3338EEE45154179DCC62EB143AAA25" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1E36C0E3E3E4516D97AAF9BEF4619B5E" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_9FEBB5BF19BA5C29AC910B4273AEB860" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1E36C0E3E3E4516D97AAF9BEF4619B5E" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_9FEBB5BF19BA5C29AC910B4273AEB860" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D57FD351A58B5CE28A35813FE4BCD8DB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_B3756A3C265C57B8B26BD48CD16E1A91" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D57FD351A58B5CE28A35813FE4BCD8DB" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward" xlink:label="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_D57FD351A58B5CE28A35813FE4BCD8DB" xlink:to="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_5887721222DA542B8D3A0F97AA596FCB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_5887721222DA542B8D3A0F97AA596FCB" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_FairValueofLiabilityOptionsExercisedInThePeriod" xlink:label="loc_abus_FairValueofLiabilityOptionsExercisedInThePeriod_0BE15D2F58D053DABDDD128D7501B6F7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:to="loc_abus_FairValueofLiabilityOptionsExercisedInThePeriod_0BE15D2F58D053DABDDD128D7501B6F7" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions" xlink:label="loc_abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions_3345890651595085B7AA03FBA9344395" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:to="loc_abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions_3345890651595085B7AA03FBA9344395" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_39B0C3185B1355B9AA4D9892701FAB4A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_F13D048B94B9587FB121395238C19827" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_39B0C3185B1355B9AA4D9892701FAB4A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_6085DF4265D889E2734822AC6AAAF268" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_5721D83598D3368368A222AC6AABEBA5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6085DF4265D889E2734822AC6AAAF268" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_5721D83598D3368368A222AC6AABEBA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaap_StatementClassOfStockAxis_9EEC89E5528213D20B9E22AC6AAB70F3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_5721D83598D3368368A222AC6AABEBA5" xlink:to="loc_us-gaap_StatementClassOfStockAxis_9EEC89E5528213D20B9E22AC6AAB70F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaap_ClassOfStockDomain_5C17E08DC4480CB4E46322AC6AABA041" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_9EEC89E5528213D20B9E22AC6AAB70F3" xlink:to="loc_us-gaap_ClassOfStockDomain_5C17E08DC4480CB4E46322AC6AABA041" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_8E10667AD25F0FCB714922AC6AB1A28F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_5C17E08DC4480CB4E46322AC6AABA041" xlink:to="loc_us-gaap_CommonStockMember_8E10667AD25F0FCB714922AC6AB1A28F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="loc_us-gaap_PreferredStockMember_7F7CA0596EE8A42AB8FE22AC6AB1980B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_5C17E08DC4480CB4E46322AC6AABA041" xlink:to="loc_us-gaap_PreferredStockMember_7F7CA0596EE8A42AB8FE22AC6AB1980B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EarningsPerShareBasicLineItems" xlink:label="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_5721D83598D3368368A222AC6AABEBA5" xlink:to="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements" xlink:label="loc_abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements_A16269990D8D0550301C22AC6AB27390" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements_A16269990D8D0550301C22AC6AB27390" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_3E0FD4189B0E6BA9788822AC6AB2852E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_3E0FD4189B0E6BA9788822AC6AB2852E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PreferredStockDividendsAndOtherAdjustments" xlink:label="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_4A1A3F9B443B041B621D22AC6AB2B6B9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_4A1A3F9B443B041B621D22AC6AB2B6B9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_0A0AE39E1C385DD8644D22AC6AB2F90F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_0A0AE39E1C385DD8644D22AC6AB2F90F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_095C45155989F69C421C22AC6AB2B1B7" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_095C45155989F69C421C22AC6AB2B1B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_3BA776ADEBA14D07D05722AC6AB2ADE4" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_BFBC448FEDD243E5920E22AC6AB12CD8" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_3BA776ADEBA14D07D05722AC6AB2ADE4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_FF1A8D970E2C1E54318E22691154634F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_FF1A8D970E2C1E54318E22691154634F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_5AE5AF83DBFEB16DD67C226911542EF6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_5AE5AF83DBFEB16DD67C226911542EF6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_16FF00D8DA13FEAF685B226911547C69" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_16FF00D8DA13FEAF685B226911547C69" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_950B858761A0C2AE9B8C226911548C48" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_950B858761A0C2AE9B8C226911548C48" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock" xlink:label="loc_us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock_44B45F71673A229B7EFC22691154E15D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_CostsAssociatedWithExitOrDisposalActivitiesOrRestructuringsPolicyTextBlock_44B45F71673A229B7EFC22691154E15D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_80EB6398C7624C0E3A0822691154E9F2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_FE46E8E2AA32B0C4A85E2269115461C4" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_80EB6398C7624C0E3A0822691154E9F2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_806F57A927797316CE581D7953E53894" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_025553A604580F17CB5C1D80E7C83050" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_806F57A927797316CE581D7953E53894" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_025553A604580F17CB5C1D80E7C83050" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_F18D76D50434AA1785401D7953E57C89" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_806F57A927797316CE581D7953E53894" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_F18D76D50434AA1785401D7953E57C89" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_ChangesInFairValueofLiabilityOptionTableTextBlock" xlink:label="loc_abus_ChangesInFairValueofLiabilityOptionTableTextBlock_47FAA8475734C0200C851D7953E5BA5B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_806F57A927797316CE581D7953E53894" xlink:to="loc_abus_ChangesInFairValueofLiabilityOptionTableTextBlock_47FAA8475734C0200C851D7953E5BA5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_BF8143B6F6EC386DE8411D7953E6E4D9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_806F57A927797316CE581D7953E53894" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_BF8143B6F6EC386DE8411D7953E6E4D9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SiteConsolidationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6B745B600E85B1B3EA371DA8A31FAE84" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_E950BE395F9E798F6E4D1DAB9674F190" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6B745B600E85B1B3EA371DA8A31FAE84" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_E950BE395F9E798F6E4D1DAB9674F190" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_F8AE762FE0C24C2AF1FF1DAB967CA4DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_E950BE395F9E798F6E4D1DAB9674F190" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_F8AE762FE0C24C2AF1FF1DAB967CA4DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_F8AE762FE0C24C2AF1FF1DAB967CA4DD" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_FacilityClosingMember" xlink:label="loc_us-gaap_FacilityClosingMember_EE48578E47A075BD59091DACB04A2C7A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:to="loc_us-gaap_FacilityClosingMember_EE48578E47A075BD59091DACB04A2C7A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EmployeeSeveranceMember" xlink:label="loc_us-gaap_EmployeeSeveranceMember_675DEEB654054D76058F1DB1665B2A44" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:to="loc_us-gaap_EmployeeSeveranceMember_675DEEB654054D76058F1DB1665B2A44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EmployeeRelocationMember" xlink:label="loc_us-gaap_EmployeeRelocationMember_0AFFE5707E0C538B2E4E1DB6F76CC29E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:to="loc_us-gaap_EmployeeRelocationMember_0AFFE5707E0C538B2E4E1DB6F76CC29E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ContractTerminationMember" xlink:label="loc_us-gaap_ContractTerminationMember_5CED7DA16BFB965C17971DB255E40B0B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_2361D14DAC954CA4FB161DAB967E0E80" xlink:to="loc_us-gaap_ContractTerminationMember_5CED7DA16BFB965C17971DB255E40B0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_E950BE395F9E798F6E4D1DAB9674F190" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent" xlink:label="loc_abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent_876A98134F8DF18943891DA8A320FA2C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:to="loc_abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent_876A98134F8DF18943891DA8A320FA2C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCost1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_7A47082E0D429349B5751DA8A320D27F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_7A47082E0D429349B5751DA8A320D27F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_6845F8883F437392D5F81DA8A320BA11" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:to="loc_us-gaap_RestructuringCharges_6845F8883F437392D5F81DA8A320BA11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_8F20ABDD5D18672FF9A01DB3F59309EB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:to="loc_us-gaap_PaymentsForRestructuring_8F20ABDD5D18672FF9A01DB3F59309EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_51047828FFBA98A84C3C1DA8A320F8B2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_578697DD6DEEA97B01F71DAB96811BD2" xlink:to="loc_us-gaap_RestructuringReserve_51047828FFBA98A84C3C1DA8A320F8B2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SiteConsolidationNotes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_9408834672736FA8CE411DA8A160669F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_5AFB62E7A8D5E43DBB981DA8A163E895" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_9408834672736FA8CE411DA8A160669F" xlink:to="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_5AFB62E7A8D5E43DBB981DA8A163E895" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SiteConsolidationTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_4BA79C2195B397DD2BB91DA8A1B21C9D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_7883619FF584744421BC1DA8A1B3D3C7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_4BA79C2195B397DD2BB91DA8A1B21C9D" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_7883619FF584744421BC1DA8A1B3D3C7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SubsequentEvents" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaap_SubsequentEventsAbstract_69B0DFFE10FD55E9BA54551A16B51824" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventsTextBlock" xlink:label="loc_us-gaap_SubsequentEventsTextBlock_337F65764D325AE89D30C2A8DC804397" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_69B0DFFE10FD55E9BA54551A16B51824" xlink:to="loc_us-gaap_SubsequentEventsTextBlock_337F65764D325AE89D30C2A8DC804397" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://arbutusbio.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventsAbstract" xlink:label="loc_us-gaap_SubsequentEventsAbstract_00253157239AB7672DCF1DA8E120BDE3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventTable" xlink:label="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventsAbstract_00253157239AB7672DCF1DA8E120BDE3" xlink:to="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_B931B9225DB0DC7363681DDFC9C96D4A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:to="loc_dei_LegalEntityAxis_B931B9225DB0DC7363681DDFC9C96D4A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_BF1504A4604B7A3D1B871DDFC9CB9399" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_B931B9225DB0DC7363681DDFC9C96D4A" xlink:to="loc_dei_EntityDomain_BF1504A4604B7A3D1B871DDFC9CB9399" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_RoivantSciencesLtdMember" xlink:label="loc_abus_RoivantSciencesLtdMember_1256329EB8EC8D10A5591DDFF5A53E56" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_BF1504A4604B7A3D1B871DDFC9CB9399" xlink:to="loc_abus_RoivantSciencesLtdMember_1256329EB8EC8D10A5591DDFF5A53E56" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_DEBA09436E4EAAE040111DCD24C3876D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_DEBA09436E4EAAE040111DCD24C3876D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_F3C14A2AD85B3248BF071DCD24C78656" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_DEBA09436E4EAAE040111DCD24C3876D" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_F3C14A2AD85B3248BF071DCD24C78656" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_6D89EC701094F94967B71DCDA1BE7988" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_F3C14A2AD85B3248BF071DCD24C78656" xlink:to="loc_abus_GenevantSciencesCorporationMember_6D89EC701094F94967B71DCDA1BE7988" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_1A29DBA1F5483CE9CA651DA8E121336E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_1A29DBA1F5483CE9CA651DA8E121336E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_AC08AA92DAFAA0B6B5221DA8E1217DCF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_1A29DBA1F5483CE9CA651DA8E121336E" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_AC08AA92DAFAA0B6B5221DA8E1217DCF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_0686B7CB2B3BD6449B551DA8E121A22D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_AC08AA92DAFAA0B6B5221DA8E1217DCF" xlink:to="loc_us-gaap_SubsequentEventMember_0686B7CB2B3BD6449B551DA8E121A22D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_SubsequentEventLineItems" xlink:label="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTable_153B20E48B96E62707511DA8E120BB85" xlink:to="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EquityMethodInvestmentCapitalContribution" xlink:label="loc_abus_EquityMethodInvestmentCapitalContribution_31C20385686FF8DEB6CC1DDA3ADC3B47" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:to="loc_abus_EquityMethodInvestmentCapitalContribution_31C20385686FF8DEB6CC1DDA3ADC3B47" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_B9D33886833FDF6D82511DA8E121324F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_B9D33886833FDF6D82511DA8E121324F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2016/elts/us-gaap-2016-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_9D3BF0BDB8E18B7833311DDBC97BF218" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_9D3BF0BDB8E18B7833311DDBC97BF218" xlink:type="arc" />
    <link:loc xlink:href="abus-20180331.xsd#abus_EquityMethodInvestmentCommittedContribution" xlink:label="loc_abus_EquityMethodInvestmentCommittedContribution_3A373D4B3F3053167B8D1DDE3C9F7215" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventLineItems_C4ACF6743C29E881E5CB1DA8E121261B" xlink:to="loc_abus_EquityMethodInvestmentCommittedContribution_3A373D4B3F3053167B8D1DDE3C9F7215" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>





