

<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilities" xlink:href="abus-20181231.xsd#AccountsPayableAndAccruedLiabilities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilitiesDetails" xlink:href="abus-20181231.xsd#AccountsPayableAndAccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilitiesTables" xlink:href="abus-20181231.xsd#AccountsPayableAndAccruedLiabilitiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreements" xlink:href="abus-20181231.xsd#CollaborationsContractsAndLicensingAgreements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsDeferredCollaborationsAndContractsRevenueDetails" xlink:href="abus-20181231.xsd#CollaborationsContractsAndLicensingAgreementsDeferredCollaborationsAndContractsRevenueDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:href="abus-20181231.xsd#CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:href="abus-20181231.xsd#CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsTables" xlink:href="abus-20181231.xsd#CollaborationsContractsAndLicensingAgreementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRisk" xlink:href="abus-20181231.xsd#ConcentrationsOfBusinessRisk" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskForeignCurrencyExposureDetails" xlink:href="abus-20181231.xsd#ConcentrationsOfBusinessRiskForeignCurrencyExposureDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskNarrativeDetails" xlink:href="abus-20181231.xsd#ConcentrationsOfBusinessRiskNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskNetLiquidityDetails" xlink:href="abus-20181231.xsd#ConcentrationsOfBusinessRiskNetLiquidityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskTables" xlink:href="abus-20181231.xsd#ConcentrationsOfBusinessRiskTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedBalanceSheets" xlink:href="abus-20181231.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="abus-20181231.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedStatementOfStockholdersEquity" xlink:href="abus-20181231.xsd#ConsolidatedStatementOfStockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedStatementOfStockholdersEquityParenthetical" xlink:href="abus-20181231.xsd#ConsolidatedStatementOfStockholdersEquityParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedStatementsOfCashFlows" xlink:href="abus-20181231.xsd#ConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:href="abus-20181231.xsd#ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ContingenciesAndCommitments" xlink:href="abus-20181231.xsd#ContingenciesAndCommitments" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsMinimumRentAndEstimatedOperatingCostCommitmentNetOfLeaseInducementsDetails" xlink:href="abus-20181231.xsd#ContingenciesAndCommitmentsMinimumRentAndEstimatedOperatingCostCommitmentNetOfLeaseInducementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsNarrativeDetails" xlink:href="abus-20181231.xsd#ContingenciesAndCommitmentsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsTables" xlink:href="abus-20181231.xsd#ContingenciesAndCommitmentsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/DocumentAndEntityInformation" xlink:href="abus-20181231.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestment" xlink:href="abus-20181231.xsd#EquityMethodInvestment" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestmentBalanceSheetOfEquityMethodInvestmentDetails" xlink:href="abus-20181231.xsd#EquityMethodInvestmentBalanceSheetOfEquityMethodInvestmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestmentNarrativeDetails" xlink:href="abus-20181231.xsd#EquityMethodInvestmentNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestmentResultsOfOperationsOfEquityMethodInvestmentDetails" xlink:href="abus-20181231.xsd#EquityMethodInvestmentResultsOfOperationsOfEquityMethodInvestmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestmentScheduleOfEquityInvestmentBalanceDetails" xlink:href="abus-20181231.xsd#EquityMethodInvestmentScheduleOfEquityInvestmentBalanceDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/EquityMethodInvestmentTables" xlink:href="abus-20181231.xsd#EquityMethodInvestmentTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurements" xlink:href="abus-20181231.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="abus-20181231.xsd#FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfContingentConsiderationDetails" xlink:href="abus-20181231.xsd#FairValueMeasurementsChangesInFairValueOfContingentConsiderationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfLiabilitiesClassifiedAsStockOptionDetails" xlink:href="abus-20181231.xsd#FairValueMeasurementsChangesInFairValueOfLiabilitiesClassifiedAsStockOptionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfWarrantsDetails" xlink:href="abus-20181231.xsd#FairValueMeasurementsChangesInFairValueOfWarrantsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsNarrativeDetails" xlink:href="abus-20181231.xsd#FairValueMeasurementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/FairValueMeasurementsTables" xlink:href="abus-20181231.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IncomeTaxes" xlink:href="abus-20181231.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:href="abus-20181231.xsd#IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IncomeTaxesIncomeTaxReconciliationDetails" xlink:href="abus-20181231.xsd#IncomeTaxesIncomeTaxReconciliationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IncomeTaxesNarrativeDetails" xlink:href="abus-20181231.xsd#IncomeTaxesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IncomeTaxesTables" xlink:href="abus-20181231.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwill" xlink:href="abus-20181231.xsd#IntangibleAssetsAndGoodwill" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillNarrativeDetails" xlink:href="abus-20181231.xsd#IntangibleAssetsAndGoodwillNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:href="abus-20181231.xsd#IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillTables" xlink:href="abus-20181231.xsd#IntangibleAssetsAndGoodwillTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/InterimFinancialDataUnaudited" xlink:href="abus-20181231.xsd#InterimFinancialDataUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/InterimFinancialDataUnauditedDetails" xlink:href="abus-20181231.xsd#InterimFinancialDataUnauditedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/InterimFinancialDataUnauditedTables" xlink:href="abus-20181231.xsd#InterimFinancialDataUnauditedTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/LoanPayable" xlink:href="abus-20181231.xsd#LoanPayable" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/LoanPayableDetails" xlink:href="abus-20181231.xsd#LoanPayableDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/NatureOfBusinessAndFutureOperations" xlink:href="abus-20181231.xsd#NatureOfBusinessAndFutureOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/PropertyAndEquipment" xlink:href="abus-20181231.xsd#PropertyAndEquipment" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/PropertyAndEquipmentDetails" xlink:href="abus-20181231.xsd#PropertyAndEquipmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/PropertyAndEquipmentNarrativeDetails" xlink:href="abus-20181231.xsd#PropertyAndEquipmentNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/PropertyAndEquipmentTables" xlink:href="abus-20181231.xsd#PropertyAndEquipmentTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/RefundableInvestmentTaxCredits" xlink:href="abus-20181231.xsd#RefundableInvestmentTaxCredits" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/RefundableInvestmentTaxCreditsDetails" xlink:href="abus-20181231.xsd#RefundableInvestmentTaxCreditsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/RelatedPartyTransactions" xlink:href="abus-20181231.xsd#RelatedPartyTransactions" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/RelatedPartyTransactionsDetails" xlink:href="abus-20181231.xsd#RelatedPartyTransactionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ShareholdersEquity" xlink:href="abus-20181231.xsd#ShareholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/ShareholdersEquityDetails" xlink:href="abus-20181231.xsd#ShareholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPolicies" xlink:href="abus-20181231.xsd#SignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesComputationOfBasicAndDilutedNetIncomeLossPerCommonShareDetails" xlink:href="abus-20181231.xsd#SignificantAccountingPoliciesComputationOfBasicAndDilutedNetIncomeLossPerCommonShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesEstimatedUsefulLivesOfPropertyAndEquipmentDetails" xlink:href="abus-20181231.xsd#SignificantAccountingPoliciesEstimatedUsefulLivesOfPropertyAndEquipmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesNarrativeDetails" xlink:href="abus-20181231.xsd#SignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesPolicies" xlink:href="abus-20181231.xsd#SignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesTables" xlink:href="abus-20181231.xsd#SignificantAccountingPoliciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SiteConsolidation" xlink:href="abus-20181231.xsd#SiteConsolidation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SiteConsolidationDetails" xlink:href="abus-20181231.xsd#SiteConsolidationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/SiteConsolidationTables" xlink:href="abus-20181231.xsd#SiteConsolidationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensation" xlink:href="abus-20181231.xsd#StockBasedCompensation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationLiabilityClassifiedOptionsOutstandingDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationLiabilityClassifiedOptionsOutstandingDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationNarrativeDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationNonVestedStockOptionActivityDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationNonVestedStockOptionActivityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationNonVestedStockOptionActivityOncoreOptionPlanDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationNonVestedStockOptionActivityOncoreOptionPlanDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationOutstandingOptionsUnderOncoreOptionPlanDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationOutstandingOptionsUnderOncoreOptionPlanDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationOutstandingOptionsUnderProtivaOptionPlanDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationOutstandingOptionsUnderProtivaOptionPlanDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationStockBasedCompensationExpenseDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationStockBasedCompensationExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationStockOptionActivityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionActivityForLiabilityClassifiedOptionsDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationStockOptionActivityForLiabilityClassifiedOptionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionsOutstandingDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationStockOptionsOutstandingDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationTables" xlink:href="abus-20181231.xsd#StockBasedCompensationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationValuationAssumptionsForLiabilityClassifiedOptionsDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationValuationAssumptionsForLiabilityClassifiedOptionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.tekmirapharm.com/role/StockBasedCompensationValuationAssumptionsForStockOptionsDetails" xlink:href="abus-20181231.xsd#StockBasedCompensationValuationAssumptionsForStockOptionsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodEndLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodEndLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedPeriodStartLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedPeriodStartLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel" xlink:type="simple" />
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel" xlink:type="simple" />
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilities" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_463C7992C0D60C6357DCF28D4C1ED86B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SupplementalBalanceSheetDisclosuresTextBlock" xlink:label="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_FF95E8CC1A3328D28129F28D4C1ED3A5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_463C7992C0D60C6357DCF28D4C1ED86B" xlink:to="loc_us-gaap_SupplementalBalanceSheetDisclosuresTextBlock_FF95E8CC1A3328D28129F28D4C1ED3A5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableTradeCurrent" xlink:label="loc_us-gaap_AccountsPayableTradeCurrent_37DB6258E35C8C6C58842CDD360EE1F6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_us-gaap_AccountsPayableTradeCurrent_37DB6258E35C8C6C58842CDD360EE1F6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AccruedPayrollCurrent" xlink:label="loc_abus_AccruedPayrollCurrent_97D359B776000A9A1AB42CDD360FFABB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_abus_AccruedPayrollCurrent_97D359B776000A9A1AB42CDD360FFABB" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AccruedResearchandDevelopmentCurrent" xlink:label="loc_abus_AccruedResearchandDevelopmentCurrent_BE1C5E05D4803CDA8F8C2CDD360EC415" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_abus_AccruedResearchandDevelopmentCurrent_BE1C5E05D4803CDA8F8C2CDD360EC415" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccruedProfessionalFeesCurrent" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_271BC3BE7A682E0803E52CDD360EA8F2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_271BC3BE7A682E0803E52CDD360EA8F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseIncentivePayableCurrent" xlink:label="loc_us-gaap_LeaseIncentivePayableCurrent_3CFDB1979746CBE525E22CDD360E5B17" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_us-gaap_LeaseIncentivePayableCurrent_3CFDB1979746CBE525E22CDD360E5B17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_A1607A5E5A0E0E1438992CDD360F23AC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_A1607A5E5A0E0E1438992CDD360F23AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_6978B9C823B47E635A112CDD360F47FC" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_659BFE193146177E52812CDD360D95DF" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_6978B9C823B47E635A112CDD360F47FC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/AccountsPayableAndAccruedLiabilitiesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PayablesAndAccrualsAbstract" xlink:label="loc_us-gaap_PayablesAndAccrualsAbstract_9A204FB42D2F100CF017F28D542E8045" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_43217DA055C8DDA09FDCF28D542EF7CD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PayablesAndAccrualsAbstract_9A204FB42D2F100CF017F28D542E8045" xlink:to="loc_us-gaap_ScheduleOfAccountsPayableAndAccruedLiabilitiesTableTextBlock_43217DA055C8DDA09FDCF28D542EF7CD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_68CC6CEE78304FB06A27F285C994AF4F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CollaborativeArrangementDisclosureTextBlock" xlink:label="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_E71A763ABE582CC72689F285C995EA06" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_68CC6CEE78304FB06A27F285C994AF4F" xlink:to="loc_us-gaap_CollaborativeArrangementDisclosureTextBlock_E71A763ABE582CC72689F285C995EA06" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsDeferredCollaborationsAndContractsRevenueDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_2DE6515A8497A89BA9E73F0C9C658C69" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ContractwithCustomerLiabilityTable" xlink:label="loc_abus_ContractwithCustomerLiabilityTable_07132503458308527AEE3F0C9C65BC6A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_2DE6515A8497A89BA9E73F0C9C658C69" xlink:to="loc_abus_ContractwithCustomerLiabilityTable_07132503458308527AEE3F0C9C65BC6A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_7B92725A9D803CE124EC3F0C9C66A1C2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContractwithCustomerLiabilityTable_07132503458308527AEE3F0C9C65BC6A" xlink:to="loc_srt_CounterpartyNameAxis_7B92725A9D803CE124EC3F0C9C66A1C2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8AEBD9112DCFB2CF759D3F0C9C66A7F7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_7B92725A9D803CE124EC3F0C9C66A1C2" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8AEBD9112DCFB2CF759D3F0C9C66A7F7" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GritstoneMember" xlink:label="loc_abus_GritstoneMember_E21F9BA50CF4F8C504733F0C9C66D203" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8AEBD9112DCFB2CF759D3F0C9C66A7F7" xlink:to="loc_abus_GritstoneMember_E21F9BA50CF4F8C504733F0C9C66D203" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OtherMilestoneandRoyaltyPaymentsMember" xlink:label="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_2197B2C3533A32A0CAFD3F11167DFBDA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8AEBD9112DCFB2CF759D3F0C9C66A7F7" xlink:to="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_2197B2C3533A32A0CAFD3F11167DFBDA" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ContractwithCustomerLiabilityLineItems" xlink:label="loc_abus_ContractwithCustomerLiabilityLineItems_329FAC054AAC0451BDC23F0C9C67978C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContractwithCustomerLiabilityTable_07132503458308527AEE3F0C9C65BC6A" xlink:to="loc_abus_ContractwithCustomerLiabilityLineItems_329FAC054AAC0451BDC23F0C9C67978C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerLiability" xlink:label="loc_us-gaap_ContractWithCustomerLiability_3455828557D45C6857883F0C9C6786FE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContractwithCustomerLiabilityLineItems_329FAC054AAC0451BDC23F0C9C67978C" xlink:to="loc_us-gaap_ContractWithCustomerLiability_3455828557D45C6857883F0C9C6786FE" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_6A852340875BF85DFC16402213D947F1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable" xlink:label="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_6A852340875BF85DFC16402213D947F1" xlink:to="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_F7C3470D53AA03D14D23402213DA310E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_F7C3470D53AA03D14D23402213DA310E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_9365E8201DD68CFD3939402213DA85B9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_F7C3470D53AA03D14D23402213DA310E" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_9365E8201DD68CFD3939402213DA85B9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_A0BC2E83F522D242A0B1402213DA0EE5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_9365E8201DD68CFD3939402213DA85B9" xlink:to="loc_abus_GenevantSciencesCorporationMember_A0BC2E83F522D242A0B1402213DA0EE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_34B2FEC8507BB7816DA1402213DA1C97" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:to="loc_srt_ProductOrServiceAxis_34B2FEC8507BB7816DA1402213DA1C97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_050AC70F45FB829BC6A2402213DBBE66" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_34B2FEC8507BB7816DA1402213DA1C97" xlink:to="loc_srt_ProductsAndServicesDomain_050AC70F45FB829BC6A2402213DBBE66" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LicenseMember" xlink:label="loc_us-gaap_LicenseMember_74BEA3A05D60E2C0D47B402213DBF6A0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_050AC70F45FB829BC6A2402213DBBE66" xlink:to="loc_us-gaap_LicenseMember_74BEA3A05D60E2C0D47B402213DBF6A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_3750F377BB24D02D6155402213DB833D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_3750F377BB24D02D6155402213DB833D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_8E8C3FC40420D215D9A6402213DB6737" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis_3750F377BB24D02D6155402213DB833D" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_8E8C3FC40420D215D9A6402213DB6737" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_MarqiboCommercialSalesMember" xlink:label="loc_abus_MarqiboCommercialSalesMember_418B30C75218A993C2FA402213DC30F2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersTypeDomain_8E8C3FC40420D215D9A6402213DB6737" xlink:to="loc_abus_MarqiboCommercialSalesMember_418B30C75218A993C2FA402213DC30F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_A8EAC1556890218FECA7402213DC7514" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:to="loc_srt_CounterpartyNameAxis_A8EAC1556890218FECA7402213DC7514" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_A8EAC1556890218FECA7402213DC7514" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AlexionMember" xlink:label="loc_abus_AlexionMember_158020166DDA2E297557402213DCDB19" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_AlexionMember_158020166DDA2E297557402213DCDB19" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TalonTherapeuticsMember" xlink:label="loc_abus_TalonTherapeuticsMember_CB8E4B057A59E5E015CF402213DD7DD6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_TalonTherapeuticsMember_CB8E4B057A59E5E015CF402213DD7DD6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GritstoneMember" xlink:label="loc_abus_GritstoneMember_633638E37E36E6E49B15402213DD4BC0" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_GritstoneMember_633638E37E36E6E49B15402213DD4BC0" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GritstoneMilestoneMember" xlink:label="loc_abus_GritstoneMilestoneMember_3DAB2C887D77CB056347402213DD5805" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_GritstoneMilestoneMember_3DAB2C887D77CB056347402213DD5805" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AlnylamPharmaceuticalsIncMember" xlink:label="loc_abus_AlnylamPharmaceuticalsIncMember_79832BD2E9547D30F51040929FCEAA27" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_AlnylamPharmaceuticalsIncMember_79832BD2E9547D30F51040929FCEAA27" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AcuitasTherapeuticsInc.Member" xlink:label="loc_abus_AcuitasTherapeuticsInc.Member_66B5D86F8BB7B7F4851F40963A528CA7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_B1EB871EB3463F05E09F402213DC1278" xlink:to="loc_abus_AcuitasTherapeuticsInc.Member_66B5D86F8BB7B7F4851F40963A528CA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems" xlink:label="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfResearchAndDevelopmentArrangementContractToPerformForOthersTable_65DE228DD90E3692B8B4402213D9D25C" xlink:to="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_LicenseUpfrontPayment" xlink:label="loc_abus_LicenseUpfrontPayment_948E650FAA60F2AAB219402213DD5C39" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_abus_LicenseUpfrontPayment_948E650FAA60F2AAB219402213DD5C39" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentPercentageOfRevenueEntitled" xlink:label="loc_abus_EquityMethodInvestmentPercentageOfRevenueEntitled_1B1EBDF06BFDC3994A4A402213DE26E3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_abus_EquityMethodInvestmentPercentageOfRevenueEntitled_1B1EBDF06BFDC3994A4A402213DE26E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromCustomersForProgressPayments" xlink:label="loc_us-gaap_ProceedsFromCustomersForProgressPayments_93BA4E0851D27DFC962D402213DE05B7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_us-gaap_ProceedsFromCustomersForProgressPayments_93BA4E0851D27DFC962D402213DE05B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_FA0E016E49130A93779E402213DE32D2" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_us-gaap_Revenues_FA0E016E49130A93779E402213DE32D2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TermofCollaborationAgreement" xlink:label="loc_abus_TermofCollaborationAgreement_E46AC8A0D3A0730C656B4094F525BC02" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_abus_TermofCollaborationAgreement_E46AC8A0D3A0730C656B4094F525BC02" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NumberOfChemotherapyProductsWithWorldwideLicenses" xlink:label="loc_abus_NumberOfChemotherapyProductsWithWorldwideLicenses_015AB6A9A93D3D4DC089402213DED0A6" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_abus_NumberOfChemotherapyProductsWithWorldwideLicenses_015AB6A9A93D3D4DC089402213DED0A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_5553C1FF7C2A9967A2D9402213DEF202" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_5553C1FF7C2A9967A2D9402213DEF202" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PotentialContractFundingAmount" xlink:label="loc_abus_PotentialContractFundingAmount_591FE84EC298E534FC95402213DE31EA" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersLineItems_B9EAB0D17C9DD7F5B7F5402213DD876A" xlink:to="loc_abus_PotentialContractFundingAmount_591FE84EC298E534FC95402213DE31EA" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsRevenueRecognizedUnderCollaborationsContractsAndLicensingAgreementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_94D407770BF21B8F1B4B3F0A666492FC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_A1A9009943BEEEB295563F0A66650E1E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_94D407770BF21B8F1B4B3F0A666492FC" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_A1A9009943BEEEB295563F0A66650E1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_BB31209BB9B1AD3E2ACF3F0A6668BCA5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_A1A9009943BEEEB295563F0A66650E1E" xlink:to="loc_srt_CounterpartyNameAxis_BB31209BB9B1AD3E2ACF3F0A6668BCA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C291F4CA8B255A9C79123F0A6668D262" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_BB31209BB9B1AD3E2ACF3F0A6668BCA5" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C291F4CA8B255A9C79123F0A6668D262" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AlexionMember" xlink:label="loc_abus_AlexionMember_0AE816F833982FD4B6103F0A6668DDB5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C291F4CA8B255A9C79123F0A6668D262" xlink:to="loc_abus_AlexionMember_0AE816F833982FD4B6103F0A6668DDB5" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GritstoneMember" xlink:label="loc_abus_GritstoneMember_31B09F48F942761B6D553F0A66697201" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C291F4CA8B255A9C79123F0A6668D262" xlink:to="loc_abus_GritstoneMember_31B09F48F942761B6D553F0A66697201" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OtherMilestoneandRoyaltyPaymentsMember" xlink:label="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_F13A618889F29AE5D7A23F0A666F1E5E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C291F4CA8B255A9C79123F0A6668D262" xlink:to="loc_abus_OtherMilestoneandRoyaltyPaymentsMember_F13A618889F29AE5D7A23F0A666F1E5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_4D574A7B87373070AA883F0A6665E53C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_A1A9009943BEEEB295563F0A66650E1E" xlink:to="loc_srt_ProductOrServiceAxis_4D574A7B87373070AA883F0A6665E53C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_17C1CA8DC940D70E342F3F0A66664B29" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_4D574A7B87373070AA883F0A6665E53C" xlink:to="loc_srt_ProductsAndServicesDomain_17C1CA8DC940D70E342F3F0A66664B29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LicenseMember" xlink:label="loc_us-gaap_LicenseMember_E5F1191DE7DF016A9C933F0A6667729F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_17C1CA8DC940D70E342F3F0A66664B29" xlink:to="loc_us-gaap_LicenseMember_E5F1191DE7DF016A9C933F0A6667729F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems" xlink:label="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_83E374FCA648409173443F0A666F9A3F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTable_A1A9009943BEEEB295563F0A66650E1E" xlink:to="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_83E374FCA648409173443F0A666F9A3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_40C3447649A4A1C251AD3F0A66708FFF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems_83E374FCA648409173443F0A666F9A3F" xlink:to="loc_us-gaap_Revenues_40C3447649A4A1C251AD3F0A66708FFF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/CollaborationsContractsAndLicensingAgreementsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerAbstract" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerAbstract_24F8CDC59E8B13D237BA3F2841B51C09" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock_A9562B6C6C242FB69CED3F0A1A72F4EA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_24F8CDC59E8B13D237BA3F2841B51C09" xlink:to="loc_us-gaap_ScheduleOfCollaborativeArrangementsAndNoncollaborativeArrangementTransactionsTableTextBlock_A9562B6C6C242FB69CED3F0A1A72F4EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_8A8152C2DE4D69A6266C3F0A1A74DD64" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenueFromContractWithCustomerAbstract_24F8CDC59E8B13D237BA3F2841B51C09" xlink:to="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_8A8152C2DE4D69A6266C3F0A1A74DD64" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRisk" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_4826CF69720642939A2CF28A3BADA851" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskDisclosureTextBlock" xlink:label="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_105CED0E64D7B9C92FF5F28A3BAD3FB3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_4826CF69720642939A2CF28A3BADA851" xlink:to="loc_us-gaap_ConcentrationRiskDisclosureTextBlock_105CED0E64D7B9C92FF5F28A3BAD3FB3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskForeignCurrencyExposureDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_AE36787C2BAD3D666C2B4022139099BF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIntercompanyForeignCurrencyBalanceTable" xlink:label="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalanceTable_512164344958FDE1F0C44022139070B7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_AE36787C2BAD3D666C2B4022139099BF" xlink:to="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalanceTable_512164344958FDE1F0C44022139070B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_C83623E7FF26052FCA27402213905ACC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalanceTable_512164344958FDE1F0C44022139070B7" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_C83623E7FF26052FCA27402213905ACC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_0C7E1001978773AE0741402213900D7C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_C83623E7FF26052FCA27402213905ACC" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_0C7E1001978773AE0741402213900D7C" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ForeignCurrencyExposureMember" xlink:label="loc_abus_ForeignCurrencyExposureMember_D095AFE9BC4575F19F2040221390A7AE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_0C7E1001978773AE0741402213900D7C" xlink:to="loc_abus_ForeignCurrencyExposureMember_D095AFE9BC4575F19F2040221390A7AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IntercompanyForeignCurrencyBalanceLineItems" xlink:label="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalanceTable_512164344958FDE1F0C44022139070B7" xlink:to="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_50DF84808160B39C737340221390DB11" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_50DF84808160B39C737340221390DB11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNet" xlink:label="loc_us-gaap_AccountsReceivableNet_7CD4B3022767D96454C840221390CD35" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:to="loc_us-gaap_AccountsReceivableNet_7CD4B3022767D96454C840221390CD35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnbilledReceivablesCurrent" xlink:label="loc_us-gaap_UnbilledReceivablesCurrent_2A8615E67D3CC89BEAB0402213903902" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:to="loc_us-gaap_UnbilledReceivablesCurrent_2A8615E67D3CC89BEAB0402213903902" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_76ABD95E1C9DBCC24B14402213904BE9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_76ABD95E1C9DBCC24B14402213904BE9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ExposuretoCanadianDollar" xlink:label="loc_abus_ExposuretoCanadianDollar_27312A65BE1AD354D1ED402213905872" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IntercompanyForeignCurrencyBalanceLineItems_FDFBC4AA46F43EBEC8E5402213901249" xlink:to="loc_abus_ExposuretoCanadianDollar_27312A65BE1AD354D1ED402213905872" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_AD4A86BCF32CA8C2EC1AAD3F997041C8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNet" xlink:label="loc_us-gaap_AccountsReceivableNet_7FE878DC5433E231A837AD3F997074E7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_AD4A86BCF32CA8C2EC1AAD3F997041C8" xlink:to="loc_us-gaap_AccountsReceivableNet_7FE878DC5433E231A837AD3F997074E7" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ThresholdPeriodToPayAccountsPayables" xlink:label="loc_abus_ThresholdPeriodToPayAccountsPayables_7801080CD6B3D54B5207AD3F997089A7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_AD4A86BCF32CA8C2EC1AAD3F997041C8" xlink:to="loc_abus_ThresholdPeriodToPayAccountsPayables_7801080CD6B3D54B5207AD3F997089A7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskNetLiquidityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_F7EECAAD969DD4CE7684402213909113" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_CA9116D8B38B396B948B40221390621E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_F7EECAAD969DD4CE7684402213909113" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_CA9116D8B38B396B948B40221390621E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_634D5CF91528902896AF402213900BF9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_F7EECAAD969DD4CE7684402213909113" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrentAndNoncurrent_634D5CF91528902896AF402213900BF9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NetLiquidity" xlink:label="loc_abus_NetLiquidity_89C7A5EE707DF1089D6240221390E72F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_F7EECAAD969DD4CE7684402213909113" xlink:to="loc_abus_NetLiquidity_89C7A5EE707DF1089D6240221390E72F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConcentrationsOfBusinessRiskTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RisksAndUncertaintiesAbstract" xlink:label="loc_us-gaap_RisksAndUncertaintiesAbstract_B0D8BBCD6A198FEACA58402213A08491" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NetLiquidityDisclosureTableTextBlock" xlink:label="loc_abus_NetLiquidityDisclosureTableTextBlock_7568C136242804175C7A402213A06E84" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_B0D8BBCD6A198FEACA58402213A08491" xlink:to="loc_abus_NetLiquidityDisclosureTableTextBlock_7568C136242804175C7A402213A06E84" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIntercompanyForeignCurrencyBalancesTextBlock" xlink:label="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalancesTextBlock_DF4CB7C1EB57C9C027F2402213A0FC0D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RisksAndUncertaintiesAbstract_B0D8BBCD6A198FEACA58402213A08491" xlink:to="loc_us-gaap_ScheduleOfIntercompanyForeignCurrencyBalancesTextBlock_DF4CB7C1EB57C9C027F2402213A0FC0D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_E6D7C0DD6A578A2B8B8C59102F3A6B69" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsAbstract" xlink:label="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_E6D7C0DD6A578A2B8B8C59102F3A6B69" xlink:to="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrentAbstract" xlink:label="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_BBEFF3F015DD0B2FD0CD59102F3DBB08" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_BBEFF3F015DD0B2FD0CD59102F3DBB08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShortTermInvestments" xlink:label="loc_us-gaap_ShortTermInvestments_5040DA63E55F5BAADBF659102F3E60FD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_ShortTermInvestments_5040DA63E55F5BAADBF659102F3E60FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_80ABD20251EDF017688659102F3E4A6D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_80ABD20251EDF017688659102F3E4A6D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UnbilledReceivablesCurrent" xlink:label="loc_us-gaap_UnbilledReceivablesCurrent_1CF392B5A8D62E4A311059102F3ED0E8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_UnbilledReceivablesCurrent_1CF392B5A8D62E4A311059102F3ED0E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxesReceivable" xlink:label="loc_us-gaap_IncomeTaxesReceivable_8568DB5EA6FE3E13492159102F3E7C94" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_IncomeTaxesReceivable_8568DB5EA6FE3E13492159102F3E7C94" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_304834411C11E6AFB00F59102F3E2F43" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_304834411C11E6AFB00F59102F3E2F43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsCurrent" xlink:label="loc_us-gaap_AssetsCurrent_018526F50D9C108F3E7059102F3E763E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_31F38E0E92A8786FDDBC59102F3DBDB4" xlink:to="loc_us-gaap_AssetsCurrent_018526F50D9C108F3E7059102F3E763E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedInvestmentsNoncurrent" xlink:label="loc_us-gaap_RestrictedInvestmentsNoncurrent_488458D931E3006FDB8E59102F3F6B92" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_RestrictedInvestmentsNoncurrent_488458D931E3006FDB8E59102F3F6B92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_us-gaap_EquityMethodInvestments_6F0E3B71ACEB3101C72359102F3F643B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_EquityMethodInvestments_6F0E3B71ACEB3101C72359102F3F643B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_548494B83D176B8A1CC059102F3FBCB1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_548494B83D176B8A1CC059102F3FBCB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1384CD52F314F0413B4259102F44F1C9" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_1384CD52F314F0413B4259102F44F1C9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_65EBF40224AE8BD0EE5B59102F45EEEE" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_65EBF40224AE8BD0EE5B59102F45EEEE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_A34D5B806F8F4657F5A859102F4573A7" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_A34D5B806F8F4657F5A859102F4573A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_D5629046617FFFBDD3C459102F45129B" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_Goodwill_D5629046617FFFBDD3C459102F45129B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_8024096D517B185787B059102F45F6A0" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_EF7F89C0763140A969BE59102F3A29C1" xlink:to="loc_us-gaap_Assets_8024096D517B185787B059102F45F6A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_E6D7C0DD6A578A2B8B8C59102F3A6B69" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_8A9103A4C8C7AA7F903659102F47029F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesCurrent_8A9103A4C8C7AA7F903659102F47029F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_A315E2655991187F669A59102F47B597" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_A315E2655991187F669A59102F47B597" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringReserveCurrent" xlink:label="loc_us-gaap_RestructuringReserveCurrent_8F16EF094CC2A08ABBA059102F473404" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:to="loc_us-gaap_RestructuringReserveCurrent_8F16EF094CC2A08ABBA059102F473404" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstanding" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstanding_3FBC6AF2F0DB84BDDFA959102F47934C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstanding_3FBC6AF2F0DB84BDDFA959102F47934C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesCurrent" xlink:label="loc_us-gaap_LiabilitiesCurrent_E2C5E01641EA95C49CEC59102F48D318" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_5C14B4EE1BBC75DA366059102F466B0E" xlink:to="loc_us-gaap_LiabilitiesCurrent_E2C5E01641EA95C49CEC59102F48D318" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredRentCreditNoncurrent" xlink:label="loc_us-gaap_DeferredRentCreditNoncurrent_00D6A0A73BA2F9A50EFC59102F483E7B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_DeferredRentCreditNoncurrent_00D6A0A73BA2F9A50EFC59102F483E7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongTermLoansPayable" xlink:label="loc_us-gaap_LongTermLoansPayable_96BE665C4A177AADC60A59102F4895C1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_LongTermLoansPayable_96BE665C4A177AADC60A59102F4895C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_838B125C7976310238F659102F49329A" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_838B125C7976310238F659102F49329A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilitiesNet" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_3EF91AFCCED286A76DA459102F491BDB" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilitiesNet_3EF91AFCCED286A76DA459102F491BDB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_8C649407271E9E85CE2F59102F49E703" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_Liabilities_8C649407271E9E85CE2F59102F49E703" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_F0F700B7DD2AB4993B1759102F468FE5" xlink:to="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount" xlink:label="loc_us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount_01B760B62A060CF2F3C259102F4978F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_PreferredStockIncludingAdditionalPaidInCapitalNetOfDiscount_01B760B62A060CF2F3C259102F4978F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_EBCB9C56820F97F9F51C59102F4A5725" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_CommonStockValue_EBCB9C56820F97F9F51C59102F4A5725" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaap_AdditionalPaidInCapital_7E87C3C5F6310FDCAE7A59102F4A6C52" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_AdditionalPaidInCapital_7E87C3C5F6310FDCAE7A59102F4A6C52" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_B61366BEC43AC31836E259102F4A62B8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_B61366BEC43AC31836E259102F4A62B8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C7549C45CFE2CF7E963559102F4A141B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_C7549C45CFE2CF7E963559102F4A141B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_99F48FE3D29CC4C00D9959102F4B9C86" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_C9C6CCC2B19641099B9E59102F49F127" xlink:to="loc_us-gaap_StockholdersEquity_99F48FE3D29CC4C00D9959102F4B9C86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_7EC069AA4C15BEFCEB8259102F4BC585" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_E6D7C0DD6A578A2B8B8C59102F3A6B69" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_7EC069AA4C15BEFCEB8259102F4BC585" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockNoParValue" xlink:label="loc_us-gaap_PreferredStockNoParValue_DA6A093C1918E1A0856C16F446BCD0BD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_PreferredStockNoParValue_DA6A093C1918E1A0856C16F446BCD0BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_F59E062A671EA7DAF50D16F4468E4B6C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_F59E062A671EA7DAF50D16F4468E4B6C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="loc_us-gaap_PreferredStockSharesIssued_AB1F06EEF576CFFBA78D16F4468D7E40" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_PreferredStockSharesIssued_AB1F06EEF576CFFBA78D16F4468D7E40" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_95A3827C1CD270A03AFA16F4468DC382" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_95A3827C1CD270A03AFA16F4468DC382" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockNoParValue" xlink:label="loc_us-gaap_CommonStockNoParValue_465B78D2DEC5C302BE4416F4468EBBB5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_CommonStockNoParValue_465B78D2DEC5C302BE4416F4468EBBB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_2C5AB21B2965B04C9F0B16F4468E51CC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_CommonStockSharesIssued_2C5AB21B2965B04C9F0B16F4468E51CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_A4BB857D8589274845FE16F4468E1FA5" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_819CB24DFC0D1BC5977B16F4468A75B9" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_A4BB857D8589274845FE16F4468E1FA5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedStatementOfStockholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_970F002D2607CD59A6DE16F497A977C8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementTable" xlink:label="loc_us-gaap_StatementTable_2809C4D6F5F1329C77E316F497A9C6B7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_970F002D2607CD59A6DE16F497A977C8" xlink:to="loc_us-gaap_StatementTable_2809C4D6F5F1329C77E316F497A9C6B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_039C0ED2099F65545E0316F497A91D2B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_2809C4D6F5F1329C77E316F497A9C6B7" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_039C0ED2099F65545E0316F497A91D2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_039C0ED2099F65545E0316F497A91D2B" xlink:to="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="loc_us-gaap_PreferredStockMember_59B1A7ABD275995150ED16F497AA61E6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:to="loc_us-gaap_PreferredStockMember_59B1A7ABD275995150ED16F497AA61E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_5FE0C655748D8C79324216F497AAC4CE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:to="loc_us-gaap_CommonStockMember_5FE0C655748D8C79324216F497AAC4CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_C95D2B5370C133A1A0A016F497AABED7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_C95D2B5370C133A1A0A016F497AABED7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_71E1A74D82ED2566B9DB16F497AAB011" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:to="loc_us-gaap_RetainedEarningsMember_71E1A74D82ED2566B9DB16F497AAB011" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_FD5A112C368B4D7C3A1316F497ABF7BA" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A39A549DE41C9852A8DC16F497A9082C" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_FD5A112C368B4D7C3A1316F497ABF7BA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementLineItems" xlink:label="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_2809C4D6F5F1329C77E316F497A9C6B7" xlink:to="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_B10EB24A72CC7625319816F497ABD167" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_SharesIssued_B10EB24A72CC7625319816F497ABD167" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_51ADD4216023E0A728BD16F497ABCA61" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockholdersEquity_51ADD4216023E0A728BD16F497ABCA61" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_9962C2783D2240269FB016F497ADB878" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_9962C2783D2240269FB016F497ADB878" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_76D3554E208E3B37544616F497AD3609" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_76D3554E208E3B37544616F497AD3609" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockAccretionOfRedemptionDiscount" xlink:label="loc_us-gaap_PreferredStockAccretionOfRedemptionDiscount_654B9CDA52B37989A51B16F497ACC287" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_PreferredStockAccretionOfRedemptionDiscount_654B9CDA52B37989A51B16F497ACC287" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_3D945F8172BD81F153BD16F497AC82C2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_3D945F8172BD81F153BD16F497AC82C2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards" xlink:label="loc_abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards_BA87E8C43DCE2AEF7F1616F497AC06CE" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_abus_AdjustmentstoAdditionalPaidinCapitalCertainFairValueAdjustmentstoLiabilityStockOptionAwards_BA87E8C43DCE2AEF7F1616F497AC06CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_9D6E2BF4CD56A0500B2E16F497AC0736" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_9D6E2BF4CD56A0500B2E16F497AC0736" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_BC1153401F279BDD5CBA16F497AD3382" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_BC1153401F279BDD5CBA16F497AD3382" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesOther" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesOther_86525D94B2887AC3018816F497ADA168" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesOther_86525D94B2887AC3018816F497ADA168" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueOther" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueOther_31CCC24A5FA22C597B0A16F497AD4F58" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueOther_31CCC24A5FA22C597B0A16F497AD4F58" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_D814FAC0AE93EB9381C617173896C990" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_D814FAC0AE93EB9381C617173896C990" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_530DD504B0E93639113216F497AE37C3" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_NetIncomeLoss_530DD504B0E93639113216F497AE37C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharesIssued" xlink:label="loc_us-gaap_SharesIssued_FACA3A9239DCB3B9FE0816F497AE1ED5" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_SharesIssued_FACA3A9239DCB3B9FE0816F497AE1ED5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_CA51FE787CFE7179A01916F497AEB93D" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_C8FD5635909EE4F9771A16F497AB0975" xlink:to="loc_us-gaap_StockholdersEquity_CA51FE787CFE7179A01916F497AEB93D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedStatementOfStockholdersEquityParenthetical" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_73B20376FDAA72A2953A16F497A37F77" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_E87598350D289EA9FCA616F497A3A7BF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_73B20376FDAA72A2953A16F497A37F77" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalStockIssuedIssuanceCosts_E87598350D289EA9FCA616F497A3A7BF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedStatementsOfCashFlows" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_A39A1B0E256CDCFAD674402216811B8F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:to="loc_us-gaap_NetIncomeLoss_A39A1B0E256CDCFAD674402216811B8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:to="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_8350C56F9303DE040C66402216817490" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_8350C56F9303DE040C66402216817490" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_AB6A24C9FC906890012640221682B470" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_Depreciation_AB6A24C9FC906890012640221682B470" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:label="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_7C4D0F3371949ABB9EAB40221682623F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_7C4D0F3371949ABB9EAB40221682623F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_0DD212902F4EBC69F34140221682BFED" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_ShareBasedCompensation_0DD212902F4EBC69F34140221682BFED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossUnrealized" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_9B5DAC26AC09F27AC74E4022168242BC" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_9B5DAC26AC09F27AC74E4022168242BC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueOptionChangesInFairValueGainLoss1" xlink:label="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_21BB5C2E897742CE85C640221683DDB3" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_21BB5C2E897742CE85C640221683DDB3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_EACB28B66655C77F85B940221683311E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_EACB28B66655C77F85B940221683311E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_8BB129DB46D1EF777F5940221683BD37" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_8BB129DB46D1EF777F5940221683BD37" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCosts" xlink:label="loc_us-gaap_RestructuringCosts_E4EC71F827889CC6FA2A40221683FBB4" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_RestructuringCosts_E4EC71F827889CC6FA2A40221683FBB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GainLossOnInvestments" xlink:label="loc_us-gaap_GainLossOnInvestments_16250636A91FE8AD80B140221683A857" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_GainLossOnInvestments_16250636A91FE8AD80B140221683A857" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GainLossOnSaleOfEquityInvestments" xlink:label="loc_us-gaap_GainLossOnSaleOfEquityInvestments_8F3FD70C14D33969F0D140221683E6CD" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsNoncashItemsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_713FFC78CD2640B392E440221681912D" xlink:to="loc_us-gaap_GainLossOnSaleOfEquityInvestments_8F3FD70C14D33969F0D140221683E6CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_2867222ABE778E26890940221684716A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_2867222ABE778E26890940221684716A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerAsset" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerAsset_21C4038847D27EEF6845402216841E24" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerAsset_21C4038847D27EEF6845402216841E24" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInIncomeTaxesReceivable" xlink:label="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_6E45A0E04DE37F27240C402216844A46" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInIncomeTaxesReceivable_6E45A0E04DE37F27240C402216844A46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_E4DBAF12E1723EE524474022168484C1" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_E4DBAF12E1723EE524474022168484C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_AA1FA7BAFA595C90A6DE40221685BDE4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_AA1FA7BAFA595C90A6DE40221685BDE4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_4376EAC053E8A34238DC40221685E7AC" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_4376EAC053E8A34238DC40221685E7AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredCharges" xlink:label="loc_us-gaap_IncreaseDecreaseInDeferredCharges_F81015D07438E723AA5940221685B9B7" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInDeferredCharges_F81015D07438E723AA5940221685B9B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncreaseDecreaseInRestructuringReserve" xlink:label="loc_us-gaap_IncreaseDecreaseInRestructuringReserve_D9DE43E92C68112BABCC402216853B4A" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_310662504838E875C51D402216847DD3" xlink:to="loc_us-gaap_IncreaseDecreaseInRestructuringReserve_D9DE43E92C68112BABCC402216853B4A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_DB8FF229BDE536A76021402216854FB6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_EA136B9197DBA5CBE2B440221681F0E3" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_DB8FF229BDE536A76021402216854FB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsForProceedsFromInvestments" xlink:label="loc_us-gaap_PaymentsForProceedsFromInvestments_97B664C9BB4B2981C4DA40221686722E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:to="loc_us-gaap_PaymentsForProceedsFromInvestments_97B664C9BB4B2981C4DA40221686722E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_C35BA3C7E08435EE84E840221686FABE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_C35BA3C7E08435EE84E840221686FABE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_50F053098E4FAB2887A740221686BE16" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_50F053098E4FAB2887A740221686BE16" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_50DE5E8E57127BDE2E07402216862293" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_BDE686FC152734E3906C40221686B27B" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_50DE5E8E57127BDE2E07402216862293" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RepaymentsOfNotesPayable" xlink:label="loc_us-gaap_RepaymentsOfNotesPayable_F55463FEEF8E047FBEC7402216871A31" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:to="loc_us-gaap_RepaymentsOfNotesPayable_F55463FEEF8E047FBEC7402216871A31" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_CFDF667F0C42C12172304022168CD963" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_CFDF667F0C42C12172304022168CD963" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="loc_us-gaap_ProceedsFromStockOptionsExercised_8246DA169EFA54399F8A4022168CAE8D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:to="loc_us-gaap_ProceedsFromStockOptionsExercised_8246DA169EFA54399F8A4022168CAE8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_E1F268D12B21E36147424022168D2E28" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_E1F268D12B21E36147424022168D2E28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_84DD3F8E8A51B2AB8AE54022168D71E2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_50B5C3F6FE6B6812EABA40221687A263" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_84DD3F8E8A51B2AB8AE54022168D71E2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_768FD2D26CD208B523894022168DD001" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashAndCashEquivalents_768FD2D26CD208B523894022168DD001" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_BECDFEA433A7D1738D844022168D0B13" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_BECDFEA433A7D1738D844022168D0B13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_39B397493A807A7800434022168D1195" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_39B397493A807A7800434022168D1195" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_3B06074E6AB0D8D498994022168DB873" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_3B06074E6AB0D8D498994022168DB873" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_9830941AF9D0304B85F94022168DFFFD" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_D2DCF278C08DD5F1C67D40221680E5CF" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_9830941AF9D0304B85F94022168DFFFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DividendsPreferredStockCash" xlink:label="loc_us-gaap_DividendsPreferredStockCash_82AE8E416FE6EC4E34474022168ED343" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_9830941AF9D0304B85F94022168DFFFD" xlink:to="loc_us-gaap_DividendsPreferredStockCash_82AE8E416FE6EC4E34474022168ED343" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContributionOfProperty" xlink:label="loc_us-gaap_ContributionOfProperty_4480B9B3FFAE69FFBFE54022168EFB60" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_9830941AF9D0304B85F94022168DFFFD" xlink:to="loc_us-gaap_ContributionOfProperty_4480B9B3FFAE69FFBFE54022168EFB60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIncomeTaxRefunds" xlink:label="loc_us-gaap_ProceedsFromIncomeTaxRefunds_2E0E78EDD29F42E9F89C4022168E8AA4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_9830941AF9D0304B85F94022168DFFFD" xlink:to="loc_us-gaap_ProceedsFromIncomeTaxRefunds_2E0E78EDD29F42E9F89C4022168E8AA4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ConsolidatedStatementsOfOperationsAndComprehensiveLoss" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenuesAbstract" xlink:label="loc_us-gaap_RevenuesAbstract_D392E17C17BD86C8B3D35854F389E46E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_RevenuesAbstract_D392E17C17BD86C8B3D35854F389E46E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_DE50239FB6A76AEAC6905854F389B78A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_D392E17C17BD86C8B3D35854F389E46E" xlink:to="loc_us-gaap_Revenues_DE50239FB6A76AEAC6905854F389B78A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostsAndExpensesAbstract" xlink:label="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_DE11B06FE43E4EA10C4D5854F3891FF9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_DE11B06FE43E4EA10C4D5854F3891FF9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_46757CECCAC0D3151A7F5854F3898F0A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_46757CECCAC0D3151A7F5854F3898F0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Depreciation" xlink:label="loc_us-gaap_Depreciation_F4B41ADD5B6BC5F04E575854F389B8DC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_Depreciation_F4B41ADD5B6BC5F04E575854F389B8DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_811240E91494C8E1BE115854F3895134" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_RestructuringCharges_811240E91494C8E1BE115854F3895134" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_51B68A293C36AC4E19D45854F389B154" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_51B68A293C36AC4E19D45854F389B154" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingExpenses" xlink:label="loc_us-gaap_OperatingExpenses_7C541724436BEF8A574A5854F389DDF8" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CostsAndExpensesAbstract_EC5882A7F298368B93565854F3894AB4" xlink:to="loc_us-gaap_OperatingExpenses_7C541724436BEF8A574A5854F389DDF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_4203B90797CF244F78375854F38921FB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_OperatingIncomeLoss_4203B90797CF244F78375854F38921FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NonoperatingIncomeExpenseAbstract" xlink:label="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentIncomeInterest" xlink:label="loc_us-gaap_InvestmentIncomeInterest_3C11A1C3E9D229117C795854F389C4D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_InvestmentIncomeInterest_3C11A1C3E9D229117C795854F389C4D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_91B449401CA96164DB295854F389CBE8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_InterestExpense_91B449401CA96164DB295854F389CBE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GainLossOnInvestments" xlink:label="loc_us-gaap_GainLossOnInvestments_374FEDD0B3B9551230215854F3899741" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_GainLossOnInvestments_374FEDD0B3B9551230215854F3899741" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_801C6EDFD938A79CFDCE5854F389AA45" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_801C6EDFD938A79CFDCE5854F389AA45" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_DDB6D7515D3091FE9F0D5854F389218A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_DDB6D7515D3091FE9F0D5854F389218A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueOptionChangesInFairValueGainLoss1" xlink:label="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_6D6BD1F9EB6731A27B4A5854F398F8F6" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_FairValueOptionChangesInFairValueGainLoss1_6D6BD1F9EB6731A27B4A5854F398F8F6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability" xlink:label="loc_abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability_7402B8940A4FAC3D8D3B5854F3983917" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_abus_IncreaseDecreaseInFairValueOfContingentConsiderationLiability_7402B8940A4FAC3D8D3B5854F3983917" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NonoperatingIncomeExpense" xlink:label="loc_us-gaap_NonoperatingIncomeExpense_41D927AE4514A061769D5854F398DF5A" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NonoperatingIncomeExpenseAbstract_00A91234F5C80D7954415854F38903E8" xlink:to="loc_us-gaap_NonoperatingIncomeExpense_41D927AE4514A061769D5854F398DF5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_E4E7B6EC0A086BD66CFC5854F3989DD5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_E4E7B6EC0A086BD66CFC5854F3989DD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_D6F74E20B2266D7BECD55854F39856EF" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_D6F74E20B2266D7BECD55854F39856EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_73732854BDE245066C4E5854F398CEBC" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_NetIncomeLoss_73732854BDE245066C4E5854F398CEBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockDividendsAndOtherAdjustmentsAbstract" xlink:label="loc_us-gaap_PreferredStockDividendsAndOtherAdjustmentsAbstract_23A29BADCAE93EE4383C5854F398ECE6" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_PreferredStockDividendsAndOtherAdjustmentsAbstract_23A29BADCAE93EE4383C5854F398ECE6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockDividendsAndOtherAdjustments" xlink:label="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_88D905459247BD6C56925854F398E01D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PreferredStockDividendsAndOtherAdjustmentsAbstract_23A29BADCAE93EE4383C5854F398ECE6" xlink:to="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_88D905459247BD6C56925854F398E01D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_D368C4B8F7E353E368715854F39851BD" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_D368C4B8F7E353E368715854F39851BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDilutedAbstract_C69D5B2CF1B06D9878A55854F3984EC4" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDilutedAbstract_C69D5B2CF1B06D9878A55854F3984EC4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_62AF914F450AECDCFCC25854F398A064" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAndDilutedAbstract_C69D5B2CF1B06D9878A55854F3984EC4" xlink:to="loc_us-gaap_EarningsPerShareBasic_62AF914F450AECDCFCC25854F398A064" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_833957684DB239C741525854F39867A6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicAndDilutedAbstract_C69D5B2CF1B06D9878A55854F3984EC4" xlink:to="loc_us-gaap_EarningsPerShareDiluted_833957684DB239C741525854F39867A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_7DDC6213B9EF972011A35854F398869E" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_7DDC6213B9EF972011A35854F398869E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_458A58A837610DAB95C75854F39887E2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_7DDC6213B9EF972011A35854F398869E" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_458A58A837610DAB95C75854F39887E2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_6EEE0393F8D0D26EF1355854F3983DB8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract_7DDC6213B9EF972011A35854F398869E" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_6EEE0393F8D0D26EF1355854F3983DB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAbstract" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_5105F16D7FE7C65E44315854F3982EE8" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_5105F16D7FE7C65E44315854F3982EE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_1DA846369047233950395854F3981EBC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_5105F16D7FE7C65E44315854F3982EE8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax_1DA846369047233950395854F3981EBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_67997970AC14B0A94B6C5854F398280B" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_051D37ACFE04E74389BF5854F389229A" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_67997970AC14B0A94B6C5854F398280B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ContingenciesAndCommitments" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F592608ED9384ECF20F4F28DC73899C7" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_D819246B3B22F6C9CA4CF28DC738302F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_F592608ED9384ECF20F4F28DC73899C7" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_D819246B3B22F6C9CA4CF28DC738302F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsMinimumRentAndEstimatedOperatingCostCommitmentNetOfLeaseInducementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_70AE6D7A31BDDA2397E7402213BF7F4C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears_70AE6D7A31BDDA2397E7402213BF7F4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_D727B02AF5279BEF6969402213BFA8CA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears_D727B02AF5279BEF6969402213BFA8CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_3A256BA39A072FF23F30402213BFC5B7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears_3A256BA39A072FF23F30402213BFC5B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_49AE013F852AEAEF5C7E402213BFB3E0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter_49AE013F852AEAEF5C7E402213BFB3E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:label="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_E55F4EBEF7DC18006A13402213BF6E4B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_899CB4557BE8BFFD3659402213BFE2CD" xlink:to="loc_us-gaap_OperatingLeasesFutureMinimumPaymentsDue_E55F4EBEF7DC18006A13402213BF6E4B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_5D755C03A3439BDD0D0158545E7FDB6C" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ContingenciesandCommitmentsTable" xlink:label="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_5D755C03A3439BDD0D0158545E7FDB6C" xlink:to="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_F93185DA41BCBD99E06F58545E85FC35" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_srt_ProductOrServiceAxis_F93185DA41BCBD99E06F58545E85FC35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_E3F90C077D7B6E616B7158545E8648A0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_F93185DA41BCBD99E06F58545E85FC35" xlink:to="loc_srt_ProductsAndServicesDomain_E3F90C077D7B6E616B7158545E8648A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RoyaltyMember" xlink:label="loc_us-gaap_RoyaltyMember_765AFD81F6469B9B947C58545E867645" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_E3F90C077D7B6E616B7158545E8648A0" xlink:to="loc_us-gaap_RoyaltyMember_765AFD81F6469B9B947C58545E867645" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LicenseMember" xlink:label="loc_us-gaap_LicenseMember_9F48EFB7663C05ABBE4458545E874F86" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_E3F90C077D7B6E616B7158545E8648A0" xlink:to="loc_us-gaap_LicenseMember_9F48EFB7663C05ABBE4458545E874F86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_58B83064148494B42F8A58545E8810E2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_srt_CounterpartyNameAxis_58B83064148494B42F8A58545E8810E2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_99C64BB91B7378F89F6158545E88A1F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_58B83064148494B42F8A58545E8810E2" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_99C64BB91B7378F89F6158545E88A1F8" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_BlumbergandDrexelMember" xlink:label="loc_abus_BlumbergandDrexelMember_E97783F680143B6F29CC58545E88C4AE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_99C64BB91B7378F89F6158545E88A1F8" xlink:to="loc_abus_BlumbergandDrexelMember_E97783F680143B6F29CC58545E88C4AE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_BlumbergMember" xlink:label="loc_abus_BlumbergMember_0F499D38EA71FF18C9D058545E88CAAC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_99C64BB91B7378F89F6158545E88A1F8" xlink:to="loc_abus_BlumbergMember_0F499D38EA71FF18C9D058545E88CAAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_F6FE00984BC1341888F758545E894FC4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_srt_LitigationCaseAxis_F6FE00984BC1341888F758545E894FC4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_28949FF9D239AEEC528F58545E8958AA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_F6FE00984BC1341888F758545E894FC4" xlink:to="loc_srt_LitigationCaseTypeDomain_28949FF9D239AEEC528F58545E8958AA" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ArbitrationWithTheUniversityOfBritishColumbiaMember" xlink:label="loc_abus_ArbitrationWithTheUniversityOfBritishColumbiaMember_F7A074D120107409195158545E89C6C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_28949FF9D239AEEC528F58545E8958AA" xlink:to="loc_abus_ArbitrationWithTheUniversityOfBritishColumbiaMember_F7A074D120107409195158545E89C6C4" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_4537013B9A8693803F9258545E891FEA" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_dei_LegalEntityAxis_4537013B9A8693803F9258545E891FEA" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_E4C8B867DBC3121686F058545E8A6140" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_4537013B9A8693803F9258545E891FEA" xlink:to="loc_dei_EntityDomain_E4C8B867DBC3121686F058545E8A6140" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ArbutusInc.Member" xlink:label="loc_abus_ArbutusInc.Member_AC51CB031D2D6BDF030A58545E8A439A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_E4C8B867DBC3121686F058545E8A6140" xlink:to="loc_abus_ArbutusInc.Member_AC51CB031D2D6BDF030A58545E8A439A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_2155EBE3434754B50B5958545E8ACF8C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_2155EBE3434754B50B5958545E8ACF8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F76BBFB6709CBE23C2FC58545E8A9CCE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_2155EBE3434754B50B5958545E8ACF8C" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F76BBFB6709CBE23C2FC58545E8A9CCE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EnantigenMember" xlink:label="loc_abus_EnantigenMember_6173ECEC85E8811BA11158545E8BA0C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F76BBFB6709CBE23C2FC58545E8A9CCE" xlink:to="loc_abus_EnantigenMember_6173ECEC85E8811BA11158545E8BA0C4" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ContingenciesandCommitmentsLineItems" xlink:label="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsTable_CC9AB3F90F431D24A0C658545E823979" xlink:to="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingLeasesRentExpenseNet" xlink:label="loc_us-gaap_OperatingLeasesRentExpenseNet_0B544042B543E3485D1158545E8BA5D3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_OperatingLeasesRentExpenseNet_0B544042B543E3485D1158545E8BA5D3" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PercentOfCostsFundedByTPC" xlink:label="loc_abus_PercentOfCostsFundedByTPC_9A117C064D131EC8241158545E8B268C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_PercentOfCostsFundedByTPC_9A117C064D131EC8241158545E8B268C" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_MaximumContributionForProduct" xlink:label="loc_abus_MaximumContributionForProduct_87287CACD371CC32318958545E8CC65F" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_MaximumContributionForProduct_87287CACD371CC32318958545E8CC65F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_CumulativeContributionforProduct" xlink:label="loc_abus_CumulativeContributionforProduct_FE1DD8A1424A03B9909258545E8CD0ED" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_CumulativeContributionforProduct_FE1DD8A1424A03B9909258545E8CD0ED" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoyaltyGuaranteesCommitmentsPercentage" xlink:label="loc_abus_RoyaltyGuaranteesCommitmentsPercentage_7D55EBBAB71D002E256558545E8CE7B2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_RoyaltyGuaranteesCommitmentsPercentage_7D55EBBAB71D002E256558545E8CE7B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_C040FF9778750AE8EE4F58545E8CE8EA" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax_C040FF9778750AE8EE4F58545E8CE8EA" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoyaltyPayable" xlink:label="loc_abus_RoyaltyPayable_043DD1A6B8D16F0387B858545E8C6902" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_RoyaltyPayable_043DD1A6B8D16F0387B858545E8C6902" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoyaltiesPaidOrAccrued" xlink:label="loc_abus_RoyaltiesPaidOrAccrued_56E1B5DD615D29ADF83E58545E8C88F9" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_RoyaltiesPaidOrAccrued_56E1B5DD615D29ADF83E58545E8C88F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractualObligation" xlink:label="loc_us-gaap_ContractualObligation_A2A5AA7B14121330DB1858545E8DC50C" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_ContractualObligation_A2A5AA7B14121330DB1858545E8DC50C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LossContingencyDamagesSoughtValue" xlink:label="loc_us-gaap_LossContingencyDamagesSoughtValue_D9DC1D5ABCFF174C45C358545E8D5C1A" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_LossContingencyDamagesSoughtValue_D9DC1D5ABCFF174C45C358545E8D5C1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_24B8388D95BD2E8A0CDC58545E8D6D43" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_24B8388D95BD2E8A0CDC58545E8D6D43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_39DABE200386D6C1090358545E8D83A5" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_39DABE200386D6C1090358545E8D83A5" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Numberofseriesofcompounds" xlink:label="loc_abus_Numberofseriesofcompounds_80CE576C921F6E714C5F58545E8DB660" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_Numberofseriesofcompounds_80CE576C921F6E714C5F58545E8DB660" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_4C32B155BA1677473C9658545E8D5535" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_4C32B155BA1677473C9658545E8D5535" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense" xlink:label="loc_abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense_C4901A232D39CD84A12958545E8E454C" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_LicenseAgreementMaximumDevelopmentAndRegulatoryMilestonePaymentsPerLicense_C4901A232D39CD84A12958545E8E454C" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense" xlink:label="loc_abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense_8A977E0EA5595C4F691758545E8ED3A6" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_LicenseAgreementMaximumSalesPerformanceMilestonePaymentsPerLicense_8A977E0EA5595C4F691758545E8ED3A6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ContractualObligationAmountOfResearchFundingPerYear" xlink:label="loc_abus_ContractualObligationAmountOfResearchFundingPerYear_C844A477F0126B1C7AAE58545E8E6E6E" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ContractualObligationAmountOfResearchFundingPerYear_C844A477F0126B1C7AAE58545E8E6E6E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingPeriod" xlink:label="loc_abus_ResearchFundingPeriod_73BE1789F4EED55842E258545E8E2011" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingPeriod_73BE1789F4EED55842E258545E8E2011" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingPeriodRenewableOption" xlink:label="loc_abus_ResearchFundingPeriodRenewableOption_06EC5777E2E229EF685B58545E8EEB51" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingPeriodRenewableOption_06EC5777E2E229EF685B58545E8EEB51" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment_376E5539EA49203E310158545E8E106E" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseUpfrontPayment_376E5539EA49203E310158545E8E106E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments_5751A1617DDC8E0598BA58545E8F6C17" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumDevelopmentAndRegulatoryMilestonePayments_5751A1617DDC8E0598BA58545E8F6C17" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments" xlink:label="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments_E57C9C191F947034D75458545E8F1B48" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingAgreementRightToObtainExclusiveLicenseMaximumCommercializationMilestonePayments_E57C9C191F947034D75458545E8F1B48" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchFundingPeriodNumberofRenewableOptions" xlink:label="loc_abus_ResearchFundingPeriodNumberofRenewableOptions_81752BD9234AA36102F658545E8F6CB3" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ContingenciesandCommitmentsLineItems_54B8A5E235553C31F75458545E8B5701" xlink:to="loc_abus_ResearchFundingPeriodNumberofRenewableOptions_81752BD9234AA36102F658545E8F6CB3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ContingenciesAndCommitmentsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_564ECF5C07FDAA1CA7A0AD3F9C28C687" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_24E7134D1F43B18FA0BAAD3F9C2817BD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_564ECF5C07FDAA1CA7A0AD3F9C28C687" xlink:to="loc_us-gaap_ScheduleOfFutureMinimumRentalPaymentsForOperatingLeasesTableTextBlock_24E7134D1F43B18FA0BAAD3F9C2817BD" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/DocumentAndEntityInformation" xlink:type="extended">
    <link:loc xlink:href="abus-20181231.xsd#abus_DocumentAndEntityInformationAbstract" xlink:label="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:type="locator" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityRegistrantName" xlink:label="loc_dei_EntityRegistrantName_43419A2D5427AB2542842CDD371A6A7B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityRegistrantName_43419A2D5427AB2542842CDD371A6A7B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentType" xlink:label="loc_dei_DocumentType_816D65D248E724EC718E2CDD371A24E8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_DocumentType_816D65D248E724EC718E2CDD371A24E8" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_CurrentFiscalYearEndDate" xlink:label="loc_dei_CurrentFiscalYearEndDate_33226A3866C869BDCD142CDD371AD250" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_CurrentFiscalYearEndDate_33226A3866C869BDCD142CDD371AD250" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCommonStockSharesOutstanding" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_3BD48459D79E8FEB4A282CDD371A05E5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_3BD48459D79E8FEB4A282CDD371A05E5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityPublicFloat" xlink:label="loc_dei_EntityPublicFloat_33FA244FFF0C1FE0B0E82CDD371AD7A5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityPublicFloat_33FA244FFF0C1FE0B0E82CDD371AD7A5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_AmendmentFlag" xlink:label="loc_dei_AmendmentFlag_3A0C1D784D9309D4473A2CDD371B1D15" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_AmendmentFlag_3A0C1D784D9309D4473A2CDD371B1D15" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCentralIndexKey" xlink:label="loc_dei_EntityCentralIndexKey_B5B7D5168379F0908F4A2CDD371BFCA1" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityCentralIndexKey_B5B7D5168379F0908F4A2CDD371BFCA1" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityCurrentReportingStatus" xlink:label="loc_dei_EntityCurrentReportingStatus_04321B82FC3A1EDA6D932CDD371BDFC1" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityCurrentReportingStatus_04321B82FC3A1EDA6D932CDD371BDFC1" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityVoluntaryFilers" xlink:label="loc_dei_EntityVoluntaryFilers_517349A48D41A39447BF2CDD371BC30B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityVoluntaryFilers_517349A48D41A39447BF2CDD371BC30B" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityFilerCategory" xlink:label="loc_dei_EntityFilerCategory_C78C714835AC18F109D32CDD371B7D01" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityFilerCategory_C78C714835AC18F109D32CDD371B7D01" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityWellKnownSeasonedIssuer" xlink:label="loc_dei_EntityWellKnownSeasonedIssuer_6963983409C51289B0CA2CDD371C25AE" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityWellKnownSeasonedIssuer_6963983409C51289B0CA2CDD371C25AE" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntitySmallBusiness" xlink:label="loc_dei_EntitySmallBusiness_4137CB4FC91CCE88AA5A2CDD371CA933" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntitySmallBusiness_4137CB4FC91CCE88AA5A2CDD371CA933" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityEmergingGrowthCompany" xlink:label="loc_dei_EntityEmergingGrowthCompany_499384BC8C5EE868C5902CDD371CDAC5" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityEmergingGrowthCompany_499384BC8C5EE868C5902CDD371CDAC5" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityShellCompany" xlink:label="loc_dei_EntityShellCompany_0ACFB0A7ED08895EB38B2CDD371CFAC2" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_EntityShellCompany_0ACFB0A7ED08895EB38B2CDD371CFAC2" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentPeriodEndDate" xlink:label="loc_dei_DocumentPeriodEndDate_58600739D586FA1E352B2CDD371CB4D2" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_DocumentPeriodEndDate_58600739D586FA1E352B2CDD371CB4D2" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentFiscalYearFocus" xlink:label="loc_dei_DocumentFiscalYearFocus_12B8D3F8319B4D72358C2CDD371C84AC" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_DocumentFiscalYearFocus_12B8D3F8319B4D72358C2CDD371C84AC" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_DocumentFiscalPeriodFocus" xlink:label="loc_dei_DocumentFiscalPeriodFocus_870CE0B93F84EA0172D72CDD371CE54B" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_DocumentAndEntityInformationAbstract_C2FC460CCF29F6DCAC752CDD3719F908" xlink:to="loc_dei_DocumentFiscalPeriodFocus_870CE0B93F84EA0172D72CDD371CE54B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestment" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_97887B386AEF5898439A2C856823F5C9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsDisclosureTextBlock" xlink:label="loc_us-gaap_EquityMethodInvestmentsDisclosureTextBlock_BB1031E2720BD38487A12C8568239FE5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_97887B386AEF5898439A2C856823F5C9" xlink:to="loc_us-gaap_EquityMethodInvestmentsDisclosureTextBlock_BB1031E2720BD38487A12C8568239FE5" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestmentBalanceSheetOfEquityMethodInvestmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_18C5EBD0BAB3E96811E62CDD364ED717" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_323DCA60C28109DCBD272CDD364E441C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_18C5EBD0BAB3E96811E62CDD364ED717" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_323DCA60C28109DCBD272CDD364E441C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_49BF2FC740357EE82F702CDD364EB6D2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_323DCA60C28109DCBD272CDD364E441C" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_49BF2FC740357EE82F702CDD364EB6D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_F90B770875D93039E0F42CDD364FB538" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_49BF2FC740357EE82F702CDD364EB6D2" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_F90B770875D93039E0F42CDD364FB538" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_A0037405337D248A04372CDD364F2422" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_F90B770875D93039E0F42CDD364FB538" xlink:to="loc_abus_GenevantSciencesCorporationMember_A0037405337D248A04372CDD364F2422" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_C8998BAEA8ADC7168DCF2CDD364F6A7A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_323DCA60C28109DCBD272CDD364E441C" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_C8998BAEA8ADC7168DCF2CDD364F6A7A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_C8998BAEA8ADC7168DCF2CDD364F6A7A" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentAssets" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentAssets_9E10503499695D201EBD2CDD364FB4B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentAssets_9E10503499695D201EBD2CDD364FB4B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentAssets" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentAssets_593452BB472D7806959F2CDD3650251A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentAssets_593452BB472D7806959F2CDD3650251A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAssets" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAssets_192DAD84D94465D459E12CDD365022BF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAssets_192DAD84D94465D459E12CDD365022BF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentLiabilities" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentLiabilities_AD13A833347E243128CB2CDD3650790D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationCurrentLiabilities_AD13A833347E243128CB2CDD3650790D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentLiabilities" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentLiabilities_AAE0123AE609DC020B822CDD3650A8E5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNoncurrentLiabilities_AAE0123AE609DC020B822CDD3650A8E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationEquity" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationEquity_45709C551F962AFC6FF62CDD36517A7B" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationEquity_45709C551F962AFC6FF62CDD36517A7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationLiabilitiesAndEquity" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationLiabilitiesAndEquity_32BCBBAC549A8B52FCE42CDD3651C130" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationAbstract_3CC2DEC89B71AB1CAADC2CDDCB65FE65" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationLiabilitiesAndEquity_32BCBBAC549A8B52FCE42CDD3651C130" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestmentNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_C5AF277BE06FD7C1B2572CDD365D4C53" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_97267F513A4F9E52AF6B2CDD365D5891" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_C5AF277BE06FD7C1B2572CDD365D4C53" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_97267F513A4F9E52AF6B2CDD365D5891" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_2DFAF6293DFEAF09FA1E2CDD365EE05C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_97267F513A4F9E52AF6B2CDD365D5891" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_2DFAF6293DFEAF09FA1E2CDD365EE05C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_0CD295E94ECEE5A75F482CDD365EB9E8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_2DFAF6293DFEAF09FA1E2CDD365EE05C" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_0CD295E94ECEE5A75F482CDD365EB9E8" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_5A238CE5FE4B9C999EA22CDD365FE927" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_0CD295E94ECEE5A75F482CDD365EB9E8" xlink:to="loc_abus_GenevantSciencesCorporationMember_5A238CE5FE4B9C999EA22CDD365FE927" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_6F66C18AA4C852C5D80A2CDD365DC77C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_97267F513A4F9E52AF6B2CDD365D5891" xlink:to="loc_dei_LegalEntityAxis_6F66C18AA4C852C5D80A2CDD365DC77C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_6C804DFF8EC8380E0C4A2CDD365E28B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_6F66C18AA4C852C5D80A2CDD365DC77C" xlink:to="loc_dei_EntityDomain_6C804DFF8EC8380E0C4A2CDD365E28B6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoivantSciencesLtdMember" xlink:label="loc_abus_RoivantSciencesLtdMember_C8B779E1743C5A1F5B302CDD365EDAC4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_6C804DFF8EC8380E0C4A2CDD365E28B6" xlink:to="loc_abus_RoivantSciencesLtdMember_C8B779E1743C5A1F5B302CDD365EDAC4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_97267F513A4F9E52AF6B2CDD365D5891" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentPropertyContribution" xlink:label="loc_abus_EquityMethodInvestmentPropertyContribution_AA97FA736582D26B1C962CDD365FE424" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_abus_EquityMethodInvestmentPropertyContribution_AA97FA736582D26B1C962CDD365FE424" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsToAcquireEquityMethodInvestments" xlink:label="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_8965A6B802BF1F31AA7B2CDD365F3089" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_us-gaap_PaymentsToAcquireEquityMethodInvestments_8965A6B802BF1F31AA7B2CDD365F3089" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentCommittedContribution" xlink:label="loc_abus_EquityMethodInvestmentCommittedContribution_364AB85DDF3F01A698082CDD366000CD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_abus_EquityMethodInvestmentCommittedContribution_364AB85DDF3F01A698082CDD366000CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_F94170A197DDA3853CAE2CDD36600031" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_F94170A197DDA3853CAE2CDD36600031" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GainLossOnInvestments" xlink:label="loc_us-gaap_GainLossOnInvestments_00B440ACE2EB0A99D2242CDD36604A4D" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_us-gaap_GainLossOnInvestments_00B440ACE2EB0A99D2242CDD36604A4D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillTransfers" xlink:label="loc_us-gaap_GoodwillTransfers_8BC8B5B653375D0240992CDD366086C7" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_DFEE206981D187ED5C7E2CDD365F0049" xlink:to="loc_us-gaap_GoodwillTransfers_8BC8B5B653375D0240992CDD366086C7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestmentResultsOfOperationsOfEquityMethodInvestmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_2D58A4525BD9BB87C3AC2CDD36473E58" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_53F316F8E1E97803C74A2CDD3647C96E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_2D58A4525BD9BB87C3AC2CDD36473E58" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_53F316F8E1E97803C74A2CDD3647C96E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_E24BC12C9937499B1F3F2CDD3647C1C6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_53F316F8E1E97803C74A2CDD3647C96E" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_E24BC12C9937499B1F3F2CDD3647C1C6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_27C4EAC3BEC68FCFF6372CDD36486484" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_E24BC12C9937499B1F3F2CDD3647C1C6" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_27C4EAC3BEC68FCFF6372CDD36486484" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_3910BDDE6F3D74A744F32CDD3648B972" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_27C4EAC3BEC68FCFF6372CDD36486484" xlink:to="loc_abus_GenevantSciencesCorporationMember_3910BDDE6F3D74A744F32CDD3648B972" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_266856521D9C199F0B922CDD3648689D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_53F316F8E1E97803C74A2CDD3647C96E" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_266856521D9C199F0B922CDD3648689D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_266856521D9C199F0B922CDD3648689D" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationRevenue" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationRevenue_2D86DE402A23F4339E6D2CDD364887D5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationRevenue_2D86DE402A23F4339E6D2CDD364887D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationGrossProfitLoss" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationGrossProfitLoss_04B0428F5694BC418BA52CDD364968EF" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationGrossProfitLoss_04B0428F5694BC418BA52CDD364968EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeLossFromContinuingOperationsBeforeExtraordinaryItems" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeLossFromContinuingOperationsBeforeExtraordinaryItems_98C45152895E8A8AFEC52CDF53D18C75" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeLossFromContinuingOperationsBeforeExtraordinaryItems_98C45152895E8A8AFEC52CDF53D18C75" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss" xlink:label="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss_958FCFAEAF2D65E6EB7E2CDD3649EE44" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationIncomeStatementAbstract_DC3F7C0C6B158A85D92D2CDFB8E7C47E" xlink:to="loc_us-gaap_EquityMethodInvestmentSummarizedFinancialInformationNetIncomeLoss_958FCFAEAF2D65E6EB7E2CDD3649EE44" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestmentScheduleOfEquityInvestmentBalanceDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_F9AD03F818C59D30AFE0402215361C89" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_45BB8C629954F81173B740221536079B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_F9AD03F818C59D30AFE0402215361C89" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_45BB8C629954F81173B740221536079B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_BCA1F1AD61E131E824D0402215362F51" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_45BB8C629954F81173B740221536079B" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_BCA1F1AD61E131E824D0402215362F51" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_F3405B80EA9EF59BE90240221536E769" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_BCA1F1AD61E131E824D0402215362F51" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_F3405B80EA9EF59BE90240221536E769" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_911FC3DC2DAE3794405A40221536A346" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_F3405B80EA9EF59BE90240221536E769" xlink:to="loc_abus_GenevantSciencesCorporationMember_911FC3DC2DAE3794405A40221536A346" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_FEE0289D94F5F1F5BF9E40221546CB75" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_45BB8C629954F81173B740221536079B" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_FEE0289D94F5F1F5BF9E40221546CB75" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentRollForward" xlink:label="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_FEE0289D94F5F1F5BF9E40221546CB75" xlink:to="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_us-gaap_EquityMethodInvestments_105ECAE2AF613A28D415402215462331" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_us-gaap_EquityMethodInvestments_105ECAE2AF613A28D415402215462331" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentPropertyContribution" xlink:label="loc_abus_EquityMethodInvestmentPropertyContribution_D719CB4EB1103F7276D240221546E236" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_abus_EquityMethodInvestmentPropertyContribution_D719CB4EB1103F7276D240221546E236" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquityMethodInvestmentAdjustmentRelatedToShareBasedCompensation" xlink:label="loc_abus_EquityMethodInvestmentAdjustmentRelatedToShareBasedCompensation_4A81AC72DBADE6D326D440221546DB76" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_abus_EquityMethodInvestmentAdjustmentRelatedToShareBasedCompensation_4A81AC72DBADE6D326D440221546DB76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions_3A24B52AFC1E8E2C9E764022154685B5" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestmentsNetOfDividendsOrDistributions_3A24B52AFC1E8E2C9E764022154685B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromEquityMethodInvestments_E0F81F5CC808C6A883EE402215464362" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_us-gaap_IncomeLossFromEquityMethodInvestments_E0F81F5CC808C6A883EE402215464362" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncreaseDecreaseInEquityMethodInvestmentsForeignCurrencyTranslationAdjustments" xlink:label="loc_abus_IncreaseDecreaseInEquityMethodInvestmentsForeignCurrencyTranslationAdjustments_6551BCCCCD3E13D0F230402215465597" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_abus_IncreaseDecreaseInEquityMethodInvestmentsForeignCurrencyTranslationAdjustments_6551BCCCCD3E13D0F230402215465597" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_us-gaap_EquityMethodInvestments_C6982F514E7B60AAD80240221546D4F4" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_EquityMethodInvestmentRollForward_550D6176438816287D32402215460A70" xlink:to="loc_us-gaap_EquityMethodInvestments_C6982F514E7B60AAD80240221546D4F4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/EquityMethodInvestmentTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract" xlink:label="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_A27C5F0F91C149CDB5CC2C856821C525" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsTextBlock" xlink:label="loc_us-gaap_EquityMethodInvestmentsTextBlock_082BA1C9B81F3C6615932C856821F0FC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityMethodInvestmentsAndJointVenturesAbstract_A27C5F0F91C149CDB5CC2C856821C525" xlink:to="loc_us-gaap_EquityMethodInvestmentsTextBlock_082BA1C9B81F3C6615932C856821F0FC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_3E74CC904BEBAC93B1DC2C547B0426A6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_3199117D8BC57C47B0842C547B040449" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_3E74CC904BEBAC93B1DC2C547B0426A6" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_3199117D8BC57C47B0842C547B040449" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_6A877C026757DA8819894A826670CC0A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0918CE7107474966300F4A8266723741" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6A877C026757DA8819894A826670CC0A" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0918CE7107474966300F4A8266723741" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_E71F6237B1FEC71941834A8266738238" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0918CE7107474966300F4A8266723741" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_E71F6237B1FEC71941834A8266738238" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_6E796C8858FA637FECD04A8266739C98" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_E71F6237B1FEC71941834A8266738238" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_6E796C8858FA637FECD04A8266739C98" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_909409C802A87CA0EAC64A826674BD17" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_6E796C8858FA637FECD04A8266739C98" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_909409C802A87CA0EAC64A826674BD17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_11DE07038043999F8F954A8266746F77" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0918CE7107474966300F4A8266723741" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_11DE07038043999F8F954A8266746F77" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0617BEE7723274FEF22A4A826674FCA0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_11DE07038043999F8F954A8266746F77" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0617BEE7723274FEF22A4A826674FCA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_23BEBA7C11607463A3EC4A82667536C3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0617BEE7723274FEF22A4A826674FCA0" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_23BEBA7C11607463A3EC4A82667536C3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_39CBD8FBBACC69BE29294A826677D09B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0617BEE7723274FEF22A4A826674FCA0" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_39CBD8FBBACC69BE29294A826677D09B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_073796CA3A9E561A9D684A8266774843" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_0617BEE7723274FEF22A4A826674FCA0" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_073796CA3A9E561A9D684A8266774843" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_78E9D128CD88A9B540BF4A826677B5D3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_0918CE7107474966300F4A8266723741" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_78E9D128CD88A9B540BF4A826677B5D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_78E9D128CD88A9B540BF4A826677B5D3" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_86E5890615CDB4AD64FB4A82667864AA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_86E5890615CDB4AD64FB4A82667864AA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentsFairValueDisclosure" xlink:label="loc_us-gaap_InvestmentsFairValueDisclosure_15439F0F2AABD26CA02D4A82667829B0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:to="loc_us-gaap_InvestmentsFairValueDisclosure_15439F0F2AABD26CA02D4A82667829B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedInvestmentsAtFairValue" xlink:label="loc_us-gaap_RestrictedInvestmentsAtFairValue_E639C96856449231D1894A82667884E1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:to="loc_us-gaap_RestrictedInvestmentsAtFairValue_E639C96856449231D1894A82667884E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_84C8E40BDB3CD6321CD24A826678A299" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_3ED29232F37CF04FED064A826677F74C" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_84C8E40BDB3CD6321CD24A826678A299" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_281241970E96DC40585E4A8266792F20" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_78E9D128CD88A9B540BF4A826677B5D3" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_281241970E96DC40585E4A8266792F20" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_40EB1617346E29C0301B4A8266796A80" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_281241970E96DC40585E4A8266792F20" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_40EB1617346E29C0301B4A8266796A80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_015C5B523AF9F19CFE1B4A82667926C5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_281241970E96DC40585E4A8266792F20" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_015C5B523AF9F19CFE1B4A82667926C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_AA1D935292DAFED042124A8266790A02" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosureAbstract_281241970E96DC40585E4A8266792F20" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_AA1D935292DAFED042124A8266790A02" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfContingentConsiderationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_8E5BFB8158462601A0C04A82DFF943FA" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward" xlink:label="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_5183ABD3C2C9DC27D1874A82DFFCF8F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_8E5BFB8158462601A0C04A82DFF943FA" xlink:to="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_5183ABD3C2C9DC27D1874A82DFFCF8F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_DB2BFA7BCF531025FBD44A82DFFCA8CD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_5183ABD3C2C9DC27D1874A82DFFCF8F4" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_DB2BFA7BCF531025FBD44A82DFFCA8CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_170AFD6E6631C57018F84A82DFFC7804" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_5183ABD3C2C9DC27D1874A82DFFCF8F4" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_170AFD6E6631C57018F84A82DFFC7804" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_CD990258579A00AFF7AD4A82DFFC6197" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_5183ABD3C2C9DC27D1874A82DFFCF8F4" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_CD990258579A00AFF7AD4A82DFFC6197" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfLiabilitiesClassifiedAsStockOptionDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_FA3D64C65224D449F6B84B42EA9E5D89" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_99403D98701DE484EA224B42EAA16F06" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_FA3D64C65224D449F6B84B42EA9E5D89" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_99403D98701DE484EA224B42EAA16F06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_AB9E4256AFF86AD982BF4B42EAA23293" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_99403D98701DE484EA224B42EAA16F06" xlink:to="loc_us-gaap_AwardTypeAxis_AB9E4256AFF86AD982BF4B42EAA23293" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1893EA9743ECAAD301784B42EAA3E87F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_AB9E4256AFF86AD982BF4B42EAA23293" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1893EA9743ECAAD301784B42EAA3E87F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_29181814DDC6369335AA4B42EAA305A4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1893EA9743ECAAD301784B42EAA3E87F" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_29181814DDC6369335AA4B42EAA305A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_80FB20C7047569AFD26E4B42EAA4F7B9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_99403D98701DE484EA224B42EAA16F06" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_80FB20C7047569AFD26E4B42EAA4F7B9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward" xlink:label="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_80FB20C7047569AFD26E4B42EAA4F7B9" xlink:to="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_5B0168F04F8BE5C4A66A4B42EAA4A4C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_5B0168F04F8BE5C4A66A4B42EAA4A4C4" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodFairValue" xlink:label="loc_abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodFairValue_5D6736E3B37C775099F54B42EE36BE97" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:to="loc_abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsExercisesinPeriodFairValue_5D6736E3B37C775099F54B42EE36BE97" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions" xlink:label="loc_abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions_2C5447C878E5597C96404B42EAA7477E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:to="loc_abus_IncreaseDecreaseinFairValueofLiabilityClassifiedOptions_2C5447C878E5597C96404B42EAA7477E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_D927C1DF7AAB281BE3EC4B42EAA7909B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_99C151465CD3F951FCAF4B42EAA47370" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_D927C1DF7AAB281BE3EC4B42EAA7909B" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsChangesInFairValueOfWarrantsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_EE8DCC52FCDA50B3B3B22C616A96F9CD" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward" xlink:label="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_EE8DCC52FCDA50B3B3B22C616A96F9CD" xlink:to="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WarrantsNotSettleableInCashFairValueDisclosure" xlink:label="loc_us-gaap_WarrantsNotSettleableInCashFairValueDisclosure_3B2F85BD7A0C8915F4B02C616D3CD732" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:to="loc_us-gaap_WarrantsNotSettleableInCashFairValueDisclosure_3B2F85BD7A0C8915F4B02C616D3CD732" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueOfWarrantsExercisedInThePeriod" xlink:label="loc_abus_FairValueOfWarrantsExercisedInThePeriod_3FDDF42C61E93543E5032C616D47071A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:to="loc_abus_FairValueOfWarrantsExercisedInThePeriod_3FDDF42C61E93543E5032C616D47071A" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncreaseDecreaseInValueOfWarrants" xlink:label="loc_abus_IncreaseDecreaseInValueOfWarrants_E78074F35448B04B0B302C616D512F1A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:to="loc_abus_IncreaseDecreaseInValueOfWarrants_E78074F35448B04B0B302C616D512F1A" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueWarrantsForeignExchangeGainLoss" xlink:label="loc_abus_FairValueWarrantsForeignExchangeGainLoss_8D1936277F3FD8DF69232C616D5BAB15" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:to="loc_abus_FairValueWarrantsForeignExchangeGainLoss_8D1936277F3FD8DF69232C616D5BAB15" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WarrantsNotSettleableInCashFairValueDisclosure" xlink:label="loc_us-gaap_WarrantsNotSettleableInCashFairValueDisclosure_1D3C388BA524903378292C63AECCA72C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_FairValueLiabilitiesMeasuredonRecurringBasisRollForward_8E10EB28F9B1D0CED9AE2C650852A32E" xlink:to="loc_us-gaap_WarrantsNotSettleableInCashFairValueDisclosure_1D3C388BA524903378292C63AECCA72C" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_65D84D33354B07545A77402215C3C5D2" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_A230780D592F8340FD84402215C3F83E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_65D84D33354B07545A77402215C3C5D2" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_A230780D592F8340FD84402215C3F83E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_1531728DFE0A2B16D333402215C30BAC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_65D84D33354B07545A77402215C3C5D2" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_1531728DFE0A2B16D333402215C30BAC" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_6A60261935F43F665A562C547936CE05" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_6A98A9A5C9530906D3EE2C547937462E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6A60261935F43F665A562C547936CE05" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_6A98A9A5C9530906D3EE2C547937462E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ChangesInFairValueOfWarrantsTableTextBlock" xlink:label="loc_abus_ChangesInFairValueOfWarrantsTableTextBlock_B3EA6C1BF70CDE671D472C602AB634AE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6A60261935F43F665A562C547936CE05" xlink:to="loc_abus_ChangesInFairValueOfWarrantsTableTextBlock_B3EA6C1BF70CDE671D472C602AB634AE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ChangesInFairValueofLiabilityOptionTableTextBlock" xlink:label="loc_abus_ChangesInFairValueofLiabilityOptionTableTextBlock_21D7E741A731BEFC93DD2C547937B321" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6A60261935F43F665A562C547936CE05" xlink:to="loc_abus_ChangesInFairValueofLiabilityOptionTableTextBlock_21D7E741A731BEFC93DD2C547937B321" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_3D73E9F477D50EC814AB2C547937B467" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_6A60261935F43F665A562C547936CE05" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTextBlock_3D73E9F477D50EC814AB2C547937B467" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_1708AEC67A26FC5D25EEF28A787D28C9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_F0B6367529E42A9F4764F28A787DD8A0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_1708AEC67A26FC5D25EEF28A787D28C9" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_F0B6367529E42A9F4764F28A787DD8A0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IncomeTaxesDeferredTaxAssetsAndLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_4F1C3011054FAC45703B402213BFDC19" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ComponentsofDeferredTaxAssetsTable" xlink:label="loc_abus_ComponentsofDeferredTaxAssetsTable_DFF9D23187BF420C326D402213CF9314" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_4F1C3011054FAC45703B402213BFDC19" xlink:to="loc_abus_ComponentsofDeferredTaxAssetsTable_DFF9D23187BF420C326D402213CF9314" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_BF0B5AB810A4691022A5402213CFAB99" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsTable_DFF9D23187BF420C326D402213CF9314" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_BF0B5AB810A4691022A5402213CFAB99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_02A9FEDED9435490F1B4402213CF39C4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_BF0B5AB810A4691022A5402213CFAB99" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_02A9FEDED9435490F1B4402213CF39C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DomesticCountryMember" xlink:label="loc_us-gaap_DomesticCountryMember_EC6E0B2339A60C646F33402213D037B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_02A9FEDED9435490F1B4402213CF39C4" xlink:to="loc_us-gaap_DomesticCountryMember_EC6E0B2339A60C646F33402213D037B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StateAndLocalJurisdictionMember" xlink:label="loc_us-gaap_StateAndLocalJurisdictionMember_C4DD66B299C81A48B8E7402213D0A6B5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_02A9FEDED9435490F1B4402213CF39C4" xlink:to="loc_us-gaap_StateAndLocalJurisdictionMember_C4DD66B299C81A48B8E7402213D0A6B5" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ComponentsofDeferredTaxAssetsLineItems" xlink:label="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsTable_DFF9D23187BF420C326D402213CF9314" xlink:to="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_3CA286200B1C64E95F9D402213D054F8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_3CA286200B1C64E95F9D402213D054F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment" xlink:label="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_507CF41ED2B35D194433402213D0CEDD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsInProcessResearchAndDevelopment_507CF41ED2B35D194433402213D0CEDD" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_DeferredTaxAssetBookAmortizationInExcessOfTax" xlink:label="loc_abus_DeferredTaxAssetBookAmortizationInExcessOfTax_9924ABECB009A248CCCC402213D116E7" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_abus_DeferredTaxAssetBookAmortizationInExcessOfTax_9924ABECB009A248CCCC402213D116E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_EDE279060DD74106FDA7402213D10FCE" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_EDE279060DD74106FDA7402213D10FCE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_DeferredTaxAssetRevenueRecognizedForTaxPurposesInExcessOfRevenueRecognizedForAccountingPurposes" xlink:label="loc_abus_DeferredTaxAssetRevenueRecognizedForTaxPurposesInExcessOfRevenueRecognizedForAccountingPurposes_2DC4D5B9AB237EF4B847402213D1ECEE" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_abus_DeferredTaxAssetRevenueRecognizedForTaxPurposesInExcessOfRevenueRecognizedForAccountingPurposes_2DC4D5B9AB237EF4B847402213D1ECEE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_DeferredTaxAssetTaxValueInExcessOfAccountingValueInLeaseInducements" xlink:label="loc_abus_DeferredTaxAssetTaxValueInExcessOfAccountingValueInLeaseInducements_3AAB569C669FBC8C90F4402213D13E30" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_abus_DeferredTaxAssetTaxValueInExcessOfAccountingValueInLeaseInducements_3AAB569C669FBC8C90F4402213D13E30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsInvestments" xlink:label="loc_us-gaap_DeferredTaxAssetsInvestments_0280592073FE516B4D07402213D111E9" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsInvestments_0280592073FE516B4D07402213D111E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts_D4EE742C378E8450AA95402213D115E9" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts_D4EE742C378E8450AA95402213D115E9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_DeferredTaxAssetUpfrontLicenseFees" xlink:label="loc_abus_DeferredTaxAssetUpfrontLicenseFees_180C962983E59F39AAA0402213D209CE" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_abus_DeferredTaxAssetUpfrontLicenseFees_180C962983E59F39AAA0402213D209CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsEquityMethodInvestments" xlink:label="loc_us-gaap_DeferredTaxAssetsEquityMethodInvestments_F451D344338292EBA11940239EE3F017" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsEquityMethodInvestments_F451D344338292EBA11940239EE3F017" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOther" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_793B1239966FA79D9E56402213D26698" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_793B1239966FA79D9E56402213D26698" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsGross" xlink:label="loc_us-gaap_DeferredTaxAssetsGross_0B4523551F77AB4D8334402213D2A8F2" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsGross_0B4523551F77AB4D8334402213D2A8F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_DeferredTaxAssetsValuationAllowance_8641A17F540ED89D8EFB402213D2FF54" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxAssetsValuationAllowance_8641A17F540ED89D8EFB402213D2FF54" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxLiabilities" xlink:label="loc_us-gaap_DeferredTaxLiabilities_97B06E8952DAE215BD25402213D225B4" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_ComponentsofDeferredTaxAssetsLineItems_0350A6A8DC43D7B4B0C3402213D0D328" xlink:to="loc_us-gaap_DeferredTaxLiabilities_97B06E8952DAE215BD25402213D225B4" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IncomeTaxesIncomeTaxReconciliationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_17783C25BC58DCC2E782AD3F98A6DE55" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate_17783C25BC58DCC2E782AD3F98A6DE55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_B215D6FAE0A13982F539AD3F98A665B3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInEnactedTaxRate_B215D6FAE0A13982F539AD3F98A665B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationOtherAdjustments" xlink:label="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_0D3248371F5C7A8B757EAD3F98A68FFD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationOtherAdjustments_0D3248371F5C7A8B757EAD3F98A68FFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance" xlink:label="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_5644BF33CBD95B5FBC15AD3F98A6B6EF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance_5644BF33CBD95B5FBC15AD3F98A6B6EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential" xlink:label="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_BBB4C4F16261C9120434AD3F98A66EFF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationForeignIncomeTaxRateDifferential_BBB4C4F16261C9120434AD3F98A66EFF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_E32F46990EF5054B4271AD3F98A74173" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost_E32F46990EF5054B4271AD3F98A74173" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses" xlink:label="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_2FB5D04B9E68146B2458AD3F98A70407" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxReconciliationNondeductibleExpenseImpairmentLosses_2FB5D04B9E68146B2458AD3F98A70407" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_FB6D18579B5559FE49C3AD3F98A71047" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_BF3C4D4C0B8E56A171FBAD3F98A5CAC6" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_FB6D18579B5559FE49C3AD3F98A71047" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IncomeTaxesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_25AF6AF6A7D7A7377AC74021A6CDAB64" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncomeTaxesTable" xlink:label="loc_abus_IncomeTaxesTable_C9A5E5DDE92B00BC6F8B4021A6CD4CD1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_25AF6AF6A7D7A7377AC74021A6CDAB64" xlink:to="loc_abus_IncomeTaxesTable_C9A5E5DDE92B00BC6F8B4021A6CD4CD1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TaxCreditCarryforwardAxis" xlink:label="loc_us-gaap_TaxCreditCarryforwardAxis_0363BBA38109D56091F64021A6CE9A7B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesTable_C9A5E5DDE92B00BC6F8B4021A6CD4CD1" xlink:to="loc_us-gaap_TaxCreditCarryforwardAxis_0363BBA38109D56091F64021A6CE9A7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TaxCreditCarryforwardNameDomain" xlink:label="loc_us-gaap_TaxCreditCarryforwardNameDomain_0382F3CF45A91CCCB2934021A6CEACDC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TaxCreditCarryforwardAxis_0363BBA38109D56091F64021A6CE9A7B" xlink:to="loc_us-gaap_TaxCreditCarryforwardNameDomain_0382F3CF45A91CCCB2934021A6CEACDC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentCreditMember" xlink:label="loc_us-gaap_InvestmentCreditMember_F71F2758F3FFCAF475BF4021A6CF3A73" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TaxCreditCarryforwardNameDomain_0382F3CF45A91CCCB2934021A6CEACDC" xlink:to="loc_us-gaap_InvestmentCreditMember_F71F2758F3FFCAF475BF4021A6CF3A73" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchMember" xlink:label="loc_us-gaap_ResearchMember_B293603A917218BAE1CF4021A6CF127E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TaxCreditCarryforwardNameDomain_0382F3CF45A91CCCB2934021A6CEACDC" xlink:to="loc_us-gaap_ResearchMember_B293603A917218BAE1CF4021A6CF127E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_IncomeTaxesDetailsLineItems" xlink:label="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesTable_C9A5E5DDE92B00BC6F8B4021A6CD4CD1" xlink:to="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_B6BDDAA4463321B3D8254021A6D0354E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate_B6BDDAA4463321B3D8254021A6D0354E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxLiabilityProvisionalIncomeTaxBenefit" xlink:label="loc_abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxLiabilityProvisionalIncomeTaxBenefit_317D8578A56D11312F154021A6D1EDF2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxLiabilityProvisionalIncomeTaxBenefit_317D8578A56D11312F154021A6D1EDF2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxAssetProvisionalIncomeTaxExpense" xlink:label="loc_abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxAssetProvisionalIncomeTaxExpense_625DBF8221E993C8B91F4021A6D105FD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_abus_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxAssetProvisionalIncomeTaxExpense_625DBF8221E993C8B91F4021A6D105FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsDomestic" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsDomestic_7D95F5FB93FFD50011764021A6D17B5B" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsDomestic_7D95F5FB93FFD50011764021A6D17B5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal_55C6D9F39B2D57674FCD4021A6D1E6BB" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal_55C6D9F39B2D57674FCD4021A6D1E6BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_A581CC01494642897F7E4021A6D46691" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxCreditCarryforwardsResearch_A581CC01494642897F7E4021A6D46691" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwards" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_7C174D2A3FAEB3946CC34021A6D4FA78" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwards_7C174D2A3FAEB3946CC34021A6D4FA78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_9C6405B6777BA6BDA0064021A6D4E960" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_IncomeTaxesDetailsLineItems_55A036BDF12E82F98B3F4021A6D070B3" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsSubjectToExpiration_9C6405B6777BA6BDA0064021A6D4E960" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IncomeTaxesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_31EC54D710D2E1040A7AAD3F9983FA06" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_CEFCA4C655DCB384507AAD3F99834074" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_31EC54D710D2E1040A7AAD3F9983FA06" xlink:to="loc_us-gaap_ScheduleOfEffectiveIncomeTaxRateReconciliationTableTextBlock_CEFCA4C655DCB384507AAD3F99834074" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_FE507B2110A22A88FAC2AD3F9984DCD7" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_31EC54D710D2E1040A7AAD3F9983FA06" xlink:to="loc_us-gaap_ScheduleOfDeferredTaxAssetsAndLiabilitiesTableTextBlock_FE507B2110A22A88FAC2AD3F9984DCD7" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwill" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_48E4A2195C649DB7B80A2CDD3635D935" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_B6388C3BAD2B096B4FEF2CDD3635ABC2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_48E4A2195C649DB7B80A2CDD3635D935" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureTextBlock_B6388C3BAD2B096B4FEF2CDD3635ABC2" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_6054465A9A36FC66EE1F402214B9AC71" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_1AC906772EF619DCF6EE402214B9C770" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_6054465A9A36FC66EE1F402214B9AC71" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_1AC906772EF619DCF6EE402214B9C770" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_64BAA44322B0C0A5218C40A5DB89029D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_1AC906772EF619DCF6EE402214B9C770" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_64BAA44322B0C0A5218C40A5DB89029D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_4962BA9E47668E313F7D40A5DB8ED54F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_64BAA44322B0C0A5218C40A5DB89029D" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_4962BA9E47668E313F7D40A5DB8ED54F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_CFB3EAF62CF57E5808CF40A5DC68D54B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_4962BA9E47668E313F7D40A5DB8ED54F" xlink:to="loc_abus_GenevantSciencesCorporationMember_CFB3EAF62CF57E5808CF40A5DC68D54B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9B6DC2468D9C07035397402214B983EA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_1AC906772EF619DCF6EE402214B9C770" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9B6DC2468D9C07035397402214B983EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_198585F314D496F656D3402214B971E6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_9B6DC2468D9C07035397402214B983EA" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_198585F314D496F656D3402214B971E6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_STINGDrugCandidateMember" xlink:label="loc_abus_STINGDrugCandidateMember_7F5DAE53C2C7A6A06E0D402214B9B952" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_198585F314D496F656D3402214B971E6" xlink:to="loc_abus_STINGDrugCandidateMember_7F5DAE53C2C7A6A06E0D402214B9B952" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_1AC906772EF619DCF6EE402214B9C770" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill" xlink:label="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_69583A08E160B1F147BA402214B95E02" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_ImpairmentOfIntangibleAssetsExcludingGoodwill_69583A08E160B1F147BA402214B95E02" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxExpenseBenefitContinuingOperationsAdjustmentOfDeferredTaxAssetLiability" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsAdjustmentOfDeferredTaxAssetLiability_D60BFD432CFA6ACB56B8402214B90990" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefitContinuingOperationsAdjustmentOfDeferredTaxAssetLiability_D60BFD432CFA6ACB56B8402214B90990" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_75F5BE90BDAE6802A814402214B943B5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_75F5BE90BDAE6802A814402214B943B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NumberOfReportingUnits" xlink:label="loc_us-gaap_NumberOfReportingUnits_4ADE6A8E249453661B99402214B95A30" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_NumberOfReportingUnits_4ADE6A8E249453661B99402214B95A30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillTransfers" xlink:label="loc_us-gaap_GoodwillTransfers_8D2FA82241413151579F402214B9C51F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_GoodwillTransfers_8D2FA82241413151579F402214B9C51F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillImpairmentLoss" xlink:label="loc_us-gaap_GoodwillImpairmentLoss_861D3D8BC3D132046140402214B9F173" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_4F3888A7DFE79ABE3CFF402214B9D177" xlink:to="loc_us-gaap_GoodwillImpairmentLoss_861D3D8BC3D132046140402214B9F173" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillSummaryOfCarryingValueOfIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_A010B9689F29BF3332032CDD3627FA3D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_E914AA96BB2652D7B5F52CDD36272CC8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_A010B9689F29BF3332032CDD3627FA3D" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_E914AA96BB2652D7B5F52CDD36272CC8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_2CF9210253DD50CB9D842CDD3627AAF7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_E914AA96BB2652D7B5F52CDD36272CC8" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_2CF9210253DD50CB9D842CDD3627AAF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9EB607D83773C49F97772CDD36280206" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_2CF9210253DD50CB9D842CDD3627AAF7" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9EB607D83773C49F97772CDD36280206" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_InProcessResearchandDevelopmentImmuneModulatorsMember" xlink:label="loc_abus_InProcessResearchandDevelopmentImmuneModulatorsMember_5CC290E072B845ECEF0D2CDD3628A4A1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9EB607D83773C49F97772CDD36280206" xlink:to="loc_abus_InProcessResearchandDevelopmentImmuneModulatorsMember_5CC290E072B845ECEF0D2CDD3628A4A1" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_InProcessResearchandDevelopmentAntigenInhibitorsMember" xlink:label="loc_abus_InProcessResearchandDevelopmentAntigenInhibitorsMember_B96A5AB9C4AC0A3D66222CDD3628F8F2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9EB607D83773C49F97772CDD36280206" xlink:to="loc_abus_InProcessResearchandDevelopmentAntigenInhibitorsMember_B96A5AB9C4AC0A3D66222CDD3628F8F2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_InProcessResearchandDevelopmentcccDNASterilizersMember" xlink:label="loc_abus_InProcessResearchandDevelopmentcccDNASterilizersMember_570FD3F16E2D8BF65FC32CDD36287E5E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_9EB607D83773C49F97772CDD36280206" xlink:to="loc_abus_InProcessResearchandDevelopmentcccDNASterilizersMember_570FD3F16E2D8BF65FC32CDD36287E5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_E8BC4041BA2657A521542CDD36292ACC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTable_E914AA96BB2652D7B5F52CDD36272CC8" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_E8BC4041BA2657A521542CDD36292ACC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_49FB4B4BEBB2E7BE39952CDD3629F2B0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassLineItems_E8BC4041BA2657A521542CDD36292ACC" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_49FB4B4BEBB2E7BE39952CDD3629F2B0" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/IntangibleAssetsAndGoodwillTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_64A5D2201AF49201A8D82CDD363314F1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_07FC82D2331BA60A0AA52CDD36334D28" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract_64A5D2201AF49201A8D82CDD363314F1" xlink:to="loc_us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock_07FC82D2331BA60A0AA52CDD36334D28" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/InterimFinancialDataUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_DC932AB29679D4088CD7F28A7A32A841" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_QuarterlyFinancialInformationTextBlock" xlink:label="loc_us-gaap_QuarterlyFinancialInformationTextBlock_CEF24D22E682880366C6F28A7A3302FB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_DC932AB29679D4088CD7F28A7A32A841" xlink:to="loc_us-gaap_QuarterlyFinancialInformationTextBlock_CEF24D22E682880366C6F28A7A3302FB" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/InterimFinancialDataUnauditedDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_Revenues" xlink:label="loc_us-gaap_Revenues_E877BE9DF03FBA9885FA4022138AB5C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_Revenues_E877BE9DF03FBA9885FA4022138AB5C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_D99DE21F54D2BCEE88994022138ADED4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_OperatingIncomeLoss_D99DE21F54D2BCEE88994022138ADED4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_4D09CA8EB1278ED3795C4022138BA9E4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/netLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_NetIncomeLoss_4D09CA8EB1278ED3795C4022138BA9E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_763D789B96FCBC850C57405F5B77EA02" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_763D789B96FCBC850C57405F5B77EA02" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="loc_us-gaap_EarningsPerShareBasic_2BCFF31E6D9D2150665D40624106BC4C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_EarningsPerShareBasic_2BCFF31E6D9D2150665D40624106BC4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="loc_us-gaap_EarningsPerShareDiluted_A88C9F0626FE397107E64062419F0E16" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_EarningsPerShareDiluted_A88C9F0626FE397107E64062419F0E16" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_15BDF7EE1A81076FE9AD4062B7150E4E" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_AE59ED17BF735AF4F1734022138A99EB" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_15BDF7EE1A81076FE9AD4062B7150E4E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/InterimFinancialDataUnauditedTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_QuarterlyFinancialInformationDisclosureAbstract" xlink:label="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_FD7892B80267C0547E2AAD3F9AAC1340" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_8845F723342CE425589AAD3F9AACCB40" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_QuarterlyFinancialInformationDisclosureAbstract_FD7892B80267C0547E2AAD3F9AAC1340" xlink:to="loc_us-gaap_ScheduleOfQuarterlyFinancialInformationTableTextBlock_8845F723342CE425589AAD3F9AACCB40" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/LoanPayable" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_67954B6E005936D7374E2CDD35FD9C63" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureTextBlock" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_5777F9F9515A1A97F4BF2CDD35FDFD3D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_67954B6E005936D7374E2CDD35FD9C63" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_5777F9F9515A1A97F4BF2CDD35FDFD3D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/LoanPayableDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtDisclosureAbstract" xlink:label="loc_us-gaap_DebtDisclosureAbstract_FF956AD50D81C88B22472CDD35F5064C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_FF956AD50D81C88B22472CDD35F5064C" xlink:to="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_4CDC4A8F56219FEB91FB2CDD35F794FE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_4CDC4A8F56219FEB91FB2CDD35F794FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_FD4F914A6B33D95F792A2CDD35F72A50" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_4CDC4A8F56219FEB91FB2CDD35F794FE" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_FD4F914A6B33D95F792A2CDD35F72A50" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LoansPayableMember" xlink:label="loc_us-gaap_LoansPayableMember_F343A0BA83A21BE8792F2CDD35F80982" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_FD4F914A6B33D95F792A2CDD35F72A50" xlink:to="loc_us-gaap_LoansPayableMember_F343A0BA83A21BE8792F2CDD35F80982" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_76A8379C5A13A447ED552CDD35F8C6A3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:to="loc_us-gaap_DebtInstrumentAxis_76A8379C5A13A447ED552CDD35F8C6A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_6622006F60F5EE77B9C02CDD35F88C06" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_76A8379C5A13A447ED552CDD35F8C6A3" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_6622006F60F5EE77B9C02CDD35F88C06" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PromissoryNoteMember" xlink:label="loc_abus_PromissoryNoteMember_B87AD50AE1DE3A17BEF12CDD35F81B36" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_6622006F60F5EE77B9C02CDD35F88C06" xlink:to="loc_abus_PromissoryNoteMember_B87AD50AE1DE3A17BEF12CDD35F81B36" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableRateAxis" xlink:label="loc_us-gaap_VariableRateAxis_034DFE7280B17E253E252CDD35F63F31" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:to="loc_us-gaap_VariableRateAxis_034DFE7280B17E253E252CDD35F63F31" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_VariableRateDomain" xlink:label="loc_us-gaap_VariableRateDomain_C8F44D30583AB2B7047B2CDD35F71C60" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_034DFE7280B17E253E252CDD35F63F31" xlink:to="loc_us-gaap_VariableRateDomain_C8F44D30583AB2B7047B2CDD35F71C60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_DE08DD5C6802C52047A52CDD35F7C186" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_C8F44D30583AB2B7047B2CDD35F71C60" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_DE08DD5C6802C52047A52CDD35F7C186" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_4DEB90F0788C5039C4B42CDD35F515B3" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:to="loc_srt_CounterpartyNameAxis_4DEB90F0788C5039C4B42CDD35F515B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_70F5B26A9611A071E1BC2CDD35F6BCCC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_4DEB90F0788C5039C4B42CDD35F515B3" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_70F5B26A9611A071E1BC2CDD35F6BCCC" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_WellsFargoMember" xlink:label="loc_abus_WellsFargoMember_B55C42AB685ED470E8C62CDD35F6DBFD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_70F5B26A9611A071E1BC2CDD35F6BCCC" xlink:to="loc_abus_WellsFargoMember_B55C42AB685ED470E8C62CDD35F6DBFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_662A9ED12EFB04143DD32CDD35F5249C" xlink:to="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentFaceAmount" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_311E1A3E90F4F7800AB62CDD35F9AE79" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_311E1A3E90F4F7800AB62CDD35F9AE79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_EAC22EB3B505231E2CF12CDD35F93148" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_EAC22EB3B505231E2CF12CDD35F93148" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestrictedInvestmentsNoncurrent" xlink:label="loc_us-gaap_RestrictedInvestmentsNoncurrent_9082B1E00BABD82A01D22CDD35F910CE" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:to="loc_us-gaap_RestrictedInvestmentsNoncurrent_9082B1E00BABD82A01D22CDD35F910CE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RestrictedInvestmentTerm" xlink:label="loc_abus_RestrictedInvestmentTerm_8B983F155C0184FF22022CDD35FADAE9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:to="loc_abus_RestrictedInvestmentTerm_8B983F155C0184FF22022CDD35FADAE9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShortTermInvestments" xlink:label="loc_us-gaap_ShortTermInvestments_1857DDCD35585EDF551F2D0C6DFAA084" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_56C610AF2D95E17FAB6F2CDD35F96D2B" xlink:to="loc_us-gaap_ShortTermInvestments_1857DDCD35585EDF551F2D0C6DFAA084" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/NatureOfBusinessAndFutureOperations" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5A977F26BB4A216CA3A02C558623C4FF" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NatureOfOperations" xlink:label="loc_us-gaap_NatureOfOperations_309B2CD4E478EFF95C302C5586236FF9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_5A977F26BB4A216CA3A02C558623C4FF" xlink:to="loc_us-gaap_NatureOfOperations_309B2CD4E478EFF95C302C5586236FF9" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/PropertyAndEquipment" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_77373CFF0F2895BDA84AF28A7C515807" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_2621590B24732B300C89F28A7C514143" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_77373CFF0F2895BDA84AF28A7C515807" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_2621590B24732B300C89F28A7C514143" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/PropertyAndEquipmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_E92442FD7EE4D1719BA72CDD363BF16A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_B0ED2D566CCD974F86BF2CDD363B6909" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_E92442FD7EE4D1719BA72CDD363BF16A" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_B0ED2D566CCD974F86BF2CDD363B6909" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_95C5CFC006A6B04B8AB62CDD363CA94A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_B0ED2D566CCD974F86BF2CDD363B6909" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_95C5CFC006A6B04B8AB62CDD363CA94A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_95C5CFC006A6B04B8AB62CDD363CA94A" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_LaboratoryEquipmentMember" xlink:label="loc_abus_LaboratoryEquipmentMember_0CB17DECE49BB0F3FB602CDD363CDA8D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:to="loc_abus_LaboratoryEquipmentMember_0CB17DECE49BB0F3FB602CDD363CDA8D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LeaseholdImprovementsMember" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_6E17012082E5E1C63EE52CDD363D6EB6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_6E17012082E5E1C63EE52CDD363D6EB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComputerEquipmentMember" xlink:label="loc_us-gaap_ComputerEquipmentMember_5F33286633BC8A508EF72CDD363DD566" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:to="loc_us-gaap_ComputerEquipmentMember_5F33286633BC8A508EF72CDD363DD566" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FurnitureAndFixturesMember" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_0648FEAD2D761EAC816E2CDD363DA2B0" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_AE9F1A30260A670A98972CDD363CFF07" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_0648FEAD2D761EAC816E2CDD363DA2B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_D5FB5AD7952DD1D623B12CDD363D054D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_B0ED2D566CCD974F86BF2CDD363B6909" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_D5FB5AD7952DD1D623B12CDD363D054D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_4872CEBE330645FBBA602CDD363DE106" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_D5FB5AD7952DD1D623B12CDD363D054D" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_4872CEBE330645FBBA602CDD363DE106" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_82C3AB2B781EB8C061E02CDD363ECCC6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_D5FB5AD7952DD1D623B12CDD363D054D" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_82C3AB2B781EB8C061E02CDD363ECCC6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_49A9F7EA3CD9DCDA98AA2CDD363E8D41" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_D5FB5AD7952DD1D623B12CDD363D054D" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_49A9F7EA3CD9DCDA98AA2CDD363E8D41" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/PropertyAndEquipmentNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_96778CDB1D0B890CEC362CDD3637DE59" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_96778CDB1D0B890CEC362CDD3637DE59" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D56FAF05B6AE7078982F2CEF3B447EF3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D56FAF05B6AE7078982F2CEF3B447EF3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_4BF6A4BCFF87F0C7A4912CF00963E99F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D56FAF05B6AE7078982F2CEF3B447EF3" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_4BF6A4BCFF87F0C7A4912CF00963E99F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_SubleaseBurnabyFacilityMember" xlink:label="loc_abus_SubleaseBurnabyFacilityMember_284378AD4CF8E5A4E3E72CEF823DE433" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_4BF6A4BCFF87F0C7A4912CF00963E99F" xlink:to="loc_abus_SubleaseBurnabyFacilityMember_284378AD4CF8E5A4E3E72CEF823DE433" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_F66B0537EAA228215B9F2CF2915D937F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_F66B0537EAA228215B9F2CF2915D937F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_1405F868F1D2BF4357302CF2915F9F1E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_F66B0537EAA228215B9F2CF2915D937F" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_1405F868F1D2BF4357302CF2915F9F1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FacilityClosingMember" xlink:label="loc_us-gaap_FacilityClosingMember_AD912A46322B956A81C52CF2B61F436F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_1405F868F1D2BF4357302CF2915F9F1E" xlink:to="loc_us-gaap_FacilityClosingMember_AD912A46322B956A81C52CF2B61F436F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_20B6F5A106DA8B7C94822CF1C898AB42" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_20B6F5A106DA8B7C94822CF1C898AB42" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_57BD18DEB553709929982CF50A2B37BB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_20B6F5A106DA8B7C94822CF1C898AB42" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_57BD18DEB553709929982CF50A2B37BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisposalGroupDisposedOfByMeansOtherThanSaleNotDiscontinuedOperationsMember" xlink:label="loc_us-gaap_DisposalGroupDisposedOfByMeansOtherThanSaleNotDiscontinuedOperationsMember_3B4A264181C637E613852CF4BF96C078" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_57BD18DEB553709929982CF50A2B37BB" xlink:to="loc_us-gaap_DisposalGroupDisposedOfByMeansOtherThanSaleNotDiscontinuedOperationsMember_3B4A264181C637E613852CF4BF96C078" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_547826015AE968FDA0742CF5EF4FC9B7" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_547826015AE968FDA0742CF5EF4FC9B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_D8721CE34896C8FA91502CF5EF5A1AEF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_547826015AE968FDA0742CF5EF4FC9B7" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_D8721CE34896C8FA91502CF5EF5A1AEF" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_30D76E671584D14355B22CF60E014AB2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D8721CE34896C8FA91502CF5EF5A1AEF" xlink:to="loc_abus_GenevantSciencesCorporationMember_30D76E671584D14355B22CF60E014AB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_27885405C5314FFA1F8D2CEF22786ED5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5EAA24AECD8E0F3C2CD02CEF2274645C" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_27885405C5314FFA1F8D2CEF22786ED5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_B86B598B5C11AFAF3F482CEDE047D3A2" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_27885405C5314FFA1F8D2CEF22786ED5" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_B86B598B5C11AFAF3F482CEDE047D3A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_A6FB3E86E6297678E08D2CEDE088BDEA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_27885405C5314FFA1F8D2CEF22786ED5" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_A6FB3E86E6297678E08D2CEDE088BDEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_43D2E121A435347AE5C22CEDE0D1FB5E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_27885405C5314FFA1F8D2CEF22786ED5" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_43D2E121A435347AE5C22CEDE0D1FB5E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/PropertyAndEquipmentTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAbstract" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_54C54D05578255ED3EACAD3F98FA6EFB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_19255F3D3C88E4FA3197AD3F98FBD005" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_54C54D05578255ED3EACAD3F98FA6EFB" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_19255F3D3C88E4FA3197AD3F98FBD005" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/RefundableInvestmentTaxCredits" xlink:type="extended">
    <link:loc xlink:href="abus-20181231.xsd#abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract" xlink:label="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract_17B7487CE1D0BFD88660F287D2E99A5B" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RefundableInvestmentTaxCreditsTextBlock" xlink:label="loc_abus_RefundableInvestmentTaxCreditsTextBlock_DDA1BD133D49652C2616F287D2E9C7AB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract_17B7487CE1D0BFD88660F287D2E99A5B" xlink:to="loc_abus_RefundableInvestmentTaxCreditsTextBlock_DDA1BD133D49652C2616F287D2E9C7AB" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/RefundableInvestmentTaxCreditsDetails" xlink:type="extended">
    <link:loc xlink:href="abus-20181231.xsd#abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract" xlink:label="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract_845EF89364E65BB99A66402213BF094C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentTaxCredit" xlink:label="loc_us-gaap_InvestmentTaxCredit_D7F0C4A6E0B0403B1889402213BF99B6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsAbstract_845EF89364E65BB99A66402213BF094C" xlink:to="loc_us-gaap_InvestmentTaxCredit_D7F0C4A6E0B0403B1889402213BF99B6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/RelatedPartyTransactions" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_27EE86E292DB1F9827F14022149A03B9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionsDisclosureTextBlock" xlink:label="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_B59D07B2F2C9EEFC91E54022149AB2A3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_27EE86E292DB1F9827F14022149A03B9" xlink:to="loc_us-gaap_RelatedPartyTransactionsDisclosureTextBlock_B59D07B2F2C9EEFC91E54022149AB2A3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/RelatedPartyTransactionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionsAbstract" xlink:label="loc_us-gaap_RelatedPartyTransactionsAbstract_28C1229BA69DA78957204B455A011302" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable" xlink:label="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsAbstract_28C1229BA69DA78957204B455A011302" xlink:to="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_DA0AA35E56699B2D18094B455A019302" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:to="loc_srt_CounterpartyNameAxis_DA0AA35E56699B2D18094B455A019302" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C8A9DCBD7B3B5AE797D34B455A01579C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_DA0AA35E56699B2D18094B455A019302" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C8A9DCBD7B3B5AE797D34B455A01579C" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoivantSciencesLtdMember" xlink:label="loc_abus_RoivantSciencesLtdMember_B9787192D5580D90765E4B455A015C02" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C8A9DCBD7B3B5AE797D34B455A01579C" xlink:to="loc_abus_RoivantSciencesLtdMember_B9787192D5580D90765E4B455A015C02" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GenevantSciencesCorporationMember" xlink:label="loc_abus_GenevantSciencesCorporationMember_14B10718B048CA8190B04B455A014117" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C8A9DCBD7B3B5AE797D34B455A01579C" xlink:to="loc_abus_GenevantSciencesCorporationMember_14B10718B048CA8190B04B455A014117" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1B130A9B9C2D5375CE84B455A01848A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1B130A9B9C2D5375CE84B455A01848A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_F8E7D4C23C9E44DC50524B455A01FBF3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_E1B130A9B9C2D5375CE84B455A01848A" xlink:to="loc_us-gaap_RelatedPartyDomain_F8E7D4C23C9E44DC50524B455A01FBF3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CoVenturerMember" xlink:label="loc_us-gaap_CoVenturerMember_E407D2D8C15C1A7864614B455A01E8E9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_F8E7D4C23C9E44DC50524B455A01FBF3" xlink:to="loc_us-gaap_CoVenturerMember_E407D2D8C15C1A7864614B455A01E8E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvesteeMember" xlink:label="loc_us-gaap_EquityMethodInvesteeMember_FDC5E4CB13514B082C854B455A01BC15" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_F8E7D4C23C9E44DC50524B455A01FBF3" xlink:to="loc_us-gaap_EquityMethodInvesteeMember_FDC5E4CB13514B082C854B455A01BC15" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_9C64F9C70623720254514B455A01307C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_9C64F9C70623720254514B455A01307C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_8FFD0C1C806DED40C7704B455A01B595" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_9C64F9C70623720254514B455A01307C" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_8FFD0C1C806DED40C7704B455A01B595" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ResearchAndDevelopmentServicesMember" xlink:label="loc_abus_ResearchAndDevelopmentServicesMember_A33AB51378BA3214CE1A4B455A01CC69" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_8FFD0C1C806DED40C7704B455A01B595" xlink:to="loc_abus_ResearchAndDevelopmentServicesMember_A33AB51378BA3214CE1A4B455A01CC69" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_AdministrativeAndTransitionalServicesMember" xlink:label="loc_abus_AdministrativeAndTransitionalServicesMember_D84E88E08979D55941CE4B455A01E0B3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_8FFD0C1C806DED40C7704B455A01B595" xlink:to="loc_abus_AdministrativeAndTransitionalServicesMember_D84E88E08979D55941CE4B455A01E0B3" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_SubleaseBurnabyFacilityMember" xlink:label="loc_abus_SubleaseBurnabyFacilityMember_A3880B71AB0CDB3129BC4B455A011325" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_8FFD0C1C806DED40C7704B455A01B595" xlink:to="loc_abus_SubleaseBurnabyFacilityMember_A3880B71AB0CDB3129BC4B455A011325" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionLineItems" xlink:label="loc_us-gaap_RelatedPartyTransactionLineItems_77F56F00A098A987B6234B455A01B026" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRelatedPartyTransactionsByRelatedPartyTable_D9D3718F14CADFABC4664B455A0174CD" xlink:to="loc_us-gaap_RelatedPartyTransactionLineItems_77F56F00A098A987B6234B455A01B026" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty" xlink:label="loc_us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty_6912DD77E79485ABA0024B455A012627" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_77F56F00A098A987B6234B455A01B026" xlink:to="loc_us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty_6912DD77E79485ABA0024B455A012627" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NetRentableAreaSublease" xlink:label="loc_abus_NetRentableAreaSublease_3F4C897916F3B997E7494B455A013B03" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_77F56F00A098A987B6234B455A01B026" xlink:to="loc_abus_NetRentableAreaSublease_3F4C897916F3B997E7494B455A013B03" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromRelatedParties" xlink:label="loc_us-gaap_RevenueFromRelatedParties_A96F76947AA2B2438F654B455A01CB7D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionLineItems_77F56F00A098A987B6234B455A01B026" xlink:to="loc_us-gaap_RevenueFromRelatedParties_A96F76947AA2B2438F654B455A01CB7D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ShareholdersEquity" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_BC43A31372A0570D77D04018679EAAEB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_3D08A8512CF6041CBBF94018679E642D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_BC43A31372A0570D77D04018679EAAEB" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_3D08A8512CF6041CBBF94018679E642D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/ShareholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityAbstract" xlink:label="loc_us-gaap_EquityAbstract_1C6824B2C2724E1BBE7F401A44D57448" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_1C6824B2C2724E1BBE7F401A44D57448" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_DB77BE23E0BB1C17FA7A401A44D6276F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:to="loc_us-gaap_AwardTypeAxis_DB77BE23E0BB1C17FA7A401A44D6276F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_676A0D9C3019BC352071401A44D6F79B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_DB77BE23E0BB1C17FA7A401A44D6276F" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_676A0D9C3019BC352071401A44D6F79B" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_2FCAFDF615B596AF4DE8401A44D6FAEA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_676A0D9C3019BC352071401A44D6F79B" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_2FCAFDF615B596AF4DE8401A44D6FAEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaap_StatementClassOfStockAxis_6A88874E78B4E5D8C911401A44D78E3F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:to="loc_us-gaap_StatementClassOfStockAxis_6A88874E78B4E5D8C911401A44D78E3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaap_ClassOfStockDomain_05FD97A9D233F09DD7CD401A44D729AD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_6A88874E78B4E5D8C911401A44D78E3F" xlink:to="loc_us-gaap_ClassOfStockDomain_05FD97A9D233F09DD7CD401A44D729AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_D3A5FE05BA9078B374EC401A44D7C7ED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_05FD97A9D233F09DD7CD401A44D729AD" xlink:to="loc_us-gaap_CommonStockMember_D3A5FE05BA9078B374EC401A44D7C7ED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConvertiblePreferredStockMember" xlink:label="loc_us-gaap_ConvertiblePreferredStockMember_321238CDC342FFAB39AA401A44D7F9CB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_05FD97A9D233F09DD7CD401A44D729AD" xlink:to="loc_us-gaap_ConvertiblePreferredStockMember_321238CDC342FFAB39AA401A44D7F9CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_94FEED36B0EDEE1A775D401A44D8CADF" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_94FEED36B0EDEE1A775D401A44D8CADF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_D8A4306DDA9D3FE35CBA401A44D85099" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_94FEED36B0EDEE1A775D401A44D8CADF" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_D8A4306DDA9D3FE35CBA401A44D85099" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OpenMarketSaleAgreementMember" xlink:label="loc_abus_OpenMarketSaleAgreementMember_D4552FA926674F6992A8401A44D81A05" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_D8A4306DDA9D3FE35CBA401A44D85099" xlink:to="loc_abus_OpenMarketSaleAgreementMember_D4552FA926674F6992A8401A44D81A05" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_B8E02F9D400225E23631401A44D8B700" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:to="loc_srt_CounterpartyNameAxis_B8E02F9D400225E23631401A44D8B700" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8DE3F84D788B9F0A0978401A44D83174" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_B8E02F9D400225E23631401A44D8B700" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8DE3F84D788B9F0A0978401A44D83174" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_JefferiesLLCMember" xlink:label="loc_abus_JefferiesLLCMember_B589A1504C8F6265C150401A44D91293" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8DE3F84D788B9F0A0978401A44D83174" xlink:to="loc_abus_JefferiesLLCMember_B589A1504C8F6265C150401A44D91293" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RoivantSciencesLtdMember" xlink:label="loc_abus_RoivantSciencesLtdMember_ECBCDF16E85B02002E70401A44D916B3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_8DE3F84D788B9F0A0978401A44D83174" xlink:to="loc_abus_RoivantSciencesLtdMember_ECBCDF16E85B02002E70401A44D916B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfStockLineItems" xlink:label="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_71E921A8569C95A9644F401A44D56BBD" xlink:to="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueStockOptionsMeasurementInput" xlink:label="loc_abus_FairValueStockOptionsMeasurementInput_0BE112D53BA53477DFB3401A44D9BDB5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_FairValueStockOptionsMeasurementInput_0BE112D53BA53477DFB3401A44D9BDB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_D94EA55238C1FD637AE0401A44DA7EB1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_D94EA55238C1FD637AE0401A44DA7EB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockSharesSubscriptions" xlink:label="loc_us-gaap_CommonStockSharesSubscriptions_561C8109872EF25D4965401A44DA1679" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_CommonStockSharesSubscriptions_561C8109872EF25D4965401A44DA1679" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_214A7558770F81490E67401A44DA0A60" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_214A7558770F81490E67401A44DA0A60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_DFC219A41D0D2C41D8FE401A44DA793A" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueNewIssues_DFC219A41D0D2C41D8FE401A44DA793A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_45971A34219844185C58401A44DA33CE" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_45971A34219844185C58401A44DA33CE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PremiumonClosingStockPrice" xlink:label="loc_abus_PremiumonClosingStockPrice_1DF4FB28BF681967DDB5401A44DA80E6" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_PremiumonClosingStockPrice_1DF4FB28BF681967DDB5401A44DA80E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharePrice" xlink:label="loc_us-gaap_SharePrice_9476DED22159569EACE2401A44DBEA7D" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_SharePrice_9476DED22159569EACE2401A44DBEA7D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockDividendRatePercentage" xlink:label="loc_us-gaap_PreferredStockDividendRatePercentage_341475034CA42CF100FD401A44DBE21B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_PreferredStockDividendRatePercentage_341475034CA42CF100FD401A44DBE21B" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion" xlink:label="loc_abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion_176465488CA9C3EC4312401A44DB69C1" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_NoncontrollingInterestOwnershipPercentageByNoncontrollingOwnersAfterConversion_176465488CA9C3EC4312401A44DB69C1" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NoncontrollingInterestInvestmentCommitmentPeriod" xlink:label="loc_abus_NoncontrollingInterestInvestmentCommitmentPeriod_60367E835BA6925B0573401A44DB5FC9" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_NoncontrollingInterestInvestmentCommitmentPeriod_60367E835BA6925B0573401A44DB5FC9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners" xlink:label="loc_abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners_417ACF0C13D9A54B436D401A44DB9506" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_NoncontrollingInterestMaximumOwnershipPercentagebyNoncontrollingOwners_417ACF0C13D9A54B436D401A44DB9506" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_07ECC50FEE3CF63B76CB401A44DB21DB" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfConvertiblePreferredStock_07ECC50FEE3CF63B76CB401A44DB21DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_07BA925379CF9CA82B1D401A44DC62DF" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_07BA925379CF9CA82B1D401A44DC62DF" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_WarrantsExercised" xlink:label="loc_abus_WarrantsExercised_C1E916C4EB0D2A273DDD401A44DC1016" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_WarrantsExercised_C1E916C4EB0D2A273DDD401A44DC1016" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ProceedsFromWarrantExercises" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_39B7A7C7707D872B46FB401A44DCB289" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_39B7A7C7707D872B46FB401A44DCB289" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ClassofWarrantorRightExpired" xlink:label="loc_abus_ClassofWarrantorRightExpired_9046D6E75E8CA7C0CB8E401A44DCAC6F" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_73EF4365C0D9D4B57886401A44D9AA75" xlink:to="loc_abus_ClassofWarrantorRightExpired_9046D6E75E8CA7C0CB8E401A44DCAC6F" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_633A4E93238E7E2076DC2C8568BD8F83" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_AF6146A0177437821BE32C8568BD921D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_633A4E93238E7E2076DC2C8568BD8F83" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_AF6146A0177437821BE32C8568BD921D" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesComputationOfBasicAndDilutedNetIncomeLossPerCommonShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_EF2C20B8C10175C43372402215E2E29E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_00E0B08C0124D7CBFB25402215E23602" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_EF2C20B8C10175C43372402215E2E29E" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_00E0B08C0124D7CBFB25402215E23602" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementClassOfStockAxis" xlink:label="loc_us-gaap_StatementClassOfStockAxis_E6C787FF986D9562371B402215E25632" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_00E0B08C0124D7CBFB25402215E23602" xlink:to="loc_us-gaap_StatementClassOfStockAxis_E6C787FF986D9562371B402215E25632" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ClassOfStockDomain" xlink:label="loc_us-gaap_ClassOfStockDomain_D34FA2BA53A41E87D4B8402215E229BB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementClassOfStockAxis_E6C787FF986D9562371B402215E25632" xlink:to="loc_us-gaap_ClassOfStockDomain_D34FA2BA53A41E87D4B8402215E229BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_5D1A1D4D23807F94994E402215E28BB0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_D34FA2BA53A41E87D4B8402215E229BB" xlink:to="loc_us-gaap_CommonStockMember_5D1A1D4D23807F94994E402215E28BB0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="loc_us-gaap_PreferredStockMember_96FEFA2D82740F48AC0F402215E20DBA" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockDomain_D34FA2BA53A41E87D4B8402215E229BB" xlink:to="loc_us-gaap_PreferredStockMember_96FEFA2D82740F48AC0F402215E20DBA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicLineItems" xlink:label="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEarningsPerShareBasicByCommonClassTable_00E0B08C0124D7CBFB25402215E23602" xlink:to="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockDividendsAndOtherAdjustments" xlink:label="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_7A48FD26922F53903DB7402215E21377" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:to="loc_us-gaap_PreferredStockDividendsAndOtherAdjustments_7A48FD26922F53903DB7402215E21377" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic" xlink:label="loc_us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic_FCF7F2436A3A059CB7E3402215E208E3" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:to="loc_us-gaap_UndistributedEarningsLossAvailableToCommonShareholdersBasic_FCF7F2436A3A059CB7E3402215E208E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2D27D4213AF8971300BB402215E2A3B1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2D27D4213AF8971300BB402215E2A3B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted" xlink:label="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_81124DB25233D0700245402215E21863" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:to="loc_us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted_81124DB25233D0700245402215E21863" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerShareBasicAndDiluted" xlink:label="loc_us-gaap_EarningsPerShareBasicAndDiluted_1B2F1A03F95DC8D22A19402215E25665" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EarningsPerShareBasicLineItems_D9F66F6EEB7186F26AF2402215E28F95" xlink:to="loc_us-gaap_EarningsPerShareBasicAndDiluted_1B2F1A03F95DC8D22A19402215E25665" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesEstimatedUsefulLivesOfPropertyAndEquipmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_031870A2A34FA517C2D8402215F106E1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_2AA03FFE4CEC2974D5F2402215F1E7FA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_031870A2A34FA517C2D8402215F106E1" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_2AA03FFE4CEC2974D5F2402215F1E7FA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_453D560C3FD8EC5ECAAA402215F13F21" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_2AA03FFE4CEC2974D5F2402215F1E7FA" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_453D560C3FD8EC5ECAAA402215F13F21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F8F4AB3C09C8F168D0B2402215F1C8E3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_453D560C3FD8EC5ECAAA402215F13F21" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F8F4AB3C09C8F168D0B2402215F1C8E3" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_LaboratoryEquipmentMember" xlink:label="loc_abus_LaboratoryEquipmentMember_D8E77E51E2A91836EF92402215F151C8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F8F4AB3C09C8F168D0B2402215F1C8E3" xlink:to="loc_abus_LaboratoryEquipmentMember_D8E77E51E2A91836EF92402215F151C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ComputerEquipmentMember" xlink:label="loc_us-gaap_ComputerEquipmentMember_3D4EFBDD2177079CCFFD402215F1542B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F8F4AB3C09C8F168D0B2402215F1C8E3" xlink:to="loc_us-gaap_ComputerEquipmentMember_3D4EFBDD2177079CCFFD402215F1542B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FurnitureAndFixturesMember" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_DFF6C67889F68F271BC6402215F13703" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_F8F4AB3C09C8F168D0B2402215F1C8E3" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_DFF6C67889F68F271BC6402215F13703" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_5D2CB93D3F1765E368D4402215F10AE2" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_2AA03FFE4CEC2974D5F2402215F1E7FA" xlink:to="loc_srt_RangeAxis_5D2CB93D3F1765E368D4402215F10AE2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_E85CEE1CABFF5FE52AF6402215F149C5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_5D2CB93D3F1765E368D4402215F10AE2" xlink:to="loc_srt_RangeMember_E85CEE1CABFF5FE52AF6402215F149C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_68F8E5E6A31DA4E1394E402215F12D81" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_E85CEE1CABFF5FE52AF6402215F149C5" xlink:to="loc_srt_MinimumMember_68F8E5E6A31DA4E1394E402215F12D81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2018/elts/srt-2018-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_1BF4BA4D03C86E1EBC0F402215F1C044" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_E85CEE1CABFF5FE52AF6402215F149C5" xlink:to="loc_srt_MaximumMember_1BF4BA4D03C86E1EBC0F402215F1C044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentLineItems" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_70DDDB426C996AA95340402215F1F1CD" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_2AA03FFE4CEC2974D5F2402215F1E7FA" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_70DDDB426C996AA95340402215F1F1CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_113759D75A68959A6988402215F17ABF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_70DDDB426C996AA95340402215F1F1CD" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_113759D75A68959A6988402215F17ABF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_51FE12DBDA7DAC086375402216119161" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_51FE12DBDA7DAC086375402216119161" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_9C1A1E8725EC34E837BE40221611618C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_9C1A1E8725EC34E837BE40221611618C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5632112BBF7356C84B91402216118202" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_9C1A1E8725EC34E837BE40221611618C" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5632112BBF7356C84B91402216118202" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PADCo.Member" xlink:label="loc_abus_PADCo.Member_B99D95CC427FAF5CA402402216118738" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_5632112BBF7356C84B91402216118202" xlink:to="loc_abus_PADCo.Member_B99D95CC427FAF5CA402402216118738" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_AA6951B24EA6C6E6F023402216116CBC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_AA6951B24EA6C6E6F023402216116CBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C9BAA6ADF954E05AD4BB40221611C0DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_AA6951B24EA6C6E6F023402216116CBC" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C9BAA6ADF954E05AD4BB40221611C0DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_40BBA34161C643E80ED940221611AA38" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C9BAA6ADF954E05AD4BB40221611C0DD" xlink:to="loc_us-gaap_EmployeeStockOptionMember_40BBA34161C643E80ED940221611AA38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="loc_us-gaap_PreferredStockMember_EFF9439B6B7DECFFFC10402216115062" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_C9BAA6ADF954E05AD4BB40221611C0DD" xlink:to="loc_us-gaap_PreferredStockMember_EFF9439B6B7DECFFFC10402216115062" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_90488657D3135D0EE50540221611B68C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:to="loc_dei_LegalEntityAxis_90488657D3135D0EE50540221611B68C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2018/dei-2018-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_9AFB95E559FB497E919B4022161106C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_LegalEntityAxis_90488657D3135D0EE50540221611B68C" xlink:to="loc_dei_EntityDomain_9AFB95E559FB497E919B4022161106C0" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_MonsantoMember" xlink:label="loc_abus_MonsantoMember_C1A0A88E22BC9C6D30994022161198ED" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_EntityDomain_9AFB95E559FB497E919B4022161106C0" xlink:to="loc_abus_MonsantoMember_C1A0A88E22BC9C6D30994022161198ED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_2688C0A35F43F32BC9AD40221611DD3C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_2688C0A35F43F32BC9AD40221611DD3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_A48993B745805D68DC5D40221611C2F9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_2688C0A35F43F32BC9AD40221611DD3C" xlink:to="loc_us-gaap_EquityComponentDomain_A48993B745805D68DC5D40221611C2F9" xlink:type="arc" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_A48993B745805D68DC5D40221611C2F9" xlink:to="loc_us-gaap_PreferredStockMember_EFF9439B6B7DECFFFC10402216115062" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_90C9E1738F57C2060F5740221611BA74" xlink:to="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements" xlink:label="loc_abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements_3817FA0A16690A6E498040221611E6D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_abus_WhollyOwnedSubsidiariesIncludedinFinancialStatements_3817FA0A16690A6E498040221611E6D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired" xlink:label="loc_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_9E321195DA08AA376C184022161140C6" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_us-gaap_BusinessAcquisitionPercentageOfVotingInterestsAcquired_9E321195DA08AA376C184022161140C6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_13DE0B8AF9CB2C28C074402216115AF5" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_13DE0B8AF9CB2C28C074402216115AF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_InvestmentInterestRate" xlink:label="loc_invest_InvestmentInterestRate_3F159815893604DF9330402216114B34" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_invest_InvestmentInterestRate_3F159815893604DF9330402216114B34" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_BF643EA6FA2BFDC27BDC40221611B770" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_BF643EA6FA2BFDC27BDC40221611B770" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NumberofLeases" xlink:label="loc_abus_NumberofLeases_AB8BA74A6BEC3D26B5754087A6D36507" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_A392C032F207615A24F140221611F5C2" xlink:to="loc_abus_NumberofLeases_AB8BA74A6BEC3D26B5754087A6D36507" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_CEE847303CB67B41392A2C8568AE9D4F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_CEE847303CB67B41392A2C8568AE9D4F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConsolidationPolicyTextBlock" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_CABE9162D5A779FB809B2C928FB71024" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_CABE9162D5A779FB809B2C928FB71024" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_3DBF701A9FB9657F45532C8568AE6594" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_3DBF701A9FB9657F45532C8568AE6594" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="loc_us-gaap_UseOfEstimates_8680B34C513864B165BB2C8568AEAF62" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_UseOfEstimates_8680B34C513864B165BB2C8568AEAF62" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CashAndCashEquivalentsPolicyTextBlock" xlink:label="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_818CD15DCD5A888232D82C8568AF4F18" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_CashAndCashEquivalentsPolicyTextBlock_818CD15DCD5A888232D82C8568AF4F18" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_InvestmentPolicyTextBlock" xlink:label="loc_us-gaap_InvestmentPolicyTextBlock_FFCF0674283E832C368B2C8568AFDEFE" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_InvestmentPolicyTextBlock_FFCF0674283E832C368B2C8568AFDEFE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EquityMethodInvestmentsPolicy" xlink:label="loc_us-gaap_EquityMethodInvestmentsPolicy_88EC3D68433CAB762C3D2C91083FE5B4" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_EquityMethodInvestmentsPolicy_88EC3D68433CAB762C3D2C91083FE5B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_3DD22C149CB179090C7F2C8568AF783E" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_3DD22C149CB179090C7F2C8568AF783E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock" xlink:label="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock_65C0076B654AA97633C42C8568AF171B" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_ImpairmentOrDisposalOfLongLivedAssetsPolicyTextBlock_65C0076B654AA97633C42C8568AF171B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_99F1BD53A27251D5069F2C8568B0FE69" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsPolicyTextBlock_99F1BD53A27251D5069F2C8568B0FE69" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_3F625EA1B613086423DE2C8568B03462" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_3F625EA1B613086423DE2C8568B03462" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_69014123ABACE6DA28D72C8568B049D7" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_69014123ABACE6DA28D72C8568B049D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchDevelopmentAndComputerSoftwarePolicyTextBlock" xlink:label="loc_us-gaap_ResearchDevelopmentAndComputerSoftwarePolicyTextBlock_FF80C46F36656210EF882C8568B04485" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_ResearchDevelopmentAndComputerSoftwarePolicyTextBlock_FF80C46F36656210EF882C8568B04485" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_ECD672B70F92E7A527E82C8568B0CC60" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_ECD672B70F92E7A527E82C8568B0CC60" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsPolicyTextBlock" xlink:label="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsPolicyTextBlock_ED70E405BD003901E9C22C8568B1D2B4" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_abus_GovernmentGrantsAndRefundableInvestmentTaxCreditsPolicyTextBlock_ED70E405BD003901E9C22C8568B1D2B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeTaxPolicyTextBlock" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_1923EFAD7F1C0BDD36782C8568B1EC1A" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_1923EFAD7F1C0BDD36782C8568B1EC1A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_A6E0F86F5B64C98744AA2C8568B15945" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_A6E0F86F5B64C98744AA2C8568B15945" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ReplacementAwardsPolicyTextBlock" xlink:label="loc_abus_ReplacementAwardsPolicyTextBlock_5829257C92BE6AF6DF1F2C8568B1DD78" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_abus_ReplacementAwardsPolicyTextBlock_5829257C92BE6AF6DF1F2C8568B1DD78" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_WarrantsPolicyTextBlock" xlink:label="loc_abus_WarrantsPolicyTextBlock_ED9E748CBB82FC90857F2C8568B13E99" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_abus_WarrantsPolicyTextBlock_ED9E748CBB82FC90857F2C8568B13E99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy" xlink:label="loc_us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy_27812F6C9C4E43253A122C8568B187AC" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_StockholdersEquityNoteRedeemablePreferredStockIssuePolicy_27812F6C9C4E43253A122C8568B187AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_805559301EF998EB01A42C8568B2B7C6" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_805559301EF998EB01A42C8568B2B7C6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_80C1DDFE7037BF5775EC2C8568B26987" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_80C1DDFE7037BF5775EC2C8568B26987" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_4D45A7CF940104BBE7492C8568AF2F32" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_6DB21AF0383AAA729A242C8568AE2CBD" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_4D45A7CF940104BBE7492C8568AF2F32" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_513C6D626FD2567A95B32C85689D0E36" xlink:type="locator" />
    <link:loc xlink:href="abus-20181231.xsd#abus_PropertyPlantAndEquipmentEstimatedUsefulLivesTableTextBlock" xlink:label="loc_abus_PropertyPlantAndEquipmentEstimatedUsefulLivesTableTextBlock_D5BE0E76BF1C840DAE092C85689E8BCC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_513C6D626FD2567A95B32C85689D0E36" xlink:to="loc_abus_PropertyPlantAndEquipmentEstimatedUsefulLivesTableTextBlock_D5BE0E76BF1C840DAE092C85689E8BCC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_F9A2467269DCE35580D42C85689E3B23" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_513C6D626FD2567A95B32C85689D0E36" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_F9A2467269DCE35580D42C85689E3B23" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SiteConsolidation" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_AE612D722291227BFB7B2CDD360977CB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_B8AE98B7CA61D7F749102CDD3609B550" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_AE612D722291227BFB7B2CDD360977CB" xlink:to="loc_us-gaap_RestructuringAndRelatedActivitiesDisclosureTextBlock_B8AE98B7CA61D7F749102CDD3609B550" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SiteConsolidationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_156B8F88E91A83482A3B4022142D04F1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_9E44348415FA498B5AF14022142DBA31" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_156B8F88E91A83482A3B4022142D04F1" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_9E44348415FA498B5AF14022142DBA31" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_2BFADEFE4E0D8CED2C1F4022142DC0CB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_9E44348415FA498B5AF14022142DBA31" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_2BFADEFE4E0D8CED2C1F4022142DC0CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_2BFADEFE4E0D8CED2C1F4022142DC0CB" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_FacilityClosingMember" xlink:label="loc_us-gaap_FacilityClosingMember_DDE86BAE27945E5471D54022143DAB3A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:to="loc_us-gaap_FacilityClosingMember_DDE86BAE27945E5471D54022143DAB3A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeSeveranceMember" xlink:label="loc_us-gaap_EmployeeSeveranceMember_C33871881BC035E91DDA4022143D9A82" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:to="loc_us-gaap_EmployeeSeveranceMember_C33871881BC035E91DDA4022143D9A82" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeRelocationMember" xlink:label="loc_us-gaap_EmployeeRelocationMember_42D46E397AB2FDA584814022143D8C55" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:to="loc_us-gaap_EmployeeRelocationMember_42D46E397AB2FDA584814022143D8C55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ContractTerminationMember" xlink:label="loc_us-gaap_ContractTerminationMember_96AA980BD3364BC0A5324022143D2739" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_412DAE332E01CDB7AC014022143DEE05" xlink:to="loc_us-gaap_ContractTerminationMember_96AA980BD3364BC0A5324022143D2739" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_E8F805F24B0A592E30D44022143DD286" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_9E44348415FA498B5AF14022142DBA31" xlink:to="loc_us-gaap_RestructuringCostAndReserveLineItems_E8F805F24B0A592E30D44022143DD286" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent" xlink:label="loc_abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent_85ED3B274EA16E59F9A54022143DEB5F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E8F805F24B0A592E30D44022143DD286" xlink:to="loc_abus_RestructuringandRelatedCostExpectedNumberofPositionsEliminatedPercent_85ED3B274EA16E59F9A54022143DEB5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedCost1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_553278413B3C2EEA426A4022143D3C95" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E8F805F24B0A592E30D44022143DD286" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedCost1_553278413B3C2EEA426A4022143D3C95" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringChargesAbstract" xlink:label="loc_us-gaap_RestructuringChargesAbstract_FFA5747DF1BC5E6EF71E4022143D3D5E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E8F805F24B0A592E30D44022143DD286" xlink:to="loc_us-gaap_RestructuringChargesAbstract_FFA5747DF1BC5E6EF71E4022143D3D5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_CCE3166D75DF2BEC60FF4022143DD205" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringChargesAbstract_FFA5747DF1BC5E6EF71E4022143D3D5E" xlink:to="loc_us-gaap_RestructuringCharges_CCE3166D75DF2BEC60FF4022143DD205" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_DE99908F1BB10EF1267F4022143D7013" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringChargesAbstract_FFA5747DF1BC5E6EF71E4022143D3D5E" xlink:to="loc_us-gaap_PaymentsForRestructuring_DE99908F1BB10EF1267F4022143D7013" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringReservePeriodIncreaseDecrease" xlink:label="loc_us-gaap_RestructuringReservePeriodIncreaseDecrease_3CA1AD00FD481B900EFF4022143D7137" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/totalLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringChargesAbstract_FFA5747DF1BC5E6EF71E4022143D3D5E" xlink:to="loc_us-gaap_RestructuringReservePeriodIncreaseDecrease_3CA1AD00FD481B900EFF4022143D7137" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/SiteConsolidationTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_RestructuringAndRelatedActivitiesAbstract" xlink:label="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6FA1911E4654A88240422CDD36078D59" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_ED04AAA1977B491B0D012CDD3607DA0E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RestructuringAndRelatedActivitiesAbstract_6FA1911E4654A88240422CDD36078D59" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTextBlock_ED04AAA1977B491B0D012CDD3607DA0E" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensation" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2DEF5F2928AB73CB09583F2A4CF41778" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_1D80E4EE28BE53FE1C223F2A8EBBFD7A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_2DEF5F2928AB73CB09583F2A4CF41778" xlink:to="loc_us-gaap_DisclosureOfCompensationRelatedCostsShareBasedPaymentsTextBlock_1D80E4EE28BE53FE1C223F2A8EBBFD7A" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationLiabilityClassifiedOptionsOutstandingDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_BA02642E7229C73673353F0C9C8F58E5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_00B13AFFA3CA99C709263F0C9C8F7A8E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_BA02642E7229C73673353F0C9C8F58E5" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_00B13AFFA3CA99C709263F0C9C8F7A8E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_C5106E926570DA7978663F0C9C912260" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_00B13AFFA3CA99C709263F0C9C8F7A8E" xlink:to="loc_us-gaap_AwardTypeAxis_C5106E926570DA7978663F0C9C912260" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2E140C593293CC5673D73F0C9C92A398" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_C5106E926570DA7978663F0C9C912260" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2E140C593293CC5673D73F0C9C92A398" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_F411FECAA9CB56E5CCD43F0C9C921AD7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2E140C593293CC5673D73F0C9C92A398" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_F411FECAA9CB56E5CCD43F0C9C921AD7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_1144CAB708D6A0DD60803F0C9C8F6B38" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_00B13AFFA3CA99C709263F0C9C8F7A8E" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_1144CAB708D6A0DD60803F0C9C8F6B38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_1144CAB708D6A0DD60803F0C9C8F6B38" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range1Member" xlink:label="loc_abus_Range1Member_2B49DC28BBCD6508305B3F0C9C90E4F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range1Member_2B49DC28BBCD6508305B3F0C9C90E4F4" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range2Member" xlink:label="loc_abus_Range2Member_8D44D5451DFBF211F5733F0C9C903DDD" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range2Member_8D44D5451DFBF211F5733F0C9C903DDD" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range3Member" xlink:label="loc_abus_Range3Member_6D028B71411FB94A79363F0C9C9063DC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range3Member_6D028B71411FB94A79363F0C9C9063DC" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range4Member" xlink:label="loc_abus_Range4Member_2A0218974DD4FF7F55193F0C9C91CB6D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range4Member_2A0218974DD4FF7F55193F0C9C91CB6D" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range5Member" xlink:label="loc_abus_Range5Member_C144B61B41C72C4CB6513F0C9C91205F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range5Member_C144B61B41C72C4CB6513F0C9C91205F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range6Member" xlink:label="loc_abus_Range6Member_1F0B62D2C16F98A56B023F0C9C919DC9" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_Range6Member_1F0B62D2C16F98A56B023F0C9C919DC9" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TotalRangeMember" xlink:label="loc_abus_TotalRangeMember_D04FB44E74A257280A7C3F0C9C914249" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_A48B91DD66A7B3F680873F0C9C902A30" xlink:to="loc_abus_TotalRangeMember_D04FB44E74A257280A7C3F0C9C914249" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_00B13AFFA3CA99C709263F0C9C8F7A8E" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_AF991EF8736483E573FE3F0C9C92525F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_AF991EF8736483E573FE3F0C9C92525F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_582FB4A0D8B38366FEBB3F0C9C93A0D9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_582FB4A0D8B38366FEBB3F0C9C93A0D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions_9382A2ED9A247772E3BF3F0C9C933BF2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions_9382A2ED9A247772E3BF3F0C9C933BF2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_C7285A716345DAF0929D3F0C9C93CDFF" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_C7285A716345DAF0929D3F0C9C93CDFF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_98A0C584E0F8838482DD3F0C9C93E6C4" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_98A0C584E0F8838482DD3F0C9C93E6C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions_47BBEC7561A6D1A76C233F0C9C93A507" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions_47BBEC7561A6D1A76C233F0C9C93A507" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1" xlink:label="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1_6B9EEE0423330236BAD83F0C9C93D4DF" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_20F8DCA1411F3D2230363F0C9C927847" xlink:to="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1_6B9EEE0423330236BAD83F0C9C93D4DF" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_B26A3166AB99D5C673AC401C106DD6E6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_B26A3166AB99D5C673AC401C106DD6E6" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_E53F256599F8B8114234401C106DE8EF" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_E53F256599F8B8114234401C106DE8EF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_5E7CBE8B690A8AC0A6ED401C106D142A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_E53F256599F8B8114234401C106DE8EF" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_5E7CBE8B690A8AC0A6ED401C106D142A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_977704E3CAB5D1B06D7B401C106DB689" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_5E7CBE8B690A8AC0A6ED401C106D142A" xlink:to="loc_us-gaap_SubsequentEventMember_977704E3CAB5D1B06D7B401C106DB689" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_A583CA9AB20F05D1FED0401C106DA03D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:to="loc_us-gaap_PlanNameAxis_A583CA9AB20F05D1FED0401C106DA03D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_A583CA9AB20F05D1FED0401C106DA03D" xlink:to="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_A2016PlanMember" xlink:label="loc_abus_A2016PlanMember_127CDD1F2135A04D971C401C106D0AE0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_A2016PlanMember_127CDD1F2135A04D971C401C106D0AE0" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_A2011PlanMember" xlink:label="loc_abus_A2011PlanMember_E70486D827A539949565401C106D9A09" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_A2011PlanMember_E70486D827A539949565401C106D9A09" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_DesignatedPlansMember" xlink:label="loc_abus_DesignatedPlansMember_AAF809B24EE15EA2DC9E401C106D47A2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_DesignatedPlansMember_AAF809B24EE15EA2DC9E401C106D47A2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ArbutusPlansMember" xlink:label="loc_abus_ArbutusPlansMember_8B5C8CEE3E275221DEBF401C106D6678" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_ArbutusPlansMember_8B5C8CEE3E275221DEBF401C106D6678" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ProtivaOptionPlanMember" xlink:label="loc_abus_ProtivaOptionPlanMember_BB91735809ACA25EE253401C106D806F" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_ProtivaOptionPlanMember_BB91735809ACA25EE253401C106D806F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OnCoreOptionPlanMember" xlink:label="loc_abus_OnCoreOptionPlanMember_55B8F77ACA0BAEB41C90401C106DEF5A" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_01800D9314C32572BFE1401C106D62CE" xlink:to="loc_abus_OnCoreOptionPlanMember_55B8F77ACA0BAEB41C90401C106DEF5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_466BF1685CF0C2586E24401C106DB3F1" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:to="loc_us-gaap_AwardTypeAxis_466BF1685CF0C2586E24401C106DB3F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_466BF1685CF0C2586E24401C106DB3F1" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_5AC2943A4898CD7237F1401C106D2205" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_5AC2943A4898CD7237F1401C106D2205" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_RevisedNewCommonSharesMember" xlink:label="loc_abus_RevisedNewCommonSharesMember_307C61183474A137DBC4401C106DF502" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:to="loc_abus_RevisedNewCommonSharesMember_307C61183474A137DBC4401C106DF502" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ProtivaShareOptionsMember" xlink:label="loc_abus_ProtivaShareOptionsMember_9631EB31798CBBE6B454401C106D5666" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:to="loc_abus_ProtivaShareOptionsMember_9631EB31798CBBE6B454401C106D5666" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquivalentNumberOfCompanyCommonSharesMember" xlink:label="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_56C8E5DCFF7EB2308239401C106DA198" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:to="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_56C8E5DCFF7EB2308239401C106DA198" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ExpiredRepurchaseRightsOnSharesIssuedtoArbutusInc.Member" xlink:label="loc_abus_ExpiredRepurchaseRightsOnSharesIssuedtoArbutusInc.Member_93DF8AD1B4DE55CF5139401C106DC39B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_9AC5B7BCE945958664BE401C106D210C" xlink:to="loc_abus_ExpiredRepurchaseRightsOnSharesIssuedtoArbutusInc.Member_93DF8AD1B4DE55CF5139401C106DC39B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputTypeAxis" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_223F31F7D9104C8088B8401C106D4993" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_223F31F7D9104C8088B8401C106D4993" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_223F31F7D9104C8088B8401C106D4993" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_85B84DB59AD1B0D7D8BD401C106DB471" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_85B84DB59AD1B0D7D8BD401C106DB471" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputPriceVolatilityMember" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_9261257C24F9BDD5E8FA401C106D0921" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_9261257C24F9BDD5E8FA401C106D0921" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputExpectedDividendRateMember" xlink:label="loc_us-gaap_MeasurementInputExpectedDividendRateMember_58A7A4DD3F8A51A878C4401C106D3B1E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:to="loc_us-gaap_MeasurementInputExpectedDividendRateMember_58A7A4DD3F8A51A878C4401C106D3B1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_MeasurementInputExpectedTermMember" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_0408A327200DFCCB299F401C106D92A9" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_5BB5F80414686630B865401C106D72D7" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_0408A327200DFCCB299F401C106D92A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8AA42BC518566DA0C747401C106D6FEC" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_DB19A2161644E2BBDA23401C106D7882" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_DB19A2161644E2BBDA23401C106D7882" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_EC6978D3BA8B5227FC9A401C106DDFBC" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_EC6978D3BA8B5227FC9A401C106DDFBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_576491B1E18847B367B8401C106D6C75" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_576491B1E18847B367B8401C106D6C75" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_494BF60CB52099DBEB32401C106D30A4" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_494BF60CB52099DBEB32401C106D30A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_AC2479A2FDBC07183F7E401C106D3CF5" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_AC2479A2FDBC07183F7E401C106D3CF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_B506689B8F95946893F9401C106D2FF2" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_B506689B8F95946893F9401C106D2FF2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_NumberOfExecutiveOfficersGrantedOptionsWithNewAppointments" xlink:label="loc_abus_NumberOfExecutiveOfficersGrantedOptionsWithNewAppointments_9A3F44E241081DA380D7401C106D0A92" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_abus_NumberOfExecutiveOfficersGrantedOptionsWithNewAppointments_9A3F44E241081DA380D7401C106D0A92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_BB2B02A68107E47FA2BC401C106D6063" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_BB2B02A68107E47FA2BC401C106D6063" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_934BAD48F6B0F9843F45401C106D1558" xlink:type="locator" />
    <link:presentationArc order="9" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_934BAD48F6B0F9843F45401C106D1558" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_E7C1C7EC1CC4A6B0F25B401C106D95E4" xlink:type="locator" />
    <link:presentationArc order="10" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageRemainingContractualTerm2_E7C1C7EC1CC4A6B0F25B401C106D95E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_0FD3E79F326531922294401C106DE0E6" xlink:type="locator" />
    <link:presentationArc order="11" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_0FD3E79F326531922294401C106DE0E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_1957DCED82C28F677188401C106D65DF" xlink:type="locator" />
    <link:presentationArc order="12" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1_1957DCED82C28F677188401C106D65DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_963FD3089E50D468CB07401C106D686B" xlink:type="locator" />
    <link:presentationArc order="13" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice_963FD3089E50D468CB07401C106D686B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_3DC15739AB41E1493D9C401C106D70FD" xlink:type="locator" />
    <link:presentationArc order="14" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue_3DC15739AB41E1493D9C401C106D70FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_25AFE6D23FA5234643BF401C106DD39B" xlink:type="locator" />
    <link:presentationArc order="15" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_25AFE6D23FA5234643BF401C106DD39B" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueStockOptionsMeasurementInput" xlink:label="loc_abus_FairValueStockOptionsMeasurementInput_6FE4B4598B0E7C512E42401C106D60CF" xlink:type="locator" />
    <link:presentationArc order="16" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_abus_FairValueStockOptionsMeasurementInput_6FE4B4598B0E7C512E42401C106D60CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_F53ED98485A868507ACF401C106D6067" xlink:type="locator" />
    <link:presentationArc order="17" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_F53ED98485A868507ACF401C106D6067" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ConversionOfStockSharesConverted1" xlink:label="loc_us-gaap_ConversionOfStockSharesConverted1_2B603235135EA87673EF401C106D3853" xlink:type="locator" />
    <link:presentationArc order="18" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ConversionOfStockSharesConverted1_2B603235135EA87673EF401C106D3853" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_InvestmentOptionsExercisePrice" xlink:label="loc_invest_InvestmentOptionsExercisePrice_F72A9D0EBCFAB4897EE7401C106D2B70" xlink:type="locator" />
    <link:presentationArc order="19" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_invest_InvestmentOptionsExercisePrice_F72A9D0EBCFAB4897EE7401C106D2B70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_02E4A59C1ED6ACAD1E13401C106DFC00" xlink:type="locator" />
    <link:presentationArc order="20" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_02E4A59C1ED6ACAD1E13401C106DFC00" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned" xlink:label="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_48D121FD3D41EFA5FE01401C106D6F8F" xlink:type="locator" />
    <link:presentationArc order="21" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssigned_48D121FD3D41EFA5FE01401C106D6F8F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_FairValueStockOptionsTerm" xlink:label="loc_abus_FairValueStockOptionsTerm_953554EE6A977175B98F401C106D4908" xlink:type="locator" />
    <link:presentationArc order="22" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_abus_FairValueStockOptionsTerm_953554EE6A977175B98F401C106D4908" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPreCombinationServiceAndIncludedAsPartOfTotalPurchasePrice" xlink:label="loc_abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPreCombinationServiceAndIncludedAsPartOfTotalPurchasePrice_513D6E2A88248C77E0BC401C106D04E6" xlink:type="locator" />
    <link:presentationArc order="23" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPreCombinationServiceAndIncludedAsPartOfTotalPurchasePrice_513D6E2A88248C77E0BC401C106D04E6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPostCombinationServiceAndNotIncludedAsPartOfTotalPurchasePrice" xlink:label="loc_abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPostCombinationServiceAndNotIncludedAsPartOfTotalPurchasePrice_82557F33544689306E88401C106D2116" xlink:type="locator" />
    <link:presentationArc order="24" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_abus_BusinessAcquisitionEquityInterestIssuedOrIssuableValueAssignedAttributedAsPostCombinationServiceAndNotIncludedAsPartOfTotalPurchasePrice_82557F33544689306E88401C106D2116" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_71C6058A1DD7DF257055401C106D20A5" xlink:type="locator" />
    <link:presentationArc order="25" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_71C6058A1DD7DF257055401C106D20A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_E9A1C99274EDA46ED60A401C106D4934" xlink:type="locator" />
    <link:presentationArc order="26" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_E9A1C99274EDA46ED60A401C106D4934" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_AF3E916DC1AFB56C28FF401C106DB154" xlink:type="locator" />
    <link:presentationArc order="27" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_AF3E916DC1AFB56C28FF401C106DB154" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_09BFE3BFFAD9A911EE74401C106D1C10" xlink:type="locator" />
    <link:presentationArc order="28" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1904F3AB75DCEEF122F6401C106D966B" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_09BFE3BFFAD9A911EE74401C106D1C10" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationNonVestedStockOptionActivityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_7ECA539788FF8F51C2D53F0C9CDF4077" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_7ECA539788FF8F51C2D53F0C9CDF4077" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_1C4D7118A4CBCB3A28433F0C9CE04D16" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_1C4D7118A4CBCB3A28433F0C9CE04D16" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_1587DCD0C818B154399D3F0C9CE05189" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_1587DCD0C818B154399D3F0C9CE05189" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_249C48431075D9A031F93F0C9CE05A41" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_249C48431075D9A031F93F0C9CE05A41" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_C8D459E2C95C76795AFE3F0C9CE071DB" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_C8D459E2C95C76795AFE3F0C9CE071DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_90DA3034626E049DA7223F0C9CE0AD13" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_27BDDE9F0C03B742764E3F0C9CE03EB6" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_90DA3034626E049DA7223F0C9CE0AD13" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_7ECA539788FF8F51C2D53F0C9CDF4077" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_1E78191A3309E2A393E53F0C9CE1BD2A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_1E78191A3309E2A393E53F0C9CE1BD2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_7987B2041947A21E08583F0C9CE123F5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_7987B2041947A21E08583F0C9CE123F5" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue_5574EABEEFEE4EBF29863F0C9CE1EBBC" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue_5574EABEEFEE4EBF29863F0C9CE1EBBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_3AFC242EB7CE820D305A3F0C9CE1A711" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_3AFC242EB7CE820D305A3F0C9CE1A711" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_9ADEDD0D9C550044D1B83F0C9CE27A83" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_8D8BEC2A1094DBB982053F0C9CE183AB" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_9ADEDD0D9C550044D1B83F0C9CE27A83" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationNonVestedStockOptionActivityOncoreOptionPlanDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_FFDEE16A03AF444B91B1401C240A3882" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_303B75EB77E11B3DA903401C240A2F21" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_FFDEE16A03AF444B91B1401C240A3882" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_303B75EB77E11B3DA903401C240A2F21" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_DECAF7073A4505F3F145401C240A856F" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_303B75EB77E11B3DA903401C240A2F21" xlink:to="loc_us-gaap_AwardTypeAxis_DECAF7073A4505F3F145401C240A856F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CE6D31B930947262CDBB401C240A9362" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_DECAF7073A4505F3F145401C240A856F" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CE6D31B930947262CDBB401C240A9362" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquivalentNumberOfCompanyCommonSharesMember" xlink:label="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_12642DF5C3A0ED4394B8401C240AAA07" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CE6D31B930947262CDBB401C240A9362" xlink:to="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_12642DF5C3A0ED4394B8401C240AAA07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_441B5E894553FB7D905D401C240AD2B0" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_303B75EB77E11B3DA903401C240A2F21" xlink:to="loc_us-gaap_PlanNameAxis_441B5E894553FB7D905D401C240AD2B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_4B6FB22F6B869F7F7491401C240A4428" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_441B5E894553FB7D905D401C240AD2B0" xlink:to="loc_us-gaap_PlanNameDomain_4B6FB22F6B869F7F7491401C240A4428" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OnCoreOptionPlanMember" xlink:label="loc_abus_OnCoreOptionPlanMember_4BB16CF2DA82CDBDFD9C401C240A00A3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_4B6FB22F6B869F7F7491401C240A4428" xlink:to="loc_abus_OnCoreOptionPlanMember_4BB16CF2DA82CDBDFD9C401C240A00A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_E08E33EF0BD9A3271BC7401C240A0925" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_303B75EB77E11B3DA903401C240A2F21" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_E08E33EF0BD9A3271BC7401C240A0925" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_E08E33EF0BD9A3271BC7401C240A0925" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_886C82396CA860AB615A401C240A2CE3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_886C82396CA860AB615A401C240A2CE3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_F2BACD26A6D1A8ECBCE9401C240AB92F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares_F2BACD26A6D1A8ECBCE9401C240AB92F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_E330F30E12DEFE95A44D401C240A3867" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares_E330F30E12DEFE95A44D401C240A3867" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_46F1E9BBDF38ADD9F68D401C240A3B93" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfSharesRollForward_2C40517A988B47CF3C03401C240A82C0" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares_46F1E9BBDF38ADD9F68D401C240A3B93" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_77961E0271F999377098401C240A35A5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_E08E33EF0BD9A3271BC7401C240A0925" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_77961E0271F999377098401C240A35A5" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_CAE659E5F2C9C0E4A35E401C240AF909" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_77961E0271F999377098401C240A35A5" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_CAE659E5F2C9C0E4A35E401C240AF909" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue_14A135B3EE642991E39D401C240A4C80" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_77961E0271F999377098401C240A35A5" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsVestedInPeriodWeightedAverageFairValue_14A135B3EE642991E39D401C240A4C80" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue" xlink:label="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_EAA6E6C2A966D79FEE2E401C240AFD12" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValueAbstract_77961E0271F999377098401C240A35A5" xlink:to="loc_abus_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOptionsNonvestedWeightedAverageFairValue_EAA6E6C2A966D79FEE2E401C240AFD12" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationOutstandingOptionsUnderOncoreOptionPlanDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_62D1BFF577AC3DE2E93D401C2233FF37" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3171B2284FC527E6A60C401C2233DDB5" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_62D1BFF577AC3DE2E93D401C2233FF37" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3171B2284FC527E6A60C401C2233DDB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_EAC93D8D4E58202982CB401C2233F0A3" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3171B2284FC527E6A60C401C2233DDB5" xlink:to="loc_us-gaap_AwardTypeAxis_EAC93D8D4E58202982CB401C2233F0A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_F5C976E26215889A793C401C22341651" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_EAC93D8D4E58202982CB401C2233F0A3" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_F5C976E26215889A793C401C22341651" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquivalentNumberOfCompanyCommonSharesMember" xlink:label="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_BB7B5329C3BB86DF5865401C2234827E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_F5C976E26215889A793C401C22341651" xlink:to="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_BB7B5329C3BB86DF5865401C2234827E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_01E0F789A837A32E96B4401C2234E69F" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3171B2284FC527E6A60C401C2233DDB5" xlink:to="loc_us-gaap_PlanNameAxis_01E0F789A837A32E96B4401C2234E69F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_4ACEE3D7AC126487AD90401C223434EE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_01E0F789A837A32E96B4401C2234E69F" xlink:to="loc_us-gaap_PlanNameDomain_4ACEE3D7AC126487AD90401C223434EE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OnCoreOptionPlanMember" xlink:label="loc_abus_OnCoreOptionPlanMember_0E5C88544F8693DD6CC9401C22350A93" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_4ACEE3D7AC126487AD90401C223434EE" xlink:to="loc_abus_OnCoreOptionPlanMember_0E5C88544F8693DD6CC9401C22350A93" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2F5F2648969B95DE3A99401C223530EB" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3171B2284FC527E6A60C401C2233DDB5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2F5F2648969B95DE3A99401C223530EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2F5F2648969B95DE3A99401C223530EB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_970B7C0ADAD31968989B401C22354BF1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_970B7C0ADAD31968989B401C22354BF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_631120CC7BDA2E8BAC33401C22368A91" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_631120CC7BDA2E8BAC33401C22368A91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_0D4AFC2B2B4BB2D91D2F401C22369C75" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_0D4AFC2B2B4BB2D91D2F401C22369C75" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_5FFB61B368BBCA006DE1401C2236FFDD" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_C2375092F81BFBFF640F401C22351988" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_5FFB61B368BBCA006DE1401C2236FFDD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_DC0BFFA00C9D5E4002D6401C2236391D" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2F5F2648969B95DE3A99401C223530EB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_DC0BFFA00C9D5E4002D6401C2236391D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E90B3635BAB06FAC734B401C2236CCA7" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_DC0BFFA00C9D5E4002D6401C2236391D" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E90B3635BAB06FAC734B401C2236CCA7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_1D0D01A91BC89361FB99401C22370169" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_DC0BFFA00C9D5E4002D6401C2236391D" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_1D0D01A91BC89361FB99401C22370169" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_AD91706B1C913958FB7C401C2237E852" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_DC0BFFA00C9D5E4002D6401C2236391D" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_AD91706B1C913958FB7C401C2237E852" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationOutstandingOptionsUnderProtivaOptionPlanDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_94C40D5B2B06CF115C87401C1FFBFEF4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4296C37BE180F9674663401C1FFB85AC" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_94C40D5B2B06CF115C87401C1FFBFEF4" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4296C37BE180F9674663401C1FFB85AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_FB0A89A1422ADF1FE63B401C1FFB8130" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4296C37BE180F9674663401C1FFB85AC" xlink:to="loc_us-gaap_AwardTypeAxis_FB0A89A1422ADF1FE63B401C1FFB8130" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D079AB290CBBAA347658401C1FFB6345" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_FB0A89A1422ADF1FE63B401C1FFB8130" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D079AB290CBBAA347658401C1FFB6345" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EquivalentNumberOfCompanyCommonSharesMember" xlink:label="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_B58D532334DA59DEA165401C1FFC4859" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_D079AB290CBBAA347658401C1FFB6345" xlink:to="loc_abus_EquivalentNumberOfCompanyCommonSharesMember_B58D532334DA59DEA165401C1FFC4859" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_D420998832AF3662DD06401C1FFC2C86" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4296C37BE180F9674663401C1FFB85AC" xlink:to="loc_us-gaap_PlanNameAxis_D420998832AF3662DD06401C1FFC2C86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_20982009EBBEA8A3B32F401C1FFCB062" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_D420998832AF3662DD06401C1FFC2C86" xlink:to="loc_us-gaap_PlanNameDomain_20982009EBBEA8A3B32F401C1FFCB062" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ProtivaShareOptionsMember" xlink:label="loc_abus_ProtivaShareOptionsMember_DEA3E254A9007E520F8E401C1FFCC737" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_20982009EBBEA8A3B32F401C1FFCB062" xlink:to="loc_abus_ProtivaShareOptionsMember_DEA3E254A9007E520F8E401C1FFCC737" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_DD5EB40F64F1DE90C626401C1FFD07E4" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_4296C37BE180F9674663401C1FFB85AC" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_DD5EB40F64F1DE90C626401C1FFD07E4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_DD5EB40F64F1DE90C626401C1FFD07E4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6C1A77752C65D5473933401C1FFD755E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_6C1A77752C65D5473933401C1FFD755E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_1CE5134A3237E8F1344A401C1FFDB9B5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_1CE5134A3237E8F1344A401C1FFDB9B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_811594F18D5FEBA564E8401C1FFEFB09" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_811594F18D5FEBA564E8401C1FFEFB09" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_4793B469AA4B4E0CE23E401C1FFEE828" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_9C894929C95D6C9EBEA7401C1FFD2F32" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_4793B469AA4B4E0CE23E401C1FFEE828" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_DD5EB40F64F1DE90C626401C1FFD07E4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_F15F7E3E50F75FE14AD1401C1FFEB088" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_F15F7E3E50F75FE14AD1401C1FFEB088" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_20A0F152ACFD157C140E401C1FFE958E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_20A0F152ACFD157C140E401C1FFE958E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_4B3424BF90193BDE6E1E401C1FFF6A6A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_4B3424BF90193BDE6E1E401C1FFF6A6A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_76E73A3A2DC2931126B7401C1FFF8389" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_2B3E4E3B7A0232E3D80F401C1FFEF767" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_76E73A3A2DC2931126B7401C1FFF8389" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationStockBasedCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_B3C8CB2643802ADBBB9A3F0C9C6BAC0B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_18D87AE4C29923C198233F0C9C6B9C8E" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_B3C8CB2643802ADBBB9A3F0C9C6BAC0B" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_18D87AE4C29923C198233F0C9C6B9C8E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_71FD95C08C94B5144CD63F0C9C6BDC0C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_18D87AE4C29923C198233F0C9C6B9C8E" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_71FD95C08C94B5144CD63F0C9C6BDC0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_4AD9A99DA09B9A2176613F0C9C6C26F4" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_71FD95C08C94B5144CD63F0C9C6BDC0C" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_4AD9A99DA09B9A2176613F0C9C6C26F4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_7A25C6B155CAAF61CC2D3F0C9C6C3CF8" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_4AD9A99DA09B9A2176613F0C9C6C26F4" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_7A25C6B155CAAF61CC2D3F0C9C6C3CF8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_GeneralAndAdministrativeExpenseMember" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_BE2A5CA9EC4D0E2BC0173F0C9C6CC07C" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_4AD9A99DA09B9A2176613F0C9C6C26F4" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_BE2A5CA9EC4D0E2BC0173F0C9C6CC07C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_44669B8F63A3900B09603F0C9C6DC205" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_18D87AE4C29923C198233F0C9C6B9C8E" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_44669B8F63A3900B09603F0C9C6DC205" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_0D9DD41CBD632C75ED8D3F0C9C6DE792" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_44669B8F63A3900B09603F0C9C6DC205" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_0D9DD41CBD632C75ED8D3F0C9C6DE792" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionActivityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_D380F3A7E382FF2C0934594001DBFC95" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8175ACA7E032D7FBE2A7594001E2B458" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_D380F3A7E382FF2C0934594001DBFC95" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8175ACA7E032D7FBE2A7594001E2B458" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_39630A46881F81674399594001E59EB9" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8175ACA7E032D7FBE2A7594001E2B458" xlink:to="loc_us-gaap_PlanNameAxis_39630A46881F81674399594001E59EB9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_D8CFA4AE175439A10C2C594001E64DFE" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_39630A46881F81674399594001E59EB9" xlink:to="loc_us-gaap_PlanNameDomain_D8CFA4AE175439A10C2C594001E64DFE" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ArbutusPlansMember" xlink:label="loc_abus_ArbutusPlansMember_1459D887AE89ADE451E7594001E6902B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_D8CFA4AE175439A10C2C594001E64DFE" xlink:to="loc_abus_ArbutusPlansMember_1459D887AE89ADE451E7594001E6902B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_234F60006705B9783ACB594001E733FE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_8175ACA7E032D7FBE2A7594001E2B458" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_234F60006705B9783ACB594001E733FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_234F60006705B9783ACB594001E733FE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_AA8AFA43C294D6ED59C2594001EE0B39" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_AA8AFA43C294D6ED59C2594001EE0B39" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_A47029F386EF57369694594001EF919E" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_A47029F386EF57369694594001EF919E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_35006C491D4FF4C74CEF594001EFBB34" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_35006C491D4FF4C74CEF594001EFBB34" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_44D676C9C65A1856A907594001EF891D" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_44D676C9C65A1856A907594001EF891D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_79CBC96D10125FD439A0594001F02F5C" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_D4ADAAC1C32954E8DD99594001E70E1B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_79CBC96D10125FD439A0594001F02F5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_234F60006705B9783ACB594001E733FE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_B833E4FE527F7CC3C2A8594001F05A49" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_B833E4FE527F7CC3C2A8594001F05A49" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_F60CEC88977AEC29F765594001F0F4B1" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_F60CEC88977AEC29F765594001F0F4B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_379DD8FFB24E0EFF08ED594001F03969" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_379DD8FFB24E0EFF08ED594001F03969" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_E4497CADFE0C16C51D92594001F16647" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_E4497CADFE0C16C51D92594001F16647" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_28B3D93562601D51106B594001F159CF" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_E6D852126887C46BB770594001F0B54A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_28B3D93562601D51106B594001F159CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_24B941AA8275DEA69E7E594001F11A0A" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_234F60006705B9783ACB594001E733FE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_24B941AA8275DEA69E7E594001F11A0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_B0482BF51E11C117A6E8594001F186DB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_24B941AA8275DEA69E7E594001F11A0A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_B0482BF51E11C117A6E8594001F186DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_94EEA20E71EB137FBCEB594001F16769" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_24B941AA8275DEA69E7E594001F11A0A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_94EEA20E71EB137FBCEB594001F16769" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_730E42EA9D5B485812A1594001F20AA3" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_24B941AA8275DEA69E7E594001F11A0A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_730E42EA9D5B485812A1594001F20AA3" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionActivityForLiabilityClassifiedOptionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_5D6A1F573C5A52DE508D401C1BB64DAA" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92ECCF6AA4E86B7F1ED7401C1BB6EC2C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_5D6A1F573C5A52DE508D401C1BB64DAA" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92ECCF6AA4E86B7F1ED7401C1BB6EC2C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_10FADEEA4C0A7BC9B75F401C1BB6AAAB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92ECCF6AA4E86B7F1ED7401C1BB6EC2C" xlink:to="loc_us-gaap_AwardTypeAxis_10FADEEA4C0A7BC9B75F401C1BB6AAAB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_56D7D90086BC9E0FB6E8401C1BB7EE14" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_10FADEEA4C0A7BC9B75F401C1BB6AAAB" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_56D7D90086BC9E0FB6E8401C1BB7EE14" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_CA33E8EC7F1EC7060971401C1BB73150" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_56D7D90086BC9E0FB6E8401C1BB7EE14" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_CA33E8EC7F1EC7060971401C1BB73150" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2C0EBC3EE3950CE70AE8401C1BB73428" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92ECCF6AA4E86B7F1ED7401C1BB6EC2C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2C0EBC3EE3950CE70AE8401C1BB73428" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2C0EBC3EE3950CE70AE8401C1BB73428" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_CBD5231FAFFBCF338025401C1BB82198" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_CBD5231FAFFBCF338025401C1BB82198" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_61932C103E3BD0DC91CC401C1BB84ABB" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_61932C103E3BD0DC91CC401C1BB84ABB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_B492C5A61EFB7ED493D9401C1BB8BF67" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod_B492C5A61EFB7ED493D9401C1BB8BF67" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_8AA31E562F9C52ACCA9A401C1BB84838" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_699DB30CDE82E92A85C8401C1BB89A69" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_8AA31E562F9C52ACCA9A401C1BB84838" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2C0EBC3EE3950CE70AE8401C1BB73428" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_06B2F75BFEEFBFBD1E21401C1BB9F0D6" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_06B2F75BFEEFBFBD1E21401C1BB9F0D6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_FC5945ACEF3220200CAE401C1BB95624" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice_FC5945ACEF3220200CAE401C1BB95624" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_758E9B78A4E1A37ACB79401C1BBA433C" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice_758E9B78A4E1A37ACB79401C1BBA433C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E9590235CABAE777B893401C1BBAC467" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_C90B151D1808253E308C401C1BB918D4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_E9590235CABAE777B893401C1BBAC467" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_19CA5F4F7451900954AA401C1BBAAB0B" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_2C0EBC3EE3950CE70AE8401C1BB73428" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_19CA5F4F7451900954AA401C1BBAAB0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_12CD4E28E182CFCAA3D3401C1BBA1F19" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_19CA5F4F7451900954AA401C1BBAAB0B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_12CD4E28E182CFCAA3D3401C1BBA1F19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_497074ABEAA39B6CF719401C1BBB23C4" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_19CA5F4F7451900954AA401C1BBAAB0B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_497074ABEAA39B6CF719401C1BBB23C4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_4FA2306EC4B20B80C2EC401C1BBBEFA6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_19CA5F4F7451900954AA401C1BBAAB0B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_4FA2306EC4B20B80C2EC401C1BBBEFA6" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationStockOptionsOutstandingDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_FB6FBC50A0DA336408623F0C9CE7EB7A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTable_77B8991258DA8B8EC52D3F0C9CE87AEB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_FB6FBC50A0DA336408623F0C9CE7EB7A" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTable_77B8991258DA8B8EC52D3F0C9CE87AEB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_3B86D3D92C3F2A1C888A3F0C9CE81A31" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTable_77B8991258DA8B8EC52D3F0C9CE87AEB" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_3B86D3D92C3F2A1C888A3F0C9CE81A31" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeAxis_3B86D3D92C3F2A1C888A3F0C9CE81A31" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range1Member" xlink:label="loc_abus_Range1Member_9AEB49DA27D463740AED3F0C9CE9E2DA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range1Member_9AEB49DA27D463740AED3F0C9CE9E2DA" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range2Member" xlink:label="loc_abus_Range2Member_A3FCDB009820A471E54C3F0C9CE9399B" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range2Member_A3FCDB009820A471E54C3F0C9CE9399B" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range3Member" xlink:label="loc_abus_Range3Member_43C91FFD958E16FC85023F0C9CE9EF7E" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range3Member_43C91FFD958E16FC85023F0C9CE9EF7E" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range4Member" xlink:label="loc_abus_Range4Member_6CF394666C8D01EA6C193F0C9CE9039F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range4Member_6CF394666C8D01EA6C193F0C9CE9039F" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range5Member" xlink:label="loc_abus_Range5Member_DE144C43475BFF1A89DA3F0C9CE98153" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range5Member_DE144C43475BFF1A89DA3F0C9CE98153" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range6Member" xlink:label="loc_abus_Range6Member_59A0DF5282E71545D9583F0C9CE98CE0" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range6Member_59A0DF5282E71545D9583F0C9CE98CE0" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_Range7Member" xlink:label="loc_abus_Range7Member_26A7CD19E933937179BA3F0C9CEABDA6" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_Range7Member_26A7CD19E933937179BA3F0C9CEABDA6" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TotalRangeMember" xlink:label="loc_abus_TotalRangeMember_1AED3F11DBBB8AD181353F0C9CEADBC6" xlink:type="locator" />
    <link:presentationArc order="8" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeDomain_C1FBBEE4E8B63EFE8CE53F0C9CE806B1" xlink:to="loc_abus_TotalRangeMember_1AED3F11DBBB8AD181353F0C9CEADBC6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTable_77B8991258DA8B8EC52D3F0C9CE87AEB" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_E5E78CFA7F34A5455B463F0C9CEAB5D0" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLowerRangeLimit_E5E78CFA7F34A5455B463F0C9CEAB5D0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_6EC97EC370A1946158D33F0C9CEA7379" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeUpperRangeLimit_6EC97EC370A1946158D33F0C9CEA7379" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions_7FBEEB6FEED82799D6703F0C9CEB52B9" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfOutstandingOptions_7FBEEB6FEED82799D6703F0C9CEB52B9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_34B5F59897158E93FE183F0C9CEBD4A6" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_34B5F59897158E93FE183F0C9CEBD4A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_F4F05DDF0BFD687E725C3F0C9CEBFE35" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_F4F05DDF0BFD687E725C3F0C9CEBFE35" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions" xlink:label="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions_44B0A3A94EEA6E53330F3F0C9CEB21BD" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeNumberOfExercisableOptions_44B0A3A94EEA6E53330F3F0C9CEB21BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1" xlink:label="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1_DE828E909C99D5E54D953F0C9CEB4623" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeLineItems_23F5CF399B9FC80BD4533F0C9CEA95AE" xlink:to="loc_us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1_DE828E909C99D5E54D953F0C9CEB4623" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationTables" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract" xlink:label="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_668AF554C1767A822FB63F2C41F45A15" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_54E267BBCD9A5781C3E83F0C9D3F4CFA" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract_668AF554C1767A822FB63F2C41F45A15" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_54E267BBCD9A5781C3E83F0C9D3F4CFA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_A01733974C4A30560E003F0C9D405455" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_54E267BBCD9A5781C3E83F0C9D3F4CFA" xlink:to="loc_us-gaap_AwardTypeAxis_A01733974C4A30560E003F0C9D405455" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_980798E0E8E5321630333F0C9D407705" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_A01733974C4A30560E003F0C9D405455" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_980798E0E8E5321630333F0C9D407705" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_34A8FBAAE3066CDDAEF63F0C9D40FE64" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_980798E0E8E5321630333F0C9D407705" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_34A8FBAAE3066CDDAEF63F0C9D40FE64" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_9541D9E1FEC344705ECF3F0C9D41A3F8" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_54E267BBCD9A5781C3E83F0C9D3F4CFA" xlink:to="loc_us-gaap_PlanNameAxis_9541D9E1FEC344705ECF3F0C9D41A3F8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_910E9101E3ED04C623293F0C9D41ED66" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_9541D9E1FEC344705ECF3F0C9D41A3F8" xlink:to="loc_us-gaap_PlanNameDomain_910E9101E3ED04C623293F0C9D41ED66" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ProtivaOptionPlanMember" xlink:label="loc_abus_ProtivaOptionPlanMember_1908C2BA32DD317437483F0C9D41DF8D" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_910E9101E3ED04C623293F0C9D41ED66" xlink:to="loc_abus_ProtivaOptionPlanMember_1908C2BA32DD317437483F0C9D41DF8D" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_OnCoreOptionPlanMember" xlink:label="loc_abus_OnCoreOptionPlanMember_FBAAF1A872FFF5C66D853F0C9D42CEA5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_910E9101E3ED04C623293F0C9D41ED66" xlink:to="loc_abus_OnCoreOptionPlanMember_FBAAF1A872FFF5C66D853F0C9D42CEA5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_54E267BBCD9A5781C3E83F0C9D3F4CFA" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_B97BE54FA31D4BA120163F0C9D422E01" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_B97BE54FA31D4BA120163F0C9D422E01" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_TemporalDiagramOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTableTextBlock" xlink:label="loc_abus_TemporalDiagramOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTableTextBlock_AD3EBC7B931DDA2B05963F0C9D43AAAE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_abus_TemporalDiagramOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTableTextBlock_AD3EBC7B931DDA2B05963F0C9D43AAAE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock_3DF93836C1BD870C7EA23F0C9D431760" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ScheduleOfNonvestedShareActivityTableTextBlock_3DF93836C1BD870C7EA23F0C9D431760" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValueTableTextBlock" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValueTableTextBlock_654C4D636989636EA2783F0C9D43714F" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValueTableTextBlock_654C4D636989636EA2783F0C9D43714F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_7F7E5A49050739A32AB43F0C9D42F485" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_7F7E5A49050739A32AB43F0C9D42F485" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAndExercisableTableTextBlock" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAndExercisableTableTextBlock_CBFA486921BC9AA64E433F0C9D432596" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAndExercisableTableTextBlock_CBFA486921BC9AA64E433F0C9D432596" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_3A7F8E8419603486655D3F0C9D436531" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_195C00E30BE806E28BE03F0C9D420BB6" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_3A7F8E8419603486655D3F0C9D436531" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationValuationAssumptionsForLiabilityClassifiedOptionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_69C33A8DEE2906D5D1523F0C9CD2FB6D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CEB032FF03753BEA939C3F0C9CD2D24C" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_69C33A8DEE2906D5D1523F0C9CD2FB6D" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CEB032FF03753BEA939C3F0C9CD2D24C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_D093BCAA2D4ADD229A1B3F0C9CD3995B" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CEB032FF03753BEA939C3F0C9CD2D24C" xlink:to="loc_us-gaap_AwardTypeAxis_D093BCAA2D4ADD229A1B3F0C9CD3995B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EA785247B318F010ECC3F0C9CD31F5A" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_D093BCAA2D4ADD229A1B3F0C9CD3995B" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EA785247B318F010ECC3F0C9CD31F5A" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionLiabilityClassifiedMember" xlink:label="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_4E5E342F6D15E970503D3F0C9CD39230" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EA785247B318F010ECC3F0C9CD31F5A" xlink:to="loc_abus_EmployeeStockOptionLiabilityClassifiedMember_4E5E342F6D15E970503D3F0C9CD39230" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_CEB032FF03753BEA939C3F0C9CD2D24C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharePrice" xlink:label="loc_us-gaap_SharePrice_058D3EBFD3ED4F8B31973F4AA9781CBB" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_us-gaap_SharePrice_058D3EBFD3ED4F8B31973F4AA9781CBB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_6631B9571E691A1D90953F0C9CD4D837" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_6631B9571E691A1D90953F0C9CD4D837" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_26CFD1822FE4A18262CD3F0C9CD433F2" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_26CFD1822FE4A18262CD3F0C9CD433F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_ECC724CDC18DCF82D89B3F0C9CD4ED0C" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_ECC724CDC18DCF82D89B3F0C9CD4ED0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_FAE54501B1B024B9A9B03F0C9CD4FDB2" xlink:type="locator" />
    <link:presentationArc order="5" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_FAE54501B1B024B9A9B03F0C9CD4FDB2" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsOutstandingFairValuePrice" xlink:label="loc_abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsOutstandingFairValuePrice_FD6A4401EB2DCABB0A903F0C9CD5D3BA" xlink:type="locator" />
    <link:presentationArc order="6" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_abus_SharebasedCompensationArrangementbySharebasedPaymentAwardOptionsOutstandingFairValuePrice_FD6A4401EB2DCABB0A903F0C9CD5D3BA" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure" xlink:label="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_A8FD144BFA7A6A4752853F0C9CD5AC80" xlink:type="locator" />
    <link:presentationArc order="7" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_B1D7181CA67FC9A5188B3F0C9CD4B4D9" xlink:to="loc_abus_EmployeeStockOptionsLiabilityClassifiedOutstandingFairValueDisclosure_A8FD144BFA7A6A4752853F0C9CD5AC80" xlink:type="arc" />
  </link:presentationLink>
  <link:presentationLink xlink:role="http://www.tekmirapharm.com/role/StockBasedCompensationValuationAssumptionsForStockOptionsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_StockholdersEquityNoteAbstract" xlink:label="loc_us-gaap_StockholdersEquityNoteAbstract_7E58C01686E5D0FE7BD93F0C9CD90FE8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92669C5681E97FF375393F0C9CD90072" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityNoteAbstract_7E58C01686E5D0FE7BD93F0C9CD90FE8" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92669C5681E97FF375393F0C9CD90072" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameAxis" xlink:label="loc_us-gaap_PlanNameAxis_CF0F554D7F78494B92EE3F0C9CD93D92" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92669C5681E97FF375393F0C9CD90072" xlink:to="loc_us-gaap_PlanNameAxis_CF0F554D7F78494B92EE3F0C9CD93D92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_PlanNameDomain" xlink:label="loc_us-gaap_PlanNameDomain_28FE6C897B6E6126DE4A3F0C9CD93280" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_CF0F554D7F78494B92EE3F0C9CD93D92" xlink:to="loc_us-gaap_PlanNameDomain_28FE6C897B6E6126DE4A3F0C9CD93280" xlink:type="arc" />
    <link:loc xlink:href="abus-20181231.xsd#abus_ArbutusPlansMember" xlink:label="loc_abus_ArbutusPlansMember_37537222D3AFBC48A68B3F0C9CDAE3DD" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_28FE6C897B6E6126DE4A3F0C9CD93280" xlink:to="loc_abus_ArbutusPlansMember_37537222D3AFBC48A68B3F0C9CDAE3DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_92669C5681E97FF375393F0C9CD90072" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_31CC108D024DD34074F33F0C9CDADF88" xlink:type="locator" />
    <link:presentationArc order="1" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_31CC108D024DD34074F33F0C9CDADF88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_82886B450B1FD32F5D043F0C9CDBD1EE" xlink:type="locator" />
    <link:presentationArc order="2" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_82886B450B1FD32F5D043F0C9CDBD1EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_FBE0C66193D960D34E783F0C9CDB776D" xlink:type="locator" />
    <link:presentationArc order="3" preferredLabel="http://www.xbrl.org/2003/role/terseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_FBE0C66193D960D34E783F0C9CDB776D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2018/elts/us-gaap-2018-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_B993A6253CDD21191E443F0C9CDB248E" xlink:type="locator" />
    <link:presentationArc order="4" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_82173AC5FEB1117016273F0C9CDAB9B5" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_B993A6253CDD21191E443F0C9CDB248E" xlink:type="arc" />
  </link:presentationLink>
</link:linkbase>